Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications
Abstract
A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different fabrication methods were analyzed to determine mass fabrication capabilities. These fabrication methods also allowed the production of fully structured microchannels to tune the fluids behavior within.
Keywords
KunststoffverarbeitungLab-on-a-Chip; Mikrofluidik; Microfabrication; Lab-on-a-Chip; Polymer processing; Mikrofertigung; MicrofluidicsISBN
9783731502975Publisher
KIT Scientific PublishingPublisher website
http://www.ksp.kit.edu/Publication date and place
2014Series
Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik,Classification
Technology: general issues