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Animals and Medicine : The Contribution of Animal Experiments to the Control of Disease

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ISBN: 9782821876347 Language: English
Publisher: Open Book Publishers
Subject: Science (General)
Added to DOAB on : 2019-12-06 13:15:39
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Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives - both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine - from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer. This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

Improving outcomes in cerebral palsy with early intervention: new translational approaches

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195121 Year: Pages: 155 DOI: 10.3389/978-2-88919-512-1 Language: English
Publisher: Frontiers Media SA
Subject: Pediatrics --- Medicine (General) --- Neurology
Added to DOAB on : 2015-12-03 13:02:24
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The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life.CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry. CP may be viewed as aberrant plasticity in response to a lesion, indeed, abnormalities in movement are subtle at first but develop subsequently. It is misleading to suppose that developmental mechanisms are self-reparative. The challenge is to understand activitydependent fine tuning of neural circuitry during normal development and to find how to promote desirable plasticity whilst limiting undesirable effects following developmental lesions. However, before proposing interventions, we have to develop our ability to predict the severity of neonatal insults.We solicited a variety of articles, including long and short reviews, original research and opinion pieces, from both basic scientists and clinicians. Likewise we, as editors, have complementary knowledge and experience in this area. Anna Basu is an academic pediatric neurologist and Gavin Clowry is a developmental neuroscientist.

Creating Healthy and Sustainable Buildings

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ISBN: 9783030194123 Year: Pages: 160 DOI: 10.1007/978-3-030-19412-3 Language: English
Publisher: Springer Nature
Subject: Architecture --- Social Sciences --- Public Health
Added to DOAB on : 2020-02-05 11:21:08
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The open access book discusses human health and wellbeing within the context of built environments. It provides a comprehensive overview of relevant sources of literature and user complaints that clearly demonstrate the consequences of lack of attention to health in current building design and planning. Current designing of energy-efficient buildings is mainly focused on looking at energy problems and not on addressing health. Therefore, even green buildings that place environmental aspects above health issues can be uncomfortable and unhealthy, and can lead to public health problems. The authors identify many health risk factors and their parameters, and the interactions among risk factors and building design elements. They point to the need for public health specialists, engineers and planners to come together and review built environments for human wellbeing and environmental sustainability. The authors therefore present a tool for holistic decision-making processes, leading to short- and long-term benefits for people and their environment.

P5 eHealth: An Agenda for the Health Technologies of the Future

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ISBN: 9783030279943 Year: Pages: 189 DOI: 10.1007/978-3-030-27994-3 Language: English
Publisher: Springer Nature
Subject: Social Sciences --- Psychology --- Public Health --- Philosophy
Added to DOAB on : 2020-02-05 11:21:06
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This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.

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