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Human Challenge Studies in Endemic Settings

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Book Series: SpringerBriefs in Ethics ISBN: 9783030414801 Year: Pages: 134 DOI: 10.1007/978-3-030-41480-1 Language: English
Publisher: Springer Nature
Subject: Biology --- Internal medicine --- Medicine (General) --- History --- Migration
Added to DOAB on : 2020-09-23 00:06:25
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This open access book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide. HCS are widely considered to be an especially promising approach to vaccine development, including for pathogens endemic to LMICs. However, challenge studies are sometimes controversial and raise complex ethical issues, some of which are especially salient in endemic and/or LMIC settings. Informed by qualitative interviews with experts in infectious diseases and bioethics, this book highlights areas of ethical consensus and controversy concerning this kind of research. As the first volume to focus on ethical issues associated with human challenge studies, it sets the agenda for further work in this important area of global health research; contributes to current debates in research ethics; and aims to inform regulatory policy and research practice. Insofar as it focuses on HCS in (endemic) settings where diseases are present and/or widespread, much of the analysis provided here is directly relevant to HCS involving pandemic diseases including COVID19.

Exploring the Future of Christian Monasticisms

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ISBN: 9783039280247 9783039280254 Year: Pages: 138 DOI: 10.3390/books978-3-03928-025-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2020-01-30 16:39:46
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The institution of monasticism in the Christian Church is in general decline, at least in so-called “first world” nations. Though there are many reasons for this, monastic leaders are confronted by the reality of fewer communities, monks, and nuns nonetheless. At the same time, many younger Christians are rediscovering the rich heritage of the monastic tradition. Though they themselves might not be called to join a traditional monastery, they are eager to appropriate monastic practices in their own lives. This had led to a movement known as the “new monasticism” or “secular monasticism.” Despite lacking a unified vision and any central organization, these new/secular monastics are attempting, in their own ways, to carry on the tradition and practices of Christian monasticism. As well, there is a movement within historical Christian monasteries to pour new wine into old wineskins. Traditional forms of monasticism are also generally flourishing in developing nations, breathing new life into monasticism. This volume looks at the current monastic landscape to assess where monasticism stands and to imagine ways in which it will grow in the future, leading not only to a renewed Christian monasticism but to new monasticisms.

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