Search results: Found 9

Listing 1 - 9 of 9
Sort by
Information Theory in Neuroscience

Authors: ---
ISBN: 9783038976646 Year: Pages: 280 DOI: 10.3390/books978-3-03897-665-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Mathematics --- Science (General)
Added to DOAB on : 2019-03-21 15:50:41
License:

Loading...
Export citation

Choose an application

Abstract

As the ultimate information processing device, the brain naturally lends itself to being studied with information theory. The application of information theory to neuroscience has spurred the development of principled theories of brain function, and has led to advances in the study of consciousness, as well as to the development of analytical techniques to crack the neural code—that is, to unveil the language used by neurons to encode and process information. In particular, advances in experimental techniques enabling the precise recording and manipulation of neural activity on a large scale now enable for the first time the precise formulation and the quantitative testing of hypotheses about how the brain encodes and transmits the information used for specific functions across areas. This Special Issue presents twelve original contributions on novel approaches in neuroscience using information theory, and on the development of new information theoretic results inspired by problems in neuroscience.

Towards New Promising Discoveries for Lung Cancer Patients: A Selection of Papers from the First Joint Meeting on Lung Cancer of the FHU OncoAge (Nice, France) and the MD Anderson Cancer Center (Houston, TX, USA)

Authors: --- ---
ISBN: 9783039214518 / 9783039214525 Year: Pages: 230 DOI: 10.3390/books978-3-03921-452-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Oncology
Added to DOAB on : 2019-12-09 11:49:15
License:

Loading...
Export citation

Choose an application

Abstract

This Special Issue of Cancers (Basel) is mainly dedicated to selecting papers from the talks given during the first Joint Meeting on Lung Cancer (JMLC) between the MD Anderson Cancer Center (Houston, Texas USA) and the Hospital University Federation (HUF) OncoAge (University Côte d’Azur, Nice, France) (Nice, September 2018). The central theme of JMLC is to discuss new advances and exchange ideas regarding lung cancer. Notably, the talks covered different topics on new therapeutic strategies (targeted therapy and immuno-oncology), molecular and cellular biology, biomarkers, and the epidemiology of lung cancer. Special attention was also given to lung cancer in elderly patients. The articles published in this Special Issue covered subjects such as the assessment of new biomarkers and new approaches for the early detection of lung cancer, epidemiological data, and emphasized a place for the newly characterized cellular pathways in lung cancer, which opens room for therapeutic perspectives for lung cancer patients.

MicroRNA as Biomarkers in Cancer Diagnostics and Therapy

Author:
ISBN: 9783039212491 / 9783039212507 Year: Pages: 166 DOI: 10.3390/books978-3-03921-250-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Microbiology
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to represent unique microRNA genes in humans, with an increasing number of mechanistic roles identified in developmental, physiological, and pathological processes. Thus, dysregulation of a few key microRNAs can have a profound global effect on the gene expression and molecular programs of a cell. This great potential for clinical intervention has captured the interest and imagination of researchers in many fields. However, very few fields have been as prolific as the field of cancer research. This Special Issue provides but a glimpse of the large body of literature of microRNA biology in cancer research, containing 4 original research studies and 4 review articles that focus on specific hematologic or solid tumors in disease. Collectively, these articles highlight state-of-the-art approaches and methodologies for microRNA detection in tissue, blood, and other body fluids in a range of biomarkers applications, from early cancer detection to prognosis and treatment response. The articles also address some of the challenges regarding clinical implementation.

Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation

Authors: ---
ISBN: 9783039212651 / 9783039212668 Year: Pages: 356 DOI: 10.3390/books978-3-03921-266-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses.

Keywords

major depressive disorder --- glioblastoma --- differentially expressed genes --- transcriptomics --- common pathway --- mouse --- miR-25-3p --- Akt1 --- AP-2? --- promoter --- cell metabolism --- p57Kip2 --- CDKN1C --- epigenetics --- disease --- cell differentiation --- placenta --- long non-coding RNA (lncRNA) --- human --- pregnancy --- high-throughput RNA sequencing (RNA-Seq) --- transcriptome --- Rsh regulon --- Novosphingobium pentaromativorans US6-1 --- sphingomonads --- RNA-seq --- N-acyl-l-homoserine lactone --- ppGpp --- selenium --- selenocysteine --- selenoproteins --- selenocysteine insertion sequence --- nonsense-mediated decay --- G-quadruplex --- transcriptional regulation --- promoter --- CRISPR/Cas9 --- PRDM gene family --- TCGA data analysis --- somatic mutations --- transcriptome profiling --- human malignancies --- tristetraprolin (TTP) --- tumorigenesis --- posttranscriptional regulation --- adenosine and uridine-rich elements (AREs) --- circRNA-disease associations --- pathway --- heterogeneous network --- Patau Syndrome --- cytogenetics --- FOXO1 --- transcription factor --- molecular pathways --- bioinformatics --- molecular docking --- and drug design --- transcription regulation --- gene expression --- causal inference --- enhancer activity --- insect --- transcription factors --- structures and functions --- research methods --- progress and prospects --- Pax3 --- Pteria penguin (Röding, 1798) --- tyrosinase --- melanin --- RNA interference --- liquid chromatograph-tandem mass spectrometer (LC-MS/MS) --- epigenetics --- gene expression --- nutrition --- transcription --- disorders --- mechanisms --- Crassostrea gigas --- Pacific oyster --- pediveliger larvae --- bioadhesive --- transcriptome --- gene expression --- interactome --- microscopy --- fertilization --- self-incompatibility --- transcriptome --- tea --- long non-coding RNAs --- cancer --- acute leukemia --- therapeutic targets --- Adiponectin --- cancer --- Adiponectin receptors --- obesity --- inflammatory response --- inflammation --- nutritional status --- n/a

Image Processing Using FPGAs

Author:
ISBN: 9783038979180 / 9783038979197 Year: Pages: 204 DOI: 10.3390/books978-3-03897-919-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Computer Science
Added to DOAB on : 2019-06-26 08:44:06
License:

Loading...
Export citation

Choose an application

Abstract

This book presents a selection of papers representing current research on using field programmable gate arrays (FPGAs) for realising image processing algorithms. These papers are reprints of papers selected for a Special Issue of the Journal of Imaging on image processing using FPGAs. A diverse range of topics is covered, including parallel soft processors, memory management, image filters, segmentation, clustering, image analysis, and image compression. Applications include traffic sign recognition for autonomous driving, cell detection for histopathology, and video compression. Collectively, they represent the current state-of-the-art on image processing using FPGAs.

The Psychosocial Implications of Disney Movies

Author:
ISBN: 9783038978480 / 9783038978497 Year: Pages: 246 DOI: 10.3390/books978-3-03897-849-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Philosophy
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

In this volume of 15 articles, contributors from a wide range of disciplines present their analyses of Disney movies and Disney music, which are mainstays of popular culture. The power of the Disney brand has heightened the need for academics to question whether Disney’s films and music function as a tool of the Western elite that shapes the views of those less empowered. Given its global reach, how the Walt Disney Company handles the role of race, gender, and sexuality in social structural inequality merits serious reflection according to a number of the articles in the volume. On the other hand, other authors argue that Disney productions can help individuals cope with difficult situations or embrace progressive thinking. The different approaches to the assessment of Disney films as cultural artifacts also vary according to the theoretical perspectives guiding the interpretation of both overt and latent symbolic meaning in the movies. The authors of the 15 articles encourage readers to engage with the material, showcasing a variety of views about the good, the bad, and the best way forward.

Keywords

content analysis --- cultivation --- Disney --- family --- family structure --- family function --- Elsa --- Kristoff --- Olaf --- Marshmallow --- Let it Go --- enchantment --- applause --- engagement ring --- diamond --- gender --- snowmen --- wedding toast --- bullroarer --- fireworks --- witches --- magic --- standing ovation --- fertility --- parthenogenesis --- gender nonconformity --- non-binary --- storms --- family jewels --- snowflake --- feminism --- Moana --- Disney --- music --- colonialism --- imperialism --- appropriation --- Polynesia --- Disney --- EPCOT --- music --- appropriation --- world --- park --- entertainment --- sounds --- cultures --- Disney --- princess --- gender roles --- stereotyping --- children’s media --- death --- children --- Disney --- coping mechanisms --- Africana --- alternative royals --- intersectionality --- matrix of domination --- Disney --- gender --- motherhood --- media criticism --- family roles --- masculinity --- empowered mothering --- Pixar --- Disney --- postfeminism --- masculinity --- gender --- cultural studies --- Dumbo --- Lilo &amp --- Stitch --- Disney --- queer --- mean girls --- boobs and boyfriends --- girl cartoon --- gender --- pink elephants --- commodification --- Walter Benjamin --- diversity --- hegemony --- Disney --- coloniality --- adaptation --- Disney --- gender --- feminism --- political economy of film --- feminist film criticism --- feminist political economy of media --- gender stereotypes --- sexuality --- heroism --- hypermasculinity --- selflessness --- Hercules --- Zeus --- Megara --- Disney --- princess --- prince --- gender roles --- content coding analysis --- children’s media --- Disney --- girls --- beauty --- transnational media --- princess

Molecular Computing and Bioinformatics

Authors: --- ---
ISBN: 9783039211951 / 9783039211968 Year: Pages: 390 DOI: 10.3390/books978-3-03921-196-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Biotechnology
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

This text will provide the most recent knowledge and advances in the area of molecular computing and bioinformatics. Molecular computing and bioinformatics have a close relationship, paying attention to the same object but working towards different orientations. The articles will range from topics such as DNA computing and membrane computing to specific biomedical applications, including drug R&D and disease analysis.

Keywords

prostate cancer --- Mycoplasma hominis --- endoplasmic reticulum --- systems biology --- protein targeting --- biomedical text mining --- big data --- Tianhe-2 --- parallel computing --- load balancing --- bacterial computing --- bacteria and plasmid system --- Turing universality --- recursively enumerable function --- miRNA biogenesis --- structural patterns --- DCL1 --- protein–protein interaction (PPI) --- clustering --- protein complex --- penalized matrix decomposition --- avian influenza virus --- interspecies transmission --- amino acid mutation --- machine learning --- Bayesian causal model --- causal direction learning --- K2 --- brain storm optimization --- line graph --- Cartesian product graph --- join graph --- atom-bond connectivity index --- geometric arithmetic index --- P-glycoprotein --- efflux ratio --- in silico --- machine learning --- hierarchical support vector regression --- absorption --- distribution --- metabolism --- excretion --- toxicity --- image encryption --- chaotic map --- DNA coding --- Hamming distance --- Stenotrophomonas maltophilia --- iron acquisition systems --- iron-depleted --- RAST server --- NanoString Technologies --- siderophores --- gene fusion data --- gene susceptibility prioritization --- evaluating driver partner --- gene networks --- drug-target interaction prediction --- machine learning --- drug discovery --- microRNA --- environmental factor --- structure information --- similarity network --- bioinformatics --- identification of Chinese herbal medicines --- biochip technology --- DNA barcoding technology --- DNA strand displacement --- cascade --- 8-bit adder/subtractor --- domain label --- Alzheimer’s disease --- gene coding protein --- sequence information --- support vector machine --- classification --- adverse drug reaction prediction --- heterogeneous information network embedding --- stacking denoising auto-encoder --- meta-path-based proximity --- Panax ginseng --- oligopeptide transporter --- flowering plant --- phylogeny --- transcription factor --- multiple interaction networks --- function prediction --- multinetwork integration --- low-dimensional representation --- dihydrouridine --- nucleotide physicochemical property --- pseudo dinucleotide composition --- RNA secondary structure --- ensemble classifier --- diabetes mellitus --- hypoxia-inducible factor-1? --- angiogenesis --- bone formation --- osteogenesis --- protein transduction domain --- membrane computing --- edge detection --- enzymatic numerical P system --- resolution free --- molecular computing --- molecular learning --- DNA computing --- self-organizing systems --- pattern classification --- machine learning --- laccase --- Brassica napus --- lignification --- stress --- molecular computing --- bioinformatics --- machine learning --- protein --- DNA --- RNA --- drug --- bio-inspired

Regulatory microRNA

Authors: ---
ISBN: 9783038977681 9783038977698 Year: Pages: 348 DOI: 10.3390/books978-3-03897-769-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Genetics
Added to DOAB on : 2019-04-25 16:37:17
License:

Loading...
Export citation

Choose an application

Abstract

This book includes updated information about microRNA regulation, for example, in the fields of circular RNAs, multiomics analysis, biomarkers and oncogenes. The variety of topics included in this book reaffirms the extent to which microRNA regulation affects biological processes. Although microRNAs are not translated to proteins, their importance for biological processes is not less than proteins. An understanding of their roles in various biological processes is critical to understanding gene function in these biological processes. Although non-coding RNAs other than microRNAs have recently come under investigation, microRNA still remains the front runner as the subject of genetic and biological studies. In reading the collection of papers, readers can grasp the most updated information regarding microRNA regulation, which will continue to be an important topic in genetics and biology.

Keywords

tensor decomposition --- miRNA transfection --- sequence-nonspecific off-target regulation --- extracellular vesicles --- cancer --- therapeutics --- miRNA --- virus --- host --- Cross-Kingdom --- target prediction --- microRNAs --- autophagy --- mitophagy --- cardiac diseases --- biomarker --- calf --- Ileum --- miRNA-mRNA integration --- miRNA sequencing --- growth --- development --- microRNA --- myelodysplastic syndromes --- acute myeloid leukemia --- azacitidine --- 14q32 --- MEG3 --- autophagy regulator --- transcriptional factor --- non-coding RNA --- regulatory network --- RWR algorithm --- circular RNA --- circFGFR2 --- FGFR2 --- miR-133a-5p --- miR-29b-1-5p --- skeletal muscle --- proliferation --- differentiation --- breast cancer --- CAFs --- estrogens --- GPER --- miR-338-3p --- c-Fos --- Cyclin D1 --- amyotrophic lateral sclerosis (ALS) --- biomarker --- microRNA --- cerebrospinal fluid (CSF) --- muscle biopsy --- circulating miRNAs --- RNA interference --- small interfering RNA --- microRNA --- oncolytic virotherapy --- conditionally replicating adenovirus (CRAd) --- biomarker --- gene --- microRNA --- parkinson’s disease --- miRNA --- bioinformatic analysis --- ischemic stroke --- miRNA-gene target interaction --- network --- biomarker --- diagnosis --- prognosis --- microRNAs --- epigenetic biomarker --- sepsis --- inflammation --- Teleostei --- embryogenesis --- tissue-enriched miRNAs --- post-transcriptional gene regulation --- miRNA expression and regulation --- passenger miRNA --- biomarker --- vascular injury --- smooth muscle cells --- porcine vein graft and stent models --- bone angiogenesis --- osteogenesis --- angiogenic-osteogenic coupling --- microRNAs --- bone regeneration --- bone formation --- bone tissue-engineering --- angiomiRs --- osteomiRs --- hypoxamiRs --- circular RNA --- circHIPK3 --- microRNA --- miR-30a-3p --- skeletal muscle --- proliferation --- differentiation

The Future of Hyperspectral Imaging

Author:
ISBN: 9783039218226 / 9783039218233 Year: Pages: 220 DOI: 10.3390/books978-3-03921-823-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 16:39:37
License:

Loading...
Export citation

Choose an application

Abstract

Keywords

hyperspectral imaging --- Raman --- fluorescence --- sorting --- quality control --- black polymers --- PZT --- classification --- machine learning --- alternating direction method of multipliers --- Cramer–Rao lower bound --- forward observation model --- linear mixture model --- maximum likelihood --- multiband image fusion --- total variation --- fingerprints --- blood detection --- age determination --- hyperspectral imaging --- lossless compression --- multitemporal hyperspectral images --- information theoretic analysis --- predictive coding --- hyperspectral imaging --- plant phenotyping --- disease detection --- spectral tracking --- time series --- hyperspectral imaging --- principal component analysis --- oxygen saturation --- wound healing --- diabetic foot ulcer --- Raman spectroscopy --- chemical imaging --- compressive detection --- spatial light modulators (SLM) --- digital micromirror device (DMD) --- digital light processor (DLP) --- optimal binary filters --- Chemometrics --- multivariate data analysis --- compressive sensing --- hyperspectral imaging --- multiplexing system --- liquid crystal --- three-dimensional imaging --- integral imaging --- remote sensing --- point target detection --- CS-MUSI --- hyperspectral --- video --- imaging --- coastal dynamics --- moving vehicle imaging --- bi-directional reflectance distribution function (BRDF) --- hemispherical conical reflectance factor (HCRF) --- stereo imaging --- digital elevation model --- Virginia Coast Reserve Long Term Ecological Research (VCR LTER) --- Hyperspectral imaging --- painting samples --- retouching pigments --- watercolours --- multivariate analysis --- potatoes --- sprouting --- primordial leaf count --- hyperspectral imaging --- spectroscopy --- fusion --- wavelength selection --- PLSR --- interval partial least squares --- deep learning --- hyperspectral imaging --- neural networks --- machine learning --- image processing --- hyperspectral imaging --- medical imaging by HSI --- HSI for biology --- remote sensing --- hyperspectral microscopy --- fluorescence hyperspectral imaging --- Raman hyperspectral imaging --- infrared hyperspectral imaging --- statistical methods for HSI --- hyperspectral data mining and compression --- statistical methods for HSI --- hyperspectral data mining and compression

Listing 1 - 9 of 9
Sort by
Narrow your search

Publisher

MDPI - Multidisciplinary Digital Publishing Institute (9)


License

CC by-nc-nd (9)


Language

eng (9)


Year
From To Submit

2019 (9)