TY - BOOK ID - 33634 TI - Fatty Acids and Cardiometabolic Health AU - Wu, Jason AU - Marklund, Matti PY - 2019 SN - 9783038978909 / 9783038978916 DB - DOAB KW - omega-3 KW - cardiovascular disease KW - statins KW - type 2 diabetes mellitus KW - medium-chain triglyceride KW - long-chain triglyceride KW - lipid metabolism KW - klotho KW - CKD KW - fish oil KW - fibrosis KW - inflammation KW - cardiometabolic disease KW - unsaturated fat KW - Mediterranean diet KW - low-fat diet KW - alternatively activated macrophages KW - perivascular adipose tissue KW - type 2 cytokines KW - erucic acid KW - fish KW - seafood KW - furan fatty acids KW - docosapentaenoic acid KW - conjugated fatty acids KW - cardiovascular disease KW - metabolic disease KW - blood lipids KW - inflammation KW - antioxidant KW - CYP450 eicosanoids KW - omega-3 PUFA KW - omega-6 PUFA KW - blood pressure KW - hemodynamics KW - children KW - EETs KW - EEQs KW - fatty acid KW - diet KW - genotype KW - human KW - FADS KW - fatty acid KW - desaturase KW - Genome-wide association study (GWAS) KW - Insulin sensitivity KW - adipose tissue KW - cholesterol ester KW - omega 3 KW - PUFA KW - n-3 PUFA KW - COPD KW - inflammation KW - coronary artery disease KW - ischemic heart disease KW - CAD KW - CHD KW - fat KW - obesity KW - body weight KW - cohort study KW - substitution models KW - epidemiology KW - prospective cohort study KW - n-6 fatty acids KW - n-3 fatty acids KW - linoleic acid KW - arachidonic acid UR - https://www.doabooks.org/doab?func=search&query=rid:33634 AB - The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other mechanisms including effects on glucose metabolism, body fat distribution, blood pressure, inflammation, and heart rate. Furthermore, studies evaluating single fatty acids have challenged the simplistic view of shared health effects within fatty acid groups categorized by degree of saturation. In addition, investigations of endogenous fatty acid metabolism, including genetic studies of fatty acid metabolizing enzymes, and the identification of novel metabolically derived fatty acids have further increased the complexity of fatty acids’ health impacts. This Special Issue aims to include original research and up-to-date reviews on genetic and dietary modulation of fatty acids, and the role and function of dietary and metabolically derived fatty acids in cardiometabolic health. ER -