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The Origin and Early Evolution of Life: Prebiotic Chemistry of Biomolecules

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ISBN: 9783039216062 / 9783039216079 Year: Pages: 288 DOI: 10.3390/books978-3-03921-607-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:16
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Studying the origin of life is one of man’s greatest achievements over the last sixty years. The fields of interest encompassed by this quest are multiple and interdisciplinary: chemistry, physics, biology, biochemistry, mathematics, geology but also statistics, atmospheric science, meteorology, oceanography, and astrophysics. Recent scientific discoveries, such as water on Mars and the existence of super-Earths with atmospheres similar to primordial Earth, have pushed researchers to simulate prebiotic conditions in explaining the abiotic formation of molecules essential to life. This collection of articles offers an overview of recent discoveries in the field of prebiotic chemistry of biomolecules, their formation and selection, and the evolution of complex chemical systems.

Keywords

origin of life --- systems chemistry --- Chemomimesis --- Molecular Darwinism --- origin of life --- prebiotic chemistry --- thiol-rich peptides --- cysteine --- aminonitriles --- imidazoles --- origin of life --- prebiotic chemistry --- nucleotide and nucleoside synthesis --- protein design --- novel metalloproteins --- binary patterned amino acid sequences --- prebiotic chemistry --- population growth --- replication --- growth order --- Darwinian evolution --- selection --- origin of life --- abiogenesis --- carbon fixation --- hydrothermal vents --- electrochemistry --- reduction --- digit multiplicity --- information --- transmission --- encoding --- translation --- diversity --- function --- origin of life --- layered double hydroxide (LDH) clay --- pentose diphosphate --- pentopyranose nucleic acid --- arabinopyranose nucleic acid --- RNA --- base pairing --- purine precursor --- inosine --- AICAR --- peptide/RNA world --- prebiotic information system --- translation and the genetic code --- bridge peptide and aaRS --- ribozyme and tRNA --- tRNA and mRNA --- coevolution of translation machine and the genetic code --- MVC architecture pattern and biological information --- numerical codons --- AnyLogic software for computer simulation of translation machine --- phosphoryl transfer --- metabolism --- energy currency --- mixed anhydride --- origin of life --- hypercycle --- Monte Carlo --- prebiotic chemistry --- carbamic acid --- carbon dioxide-ammonia ices --- infrared spectra --- anharmonicity --- origin of life --- metabolism --- phosphates --- network expansion simulation --- thermodynamic bottleneck --- molecular clocks --- ab initio molecular dynamics --- catalysis --- prebiotic soup --- origins of life --- aldol reaction --- mechanochemistry --- minerals --- monosaccharides --- prebiotic chemistry --- prebiotic polymerization --- nucleotide oligomerization --- abasic oligomers --- nucleotide stability --- stability as a selection pressure --- dry-wet cycles --- genetic code origin --- tRNA accretion model --- tRNA-synthetase --- metabolism --- thioester --- nucleotidyltransferases --- early peptides --- ribosome --- n/a

Energy Storage and Management for Electric Vehicles

Authors: --- ---
ISBN: 9783039218622 / 9783039218639 Year: Pages: 238 DOI: 10.3390/books978-3-03921-863-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Technology (General)
Added to DOAB on : 2020-01-30 16:39:46
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This Special Edition of Energies on “Energy Storage and Management for Electric Vehicles” draws together a collection of research papers that critically evaluates key areas of innovation and novelty when designing and managing the high-voltage battery system within an electrified powertrain. The addressed topics include design optimisation, mathematical modelling, control engineering, thermal management, and component sizing.

Keywords

zinc–nickel single-flow battery --- equivalent circuit model --- self-discharge --- dynamic flow rate optimization --- genetic algorithm --- hybrid power system --- electric vehicle --- rule-based optimal strategy --- dynamic programming approach --- thermal modelling --- thermal behaviour --- lithium titanate oxide batteries --- optimal control --- supercapacitors --- batteries --- fuel cell --- hybrid vehicle --- battery degradation --- battery energy storage system --- charging scheme --- efficiency --- electric vehicle --- linear programming --- lithium ion battery --- operating expenses --- residential battery storage --- vehicle-to-building --- supercapacitor models --- parameter estimation --- ECE15 --- HPPC --- Simulink --- Simscape --- Matlab --- Identification --- regenerative energy --- timetable optimization --- energy storage system --- ?-constraint method --- improved artificial bee colony --- lithium-ion battery --- equivalent circuit model --- recursive least square --- adaptive forgetting factor --- parameter identification --- energy storage ageing and degradation --- life cycle assessment --- second-life energy storage applications --- Li-Sulfur batteries --- lithium-ion battery --- cell sorting --- multi-parameters sorting --- principal component analysis --- self-organizing maps clustering --- battery charging --- cycle-life --- state-of-health (SOH) --- battery cycle-life extension --- nonlinear battery model --- state of charge estimation --- lithium-ion battery --- Lipschitz nonlinear system --- Luenberger observer

There is a Crack in Everything—Education and Religion in a Secular Age

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ISBN: 9783039212774 / 9783039212781 Year: Pages: 266 DOI: 10.3390/books978-3-03921-278-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-12-09 16:39:37
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There are two constants in academic and theological discourse throughout history, they are the debate around secularization and the dialogue concerning the intersection of religion and education. Each age has had its debate about modernizing forces that drive concerns of impending secularization. In this publication this theme is approached from perspectives of teachers, of students, of policy makers and situated in a politico-historical context. Aware of the fact that in today’s plural societies one sacred canopy is non-existent anymore, cracks of the sacred canopy/canopies are described, as well as ‘the light that gets in’, the possible and challenging ways out are roughly sketched. We expect that each of the contributions of scholars of the East and the West, of the North and the South, and their presented examples and case studies, will stimulate the ongoing exploration and elaboration on the relationship between education and religion in todays’ and the coming world – work-in-progress for coming generations.

Keywords

religious education --- secularization --- pluralism --- non-confessional --- classroom observation --- ethnography --- Christian --- university --- radicalization --- post-secular --- secular --- religion education --- secularity --- secularism --- religion in public life --- representation of religion --- Bible --- Qur’an --- Ubuntu --- orthodoxy --- orthokardia --- orthopraxis --- Weltanschauung --- inter-worldview education --- Europe --- tolerance --- inequality --- power --- state Jewish religious education --- state Jewish secular education --- state Arab Moslem education --- state Christian education --- state Druze education --- religious and heritage education --- citizenship education --- religious minorities --- secularism --- Muslim --- youth --- immigration --- social boundaries --- identification --- college --- Québec --- inclusion --- worldview education --- universal design for learning --- learning in the presence of the other --- reflexive inclusion --- secularization --- rationality --- medicine --- theology --- symbiotic relevance --- school identity --- secularization --- secondary education --- teachers --- worldviews --- morality --- spirituality --- religion --- religious education --- life-as --- subjective-life --- secularism --- religious education --- values education --- strong religious schools --- Dutch Bible Belt --- citizenship education --- religious education --- liberal society --- secularization --- symbolic language --- philosophy of life --- religious sources of meaning --- metaphoric sensitivity --- inventive imagination --- role playing/bibliodrama --- identity construction --- life orientation --- bibliodrama --- narratives --- interreligious encounters --- education --- image of imams --- secularization --- plurality --- spiritual religiosity --- popular religiosity --- radicalization --- n/a --- n/a

Measures of Spirituality/Religiosity—Description of Concepts and Validation of Instruments

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ISBN: 9783038977582 9783038977599 Year: Pages: 148 DOI: 10.3390/books978-3-03897-759-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-04-25 16:37:17
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Why do we need more questionnaires to measure aspects of spirituality/religiosity when we already have so many well-tried instruments in use? One answer is that research in this field is growing and that new research questions continuously do arise. Several of these new questions cannot be easily answered with the instruments designed for previous questions. The field is expanding and, consequently, the research topics. Meanwhile several multidimensional instruments were developed which cover existential, prosocial, religious and non-religious forms of spirituality, hope, peace and trust&mdash;and several more. The &lsquo;disadvantage&rsquo; of these instruments is the fact that some are conceptually broad and often rather unspecific, but they might be suited quite well for culturally and spiritually diverse populations when the intention is to compare such diverse groups. This is the reason why more research on new instruments is needed as can be found in this Special Issue, and to stimulate a critical debate about their pros and cons.

Possible Scenarios for Homochirality on Earth

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ISBN: 9783039217229 / 9783039217236 Year: Pages: 318 DOI: 10.3390/books978-3-03921-723-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General)
Added to DOAB on : 2019-12-09 11:49:16
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In 1978, Fred Hoyle proposed that interstellar comets carrying several viruses landed on Earth as part of the panspermia hypotheses. With respect to life, the origin of homochirality on Earth has been the greatest mystery because life cannot exist without molecular asymmetry. Many scientists have proposed several possible hypotheses to answer this long-standing L-D question. Previously, Martin Gardner raised the question about mirror symmetry and broken mirror symmetry in terms of the homochirality question in his monographs (1964 and 1990). Possible scenarios for the L-D issue can be categorized into (i) Earth and exoterrestrial origins, (ii) by-chance and necessity mechanisms, and (iii) mirror-symmetrical and non-mirror-symmetrical forces as physical and chemical origins. These scenarios should involve further great amplification mechanisms, enabling a pure L- or D-world.

Keywords

chirogenesis --- enantiomorphism --- nepheline --- magmatic flow --- etch figures --- origin of life --- biological homochirality --- deracemization --- super-high-velocity impact --- plasma reactor --- absolute asymmetric synthesis --- amino acids --- origin of life --- amino acid handedness --- nucleus–molecular coupling --- chirality --- circularly polarized luminescence --- circular dichroism --- symmetry breaking --- parity violation --- weak neutral current --- tunneling --- Z0 boson --- homochirality --- precision measurement --- homochirality --- circularly polarized light --- asymmetric reaction --- polymer --- ?-strand --- hidden chirality --- two-fold helix --- multi-point approximation --- tilt-chirality --- high dimensional chirality --- spin polarized electrons --- homochirality --- magnetism --- prebiotic --- environmental chirality --- C1- and C2-symmetric catalysts --- chiral field (memory) --- racemic field --- Viedma ripening effect --- Wallach’s rule --- heat capacity --- metal-organic framework --- triethylenediamine (DABCO) molecules --- racemate --- Salam hypothesis --- homochirality --- parity violation --- neutrinos --- gravitation --- enantiomer self-disproportionation --- SDE --- achiral stationary phase --- homochiral and heterochiral aggregates --- chiral separation --- chirality --- genesis of life chirality --- asymmetric autocatalysis --- homochirality --- chirality --- asymmetric synthesis --- Soai reaction --- biological homochirality --- enantioselective reaction --- autocatalysis --- origin of life --- replicators --- bioorganic homochirality --- circularly polarized photon --- spin-polarized lepton --- parity violation in the weak interaction --- symmetry breaking --- assemblies --- supramolecular chirality --- homochirality --- self-assembly --- vortex --- lipid --- supramolecular assembly --- symmetry breaking --- homochirality

Long-Term Health Effects of the 9/11 Disaster

Authors: --- ---
ISBN: 9783039218127 / 9783039218134 Year: Pages: 298 DOI: 10.3390/books978-3-03921-813-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Philosophy
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The terrorist attacks on the World Trade Center towers on September 11, 2001, also referred as 9/11, was an iconic event in US history that altered the global and political response to terrorism. The attacks, which involved two planes hitting the twin towers in Lower Manhattan, New York City, resulted in the collapse of the buildings and over 2800 deaths of occupants of the buildings, fire, police and other responders and persons on the street in the vicinity of the collapsing buildings. The destroyed towers and the surrounding buildings have since been replaced but the health effects that resulted from the release of tons of dust, gases and debris as well as the life threat trauma are ongoing, and represent a major health burden among persons directly exposed. Hundreds of scientific publications have documented the physical and mental health effects attributed to the disaster. The current state-of-the-art in understanding the ongoing interactions of physical and mental health, especially PTSD, and the unique mechanisms by which pollutants from the building collapse, have resulted in long term pulmonary dysfunction, course of previously reported conditions, potential emerging conditions (e.g., heart disease and autoimmune diseases), as well as quality of life, functioning and unmet health care needs would be in the purview of this Special Issue on the 9/11 Disaster.

Keywords

counseling --- post-disaster --- psychotherapy --- mental health treatment --- treatment utilization --- World Trade Center --- indoor allergens sensitization --- asthma quality of life --- asthma control --- asthma outcomes --- mini asthma quality of life questionnaire --- asthma morbidity --- WTC-related asthma --- immunoglobulin E --- allergen exposure --- WTC attack --- respiratory symptoms --- lower Manhattan residents --- cleaning practices --- WTC --- fibrotic sarcoid --- injury --- inflammation --- fibrosis --- World Trade Center disaster --- pulmonary fibrosis --- dust --- injury --- physical health --- mental health --- World Trade Center disaster --- Short Form-12 (SF-12) --- HQoL --- 9/11 --- 9/11 disaster --- handgrip strength --- WTC responders --- PTSD --- depression --- aging --- 9/11 impact --- retirement --- chronic disease --- PTSD --- disaster --- income loss --- PTSD symptom change --- PCL score --- longitudinal analysis --- PTSD cluster --- WTC survivors --- 9/11 disaster --- obstructive sleep apnea --- comorbid insomnia --- sleep-related quality of life --- chronic sinusitis --- sleepiness --- WTC responders --- thyroid cancer --- 9/11 disaster --- World Trade Center --- surveillance bias --- sarcoidosis --- World Trade Center (WTC) --- Scadding stage --- lung function --- severe lung disease --- extrathoracic sarcoidosis --- cardiac sarcoidosis --- unmet mental health care needs --- Asian Americans --- World Trade Center attack --- disaster --- mental health conditions --- mental health service use --- health insurance --- social support --- stressful life events --- cognitive reserve --- cognitive decline --- latent class analysis --- disaster epidemiology --- PTSD --- airway physiology --- dust --- environmental health --- forced oscillation --- respiratory function --- small airway disease --- paresthesia --- neuropathic symptoms --- Cox regression --- hazard function --- World Trade Center exposure --- metabolic syndrome --- airway hyperreactivity --- World Trade Center --- disaster mental health --- evidence-based treatment --- mental health service utilization --- quality improvement --- 9/11 --- screening --- thyroid cancer --- biomarkers --- medical imaging --- pulmonary function tests --- lung injury --- occupational exposure --- epidemiological studies --- peripheral neuropathy --- prevalence --- World Trade Center --- rescue/recovery workers --- occupational exposure --- sarcoidosis --- World Trade Center --- 9/11 --- genetics --- firefighters --- FDNY --- 9/11 disaster --- asthma --- trigger(s) --- air pollution --- irritant(s) --- health-related quality of life --- n/a

New Research in Obsessive-Compulsive Disorder and Major Depression

Authors: ---
ISBN: 9783039210909 / 9783039210916 Year: Pages: 102 DOI: 10.3390/books978-3-03921-091-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Psychology
Added to DOAB on : 2019-06-26 08:44:07
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Major depression and obsessive–compulsive disorder (OCD) are now recognized among the most frequent psychiatric disorders, affecting 16–17% and 2–3% of the general population, respectively. They are commonly characterized by: i) a high level of psychiatric and somatic comorbidities; ii) a recurrence or chronic profile; and iii) a negative impact on daily functions, thereby leading to a profound impairment of quality of life. Despite significant advances in pharmacological and psychological therapies over the last decades, unsuccessful responses to standard treatment strategies are classically observed in approximately 20–30% of cases. Therefore, there is a significant need for improving the pathophysiological knowledge through a better identification of environmental, clinical, psychological, genetic, anatomical, and biological determinants, specifically implied in the development, the phenotypic expression, and the relapsing course and/or contributing to the therapeutic failure in major depression and OCD. We are convinced that this research approach is particularly relevant providing critical support for the promotion of innovative treatment alternatives potentially useful for the management of resistant forms of major depression and OCD.

Abiotic Stress Effects on Performance of Horticultural Crops

Authors: ---
ISBN: 9783039217502 / 9783039217519 Year: Volume: 1 Pages: 126 DOI: 10.3390/books978-3-03921-751-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Agriculture (General)
Added to DOAB on : 2019-11-05 10:43:33
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Horticultural crop yield and quality depend on genotype, environmental conditions, and production management. In particular, adverse environmental conditions may greatly affect crop performance, reducing crop yield by 50%–70%. Abiotic stresses such as cold, heat, drought, flooding, salinity, nutrient deficiency, and ultraviolet radiation affect multiple physiological and biochemical mechanisms in plants as they attempt to cope with the stress conditions. However, different crop species can have different sensitivities or tolerances to specific abiotic stresses. Tolerant plants may activate different strategies to adapt to or avoid the negative effect of abiotic stresses. At the physiological level, photosynthetic activity and light-use efficiency of plants may be modulated to enhance tolerance against the stress. At the biochemical level, several antioxidant systems may be activated, and many enzymes may produce stress-related metabolites to help avoid cellular damage, including compounds such as proline, glycine betaine, and amino acids. Within each crop species there is a wide variability of tolerance to abiotic stresses, and some wild relatives may carry useful traits for enhancing the tolerance to abiotic stresses in their progeny through either traditional or biotechnological breeding. The research papers and reviews presented in this book provide an update of the scientific knowledge of crop interactions with abiotic stresses.

Safety and Microbiological Quality

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ISBN: 9783039214914 / 9783039214921 Year: Pages: 126 DOI: 10.3390/books978-3-03921-492-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Microbiology
Added to DOAB on : 2019-12-09 11:49:15
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The safety and microbiological quality of fermented foods covers complementary aspects of such products. Food fermentation is primary intended to improve food preservation, thereby modifying food properties. However, the management of chemical and microbiological hazards is a leading aspect for innovative processing in this domain. Similarly, microbiological quality in fermented foods is of peculiar importance: all microorganisms with a positive effect, including probiotic bacteria, fermentative bacteria, Saccharomyces and non-Saccharomyces yeasts, can be relevant. The fitness of pro-technological microorganisms impacts nutritional quality, but also sensory properties and processing reliability. This book provides a broad view of factors which determine the safety and microbiological quality of fermented foods. A focus is made on the interconnection between starter properties and the expectations related to a probiotic effect. All chapters underline the involvement of fermented foods towards better resource management and increasing food and nutritional security, especially in developing countries.

Exploring the Future of Christian Monasticisms

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ISBN: 9783039280247 / 9783039280254 Year: Pages: 138 DOI: 10.3390/books978-3-03928-025-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2020-01-30 16:39:46
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The institution of monasticism in the Christian Church is in general decline, at least in so-called “first world” nations. Though there are many reasons for this, monastic leaders are confronted by the reality of fewer communities, monks, and nuns nonetheless. At the same time, many younger Christians are rediscovering the rich heritage of the monastic tradition. Though they themselves might not be called to join a traditional monastery, they are eager to appropriate monastic practices in their own lives. This had led to a movement known as the “new monasticism” or “secular monasticism.” Despite lacking a unified vision and any central organization, these new/secular monastics are attempting, in their own ways, to carry on the tradition and practices of Christian monasticism. As well, there is a movement within historical Christian monasteries to pour new wine into old wineskins. Traditional forms of monasticism are also generally flourishing in developing nations, breathing new life into monasticism. This volume looks at the current monastic landscape to assess where monasticism stands and to imagine ways in which it will grow in the future, leading not only to a renewed Christian monasticism but to new monasticisms.

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