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Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino

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Book Series: Phármakon ISBN: 9788868870157 Year: Volume: 1 Pages: 767 DOI: 10.6093/978-88-6887-015-7
Publisher: FedOA - Federico II University Press
Subject: Therapeutics
Added to DOAB on : 2018-06-08 13:11:19
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For thousands of years, pharmacological knowledge coming from natural remedies, has been handed down from generation to generation, without any awareness of the ways in which preparations are made to face diseases. The advent of pharmaceutical chemistry and of the modern drug industry turned that lack of awareness into a scientific knowledge that changed the destiny of the human race. The twenty-eight chapters of this book, are taken from the lectures held by Professor Ettore Novellino every year in his course “Pharmaceutical Chemistry and Toxicology 2”. The first chapters address the basic notions of drugs, homeostasis, pharmacopoeia, and receptor; then, the different pharmaceutical classes are introduced by analyzing their pharmacological and chemical aspects. In particular, the structural study of the interaction between drugs and receptors or biological enzymes gives the fundamentals to connect the chemical and stereochemical properties of a compound family, with the biological activity, a correlation better known as Quantitative Structure-Activity Relationship (QSAR). Several examples of the synthesis of some of the most historically renown drugs, provided at the end of each chapter, integrate the book.

Mittelstaendische Unternehmen und Genossenschaftsbanken

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Book Series: Beitraege zum Controlling ISBN: 9783631593844 Year: Pages: 508 DOI: 10.3726/b13847 Language: German
Publisher: Peter Lang International Academic Publishing Group
Subject: Business and Management
Added to DOAB on : 2019-01-15 13:32:29
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Die Finanzierung über Bankkredite stellt in Deutschland die wichtigste Finanzierungsquelle für mittelständische Unternehmen dar. Aufgrund der zentralen Bedeutung der Bankfinanzierung, die z. T. zu einer enormen Abhängigkeit der Unternehmen von der Bank führt, stellt sich aus Unternehmersicht die Frage, durch welche Einflussfaktoren die zentralen Parameter des Kreditvertrags – der Zinssatz, die Sicherheitenstellung und die Kreditverfügbarkeit – determiniert werden. Ziel der Arbeit ist es zu untersuchen, ob aus verhaltenswissenschaftlichen Aspekten ökonomische Konsequenzen für das Unternehmen resultieren. Zu diesem Zweck wurde eine empirische Untersuchung bei Genossenschaftsbanken durchgeführt. Die Auswertungsergebnisse zeigen, dass verhaltenswissenschaftliche Elemente insgesamt einen erheblichen Erklärungsbeitrag, insbesondere für die Sicherheitenstellung und die Kreditverfügbarkeit, leisten können.

Ontologia relazionale. Ricerche sulla filosofia classica tedesca

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ISBN: 9788868870645 Year: Volume: 13 Pages: 156 DOI: 10.6093/978-88-6887-064-5 Language: Italian
Publisher: FedOA - Federico II University Press
Added to DOAB on : 2019-12-06 17:17:09
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The volume contains the proceedings of the conference on the subject of relational ontology, which involved a group of scholars of classical German philosophy with the aim of explaining the reasons, drawing inspiration and categories from the ideal and conceptual constellation of that age of culture. The idea from which they make the contributions is that for relational ontology we can understand a theory on the structure of reality (onto-logic), attentive to the development of the explanatory and normative potential of the category of reciprocity. The contributions thus define a path that, starting from Kant and the question of a unity and duplicity of the ego, passing through the consideration of the Fichtian relational ontology and the idea of a constitution of identity responding to the appeal from the other (on this theme a dialogue Ricoeur / Fichte is also staged), it touches on the notion of natural law of Schelling, to arrive at the Hegelian construction of an ontology and logic of the relationship, which can be found in the very notion of civil society, and finally to reading in a 'materialistic' key of Kantian transcendental idealism, in relation to the notion of reciprocal action.

Supply Chain Design

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Book Series: Bochumer Beitraege zur Unternehmensfuehrung ISBN: 9783631543757 Year: Pages: 265 DOI: 10.3726/b14025 Language: German
Publisher: Peter Lang International Academic Publishing Group
Subject: Economics --- Business and Management
Added to DOAB on : 2019-01-15 13:32:19
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Diese Arbeit wurde mit dem Ernst-Zander-Preis 2005 der Ruhr-Universität Bochum ausgezeichnet.
Das Supply Chain Design als strategisches Supply Chain Management beinhaltet als wesentlichen Aspekt die Konfiguration der Supply Chain. Dabei sind die über eine Preisminimierung hinausgehenden Auswahlkriterien der Zulieferer sowie die aus dem langfristigen Planungshorizont der Fragestellung resultierende Unsicherheit geeignet zu berücksichtigen. In dieser Arbeit werden die vielfältigen betriebswirtschaftlichen Aspekte des Supply Chain Design umfassend diskutiert und ein Kriterienkatalog zur Auswahl von Zulieferern entwickelt. Die Unsicherheit wird mit Hilfe des neu entwickelten Konzeptes der Zielrobustheit abgebildet. Die Planungsentscheidungen im Rahmen des Supply Chain Design können durch das vorgestellte Vorgehen unterstützt und in ihren Konsequenzen quantifiziert werden.

Als Andere unter Anderen

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Book Series: Edition Moderne Postmoderne ISBN: 9783839452455 Year: Pages: 260 DOI: 10.14361/9783839452455 Language: German
Publisher: transcript Verlag
Subject: Social Sciences
Added to DOAB on : 2020-08-04 23:59:19
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Pragmatic Philanthropy: Asian Charity Explained

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ISBN: 9789811071188 9789811071195 Year: Pages: 173 DOI: 10.1007/978-981-10-7119-5 Language: English
Publisher: Palgrave Macmillan Grant: The Centre for Asian Philanthropy and Society
Subject: Economics --- Sociology
Added to DOAB on : 2018-05-31 18:39:03
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This cutting edge text considers how Asian philanthropists and charitable organizations break with Western philanthropic traditions and examines the key traits and trends that make social investment in Asia unique. Based on 30 case studies of excellent social delivery organizations (SDOs) and social enterprises as well as interviews with ultra-high net-worth individuals throughout Asia, this book examines which characteristics and strategies lead to successful philanthropy and social delivery organizations. Providing evidence based findings on philanthropy, social investment and social delivery organizations in Asia, this book provides invaluable resources for those wishing to deepen their understanding of the sector and what this means for political and economic development in the region.

Arbeitsunfall 4.0

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Book Series: Studien aus dem Max-Planck-Institut für Sozialrecht und Sozialpolitik ISBN: 9783845295961 Year: Volume: 72 DOI: http://dx.doi.org/10.5771/9783845295961 Language: German
Publisher: Nomos Verlagsgesellschaft mbH & Co. KG
Subject: Social Sciences
Added to DOAB on : 2019-09-27 08:12:39
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Digitisation and tertiarisation have made it difficult to categorise activities as private or work-related. The two notions that have traditionally been used to make that distinction – i.e. place of work and working time – are losing their importance. An increasing number of employees are subject to the phenomenon of blurred boundaries: They set their own hours, work from home or on-the-go. German Social Accident Insurance, however, determines the question of coverage on the allocation of the accident to either the work sphere or the private sphere of the aggrieved party.The book explores the extent to which it is necessary to modernise the way risks are allocated in order to not discriminate against those who have jobs outside of traditional parameters and discusses whether it is still adequate to base allocation mechanisms on the principles of the employers’ business risk and duties of care. By way of extensive dogmatic analysis and a comparison with other systems of risk allocation, the study proposes a modern take on allocating risks with just results for both employers and employees from all fields of work.

An Introduction to Ethics in Robotics and AI

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Book Series: SpringerBriefs in Ethics ISBN: 9783030511104 Year: Pages: 117 DOI: 10.1007/978-3-030-51110-4 Language: English
Publisher: Springer Nature
Subject: Philosophy --- Computer Science --- Psychology
Added to DOAB on : 2020-09-01 00:01:21
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This open access book introduces the reader to the foundations of AI and ethics. It discusses issues of trust, responsibility, liability, privacy and risk. It focuses on the interaction between people and the AI systems and Robotics they use. Designed to be accessible for a broad audience, reading this book does not require prerequisite technical, legal or philosophical expertise. Throughout, the authors use examples to illustrate the issues at hand and conclude the book with a discussion on the application areas of AI and Robotics, in particular autonomous vehicles, automatic weapon systems and biased algorithms. A list of questions and further readings is also included for students willing to explore the topic further.

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