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Biofilm-Based Nosocomial Infections

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ISBN: 9783038421351 9783038421368 Year: Pages: 238 DOI: 10.3390/books978-3-03842-136-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-05-12 12:14:31
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Microbial biofilms have been implicated in a large number of acute and chronic infections, as well as in the failure of antibiotic treatment, particularly in hospitalized patients. In fact, the well-known persistence in the nosocomial environment of multidrug resistant microorganisms is believed to be highly promoted by the ability of the great majority of the involved bacterial and fungal species to adhere on living or abiotic surfaces, and to grow in sessile mode, to form single- or multi-species biofilms. In these communities, microbes grow encased in a hydrated matrix of extracellular polymeric substances produced by themselves and are well protected from the host immune response and the attack of antimicrobial molecules. Thus, the establishment of microbial biofilm communities on the mucosal and soft tissues of hospitalized patients, as well as on the surfaces of indwelling devices and medical instruments, is expected to have a great influence on the success of the antibiotic therapies against most of the bugs involved in nosocomial infections, being biofilm-growing bacteria and fungi much less susceptible to antibiotics.

Long-Term Ecosystem Changes in Riparian Forests

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Book Series: Ecological Research Monographs ISBN: 9789811530098 Year: Pages: 234 DOI: 10.1007/978-981-15-3009-8 Language: English
Publisher: Springer Nature
Subject: Ecology --- Forestry --- Botany --- Environmental Sciences
Added to DOAB on : 2020-06-16 23:58:18
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This open access book presents and analyzes the results of more than 30 years of long-term ecological research in riparian forest ecosystems with the aim of casting light on changes in the dynamics of riparian forests over time. The research, focusing on the Ooyamazawa riparian forest, one of the remaining old-growth forests in Japan, has yielded a number of interesting outcomes. First, it shows that large-scale disturbances afford various trees opportunities for regeneration and are thus the driving force for the coexistence of canopy trees in riparian forests. Second, it identifies changes in reproductive patterns, highlighting that seed production has in fact quantitatively increased over the past two decades. Third, it describes the decline in forest floor vegetation caused by deer grazing and reveals how this decline has affected bird and insect populations. The book illustrates the interconnectedness of phenomena within an ecosystem and the resultant potential for cascade effects and also stresses the need for long-term ecological studies of climate change impacts on forests. It will be of interest to both professionals and academics in the field of forest science.

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