TY - BOOK ID - 35935 TI - Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation AU - Casamassimi, Amelia AU - Ciccodicola, Alfredo PY - 2019 SN - 9783039212651 / 9783039212668 DB - DOAB KW - major depressive disorder KW - glioblastoma KW - differentially expressed genes KW - transcriptomics KW - common pathway KW - mouse KW - miR-25-3p KW - Akt1 KW - AP-2? KW - promoter KW - cell metabolism KW - p57Kip2 KW - CDKN1C KW - epigenetics KW - disease KW - cell differentiation KW - placenta KW - long non-coding RNA (lncRNA) KW - human KW - pregnancy KW - high-throughput RNA sequencing (RNA-Seq) KW - transcriptome KW - Rsh regulon KW - Novosphingobium pentaromativorans US6-1 KW - sphingomonads KW - RNA-seq KW - N-acyl-l-homoserine lactone KW - ppGpp KW - selenium KW - selenocysteine KW - selenoproteins KW - selenocysteine insertion sequence KW - nonsense-mediated decay KW - G-quadruplex KW - transcriptional regulation KW - promoter KW - CRISPR/Cas9 KW - PRDM gene family KW - TCGA data analysis KW - somatic mutations KW - transcriptome profiling KW - human malignancies KW - tristetraprolin (TTP) KW - tumorigenesis KW - posttranscriptional regulation KW - adenosine and uridine-rich elements (AREs) KW - circRNA-disease associations KW - pathway KW - heterogeneous network KW - Patau Syndrome KW - cytogenetics KW - FOXO1 KW - transcription factor KW - molecular pathways KW - bioinformatics KW - molecular docking KW - and drug design KW - transcription regulation KW - gene expression KW - causal inference KW - enhancer activity KW - insect KW - transcription factors KW - structures and functions KW - research methods KW - progress and prospects KW - Pax3 KW - Pteria penguin (Röding, 1798) KW - tyrosinase KW - melanin KW - RNA interference KW - liquid chromatograph-tandem mass spectrometer (LC-MS/MS) KW - epigenetics KW - gene expression KW - nutrition KW - transcription KW - disorders KW - mechanisms KW - Crassostrea gigas KW - Pacific oyster KW - pediveliger larvae KW - bioadhesive KW - transcriptome KW - gene expression KW - interactome KW - microscopy KW - fertilization KW - self-incompatibility KW - transcriptome KW - tea KW - long non-coding RNAs KW - cancer KW - acute leukemia KW - therapeutic targets KW - Adiponectin KW - cancer KW - Adiponectin receptors KW - obesity KW - inflammatory response KW - inflammation KW - nutritional status KW - n/a UR - https://www.doabooks.org/doab?func=search&query=rid:35935 AB - Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses. ER -