Search results: Found 67

Listing 1 - 10 of 67 << page
of 7
>>
Sort by
Folias Mitocondriais: Uma Breve Viagem Sobre a Energia da Vida

Authors: --- --- ---
Book Series: Outros Títulos ISBN: 9789892620039 Year: Pages: 56 DOI: 10.14195/978-989-26-2004-6 Language: Portuguese
Publisher: Coimbra University Press
Added to DOAB on : 2020-10-20 16:48:45
License:

Loading...
Export citation

Choose an application

Abstract

Comunicar através da banda desenhada pode constituir uma estratégia multifacetada eficiente. A narrativa desta banda desenhada transporta o leitor para uma abordagem realista, embora abreviada, da biologia da mitocôndria, em sintonia com a alteração nas rotinas diárias da Lara. Lara é uma paciente ficcionada com um problema metabólico, não conhecido, que assume a sua saúde nas suas próprias mãos, e que se interessa por metabolismo e mitocôndrias para compreender melhor os processos pelos quais os organismos vivos convertem os alimentos em energia, ao nível celular. Além disso, tem também como objetivo comunicar este fascinante mundo a amigos e pacientes, de tal forma que possa ser útil, também, a cientistas e ao público em geral. A banda desenhada intercala descobertas de personagens reais que contribuíram amplamente para o conhecimento das mitocôndrias, como o Peter Mitchell, o Hans Adolf Krebs e a Lynn Margulis, com personagens fictícias, como a Lara e o Jorge, diretamente associados

Pharmacokinetics and Drug Metabolism in Canada: The Current Landscape

Authors: ---
ISBN: 9783038427971 9783038427988 Year: Pages: VIII, 302 DOI: 10.3390/books978-3-03842-798-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2018-04-06 13:44:18
License:

Loading...
Export citation

Choose an application

Abstract

Canadian Pharmaceutical Scientists have a rich history of ground-breaking research in pharmacokinetics and drug metabolism undertaken throughout its Pharmacy and Medical Schools and within the Pharmaceutical and biotechnology industry. The principle of drug Absorption, Distribution, Metabolism and Excretion (ADME) is the foundational basis of rationale drug-design, and pharmacotherapy. The study of ADME and its descriptive quantitative analysis is the basis of pharmacokinetics. Pharmacokinetics is fundamental in the development of a new chemical entity into a marketable product and is essential in understanding the bioavailability, bioequivalence and biosimilarities of drugs. Pharmacokinetics and drug development studies facilitate an understanding of organ-based functionality. Population pharmacokinetic variability and the modeling of drug concentrations has significant utility in translating individual response in a target patient population.This special issue serves to highlight and capture the contemporary progress and current landscape of pharmacokinetics and drug metabolism within the prevailing Canadian context. We invite articles on all aspects of Pharmacokinetics and Drug Metabolism studies highlighting the world-class research currently undertaken in Canada for this special issue.

Functional and Bioactive Properties of Food

Authors: ---
ISBN: 9783038973546 9783038973553 Pages: 174 DOI: 10.3390/books978-3-03897-355-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Nutrition and Food Sciences --- Biology
Added to DOAB on : 2018-11-23 11:11:39
License:

Loading...
Export citation

Choose an application

Abstract

Diet and nutrition are key tools in promoting health and reducing the comorbidities of chronic diseases. There are thousands of biomolecules in fruits, vegetables, wild and medicinal plants, other land and marine organisms, which can exert functional and health-promoting effects through bioactivity beyond nutrition. From the enormous amount of knowledge generated from different natural bioactive ingredients present in foods, we are aiming to bring together experts working in different fields of food, nutrition, and health, in order to work on this Special Issue, with a comprehensive collection of papers to gain insight into the most promising bioactive compounds in different foods, to improve the preservation of bioactivity during the food processing chain, and to provide scientific evidence of the efficacy of key bioactives in foods in preventing disease and improving health and wellbeing.

Nutrition and Cancer

Author:
ISBN: 9783038428916 9783038428923 Year: Pages: VIII, 206 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Oncology --- Internal medicine
Added to DOAB on : 2018-06-22 11:04:15
License:

Loading...
Export citation

Choose an application

Abstract

The development and treatment of cancer presents a complex interaction between tumor and host. Provision of nutrients not only enables the maintenance of nutritional status, but also provides substrates and signals for immunity, tumor metabolism and protection of the host from treatment toxicities. Fat is one dietary element that has been explored for its role in cancer development. While the bulk of these studies have been observational or experimental, the evidence assembled suggests that dietary lipids behave uniquely to prevent or promote cancers. An additional aspect of cancer development is the role of adipose tissue as a source of, and a responder to, inflammatory signals that may be involved in tumor development. This Special Issue of Nutrients focuses on fat and cancer. The contributors to this Special Issue are well-recognized leaders in the field of cancer and have unique areas of focus including metabolism, immunology, biochemistry, epidemiology and nutrition. Each contribution highlights the latest research in these areas and what is known about fat and cancer with topics ranging from diet and cancer prevention, mechanisms of n-3 fatty acids on tumor development and the role of adipose tissue in cancer development and progression.

B-Vitamins and One-Carbon Metabolism

Author:
ISBN: 9783038429739 9783038429746 Year: Pages: XII, 390 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2018-06-26 13:22:55
License:

Loading...
Export citation

Choose an application

Abstract

Folate, vitamin B12, vitamin B6 and riboflavin play a key role as coenzymes in one-carbon metabolism which, in turn, is essential for a broad range of fundamental physiological processes, including RNA and DNA synthesis, cell division, tissue growth and methylation. Deficiencies or imbalance of B-vitamins, as well as genetic polymorphisms and environmental factors, are shown to disturb the normal function of one-carbon metabolism with adverse effects on human health. Although a vast volume of research has already been conducted in this area, there are still significant gaps in our knowledge that require further investigations. This Special Issue of Nutrients invited submission of manuscripts, original research or reviews of the scientific literature, focused on novel findings in relation to B-vitamins and one-carbon metabolism in terms of: metabolic roles and molecular mechanisms; gene–nutrient interactions; fetal growth and programing; risk of disease (birth defects and pregnancy related conditions, cancer, cardiovascular disease and hypertension, neuropsychiatric disease, osteoporosis); health effects of B-vitamin supplementation and food fortification.

DHA for Optimal Health

Author:
ISBN: 9783038429715 9783038429722 Year: Pages: X, 276 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Psychology
Added to DOAB on : 2018-06-26 16:08:39
License:

Loading...
Export citation

Choose an application

Abstract

This Special Issue of Nutrients, entitled "DHA for Optimal Health", consists of evidence-based original research or reviews of the scientific literature. Manuscripts focus on the evidence that underpins dietary requirements throughout the lifespan (from in-utero to the elderly) for optimal brain function and/or prevention (or treatment) of disease.

Plant Mitochondria

Author:
ISBN: 9783038975502 9783038975519 Year: Pages: 400 DOI: 10.3390/books978-3-03897-551-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Plant Sciences
Added to DOAB on : 2019-02-19 09:53:15
License:

Loading...
Export citation

Choose an application

Abstract

The primary function of mitochondria is respiration, where the catabolism of substrates is coupled to ATP synthesis via oxidative phosphorylation. In plants, mitochondrial composition is relatively complex and flexible and has specific pathways to support photosynthetic processes in illuminated leaves. Plant mitochondria also play important roles in a variety of cellular processes associated with carbon, nitrogen, phosphorus, and sulfur metabolism. Research on plant mitochondria has rapidly developed in the last few decades with the availability of the genome sequences for a wide range of model and crop plants. Recent prominent themes in plant mitochondrial research include linking mitochondrial composition to environmental stress responses, and how this oxidative stress impacts on the plant mitochondrial function. Similarly, interest in the signaling capacity of mitochondria, the role of reactive oxygen species, and retrograde and anterograde signaling has revealed the transcriptional changes of stress responsive genes as a framework to define specific signals emanating to and from the mitochondrion. There has also been considerable interest in the unique RNA metabolic processes in plant mitochondria, including RNA transcription, RNA editing, the splicing of group I and group II introns, and RNA degradation and translation. Despite their identification more than 100 years ago, plant mitochondria remain a significant area of research in the plant sciences. This Special Issue, “Plant Mitochondria”, will cover a selection of recent research topics and timely review articles in the field of plant mitochondrial research.

Comorbidity of Mental and Physical Disorders

Authors: --- ---
ISBN: 9783318026030 9783318026047 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103012
Subject: Public Health
Added to DOAB on : 2019-11-26 11:22:14
License:

Loading...
Export citation

Choose an application

Abstract

This publication presents evidence about the magnitude and severe consequences of comorbidity of mental and physical illnesses from a personal and societal perspective. Leading experts address the huge burden of co-morbidity to the affected individual as well as the public health aspects, the costs to society and interaction with factors stemming from the context of socioeconomic developments. The authors discuss the clinical challenge of managing cardiovascular illnesses, cancer, infectious diseases and other physical illness when they occur with a range of mental and behavioral disorders, including substance abuse, eating disorders and anxiety. Also covered are the organization of health services, the training of different categories of health personnel and the multidisciplinary engagement necessary to prevent and manage comorbidity effectively.

Anthocyanins

Authors: --- ---
ISBN: 9783038422280 9783038422297 Year: Pages: XVI, 376 DOI: 10.3390/books978-3-03842-229-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-10-31 16:55:34
License:

Loading...
Export citation

Choose an application

Abstract

This book contains 20 articles published in Molecules that concern the color quality of food and wine, anthocyanin biosynthesis and regulation, anthocyanin composition and the biological properties of anthocyanin pigments.

Advances in Polyhydroxyalkanoate (PHA) Production

Author:
ISBN: 9783038426370 9783038426363 Year: Pages: X, 245 DOI: 10.3390/books978-3-03842-636-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biotechnology
Added to DOAB on : 2017-12-22 11:01:59
License:

Loading...
Export citation

Choose an application

Abstract

Currently, we are witnessing highly dynamic research efforts related to the exciting field of novel biodegradable plastic-like materials. These activities originate from a growing public awareness of prevailing ecological problems associated to, e.g., rising piles of plastic waste, increasing greenhouse gas emissions, and ongoing depletion of such fossil resources usually used for the synthesis of “full carbon backbone” plastics. Polyhydroxyalkanoate (PHA) biopolyesters, a family of versatile plastic-like materials produced by living microbes, are a future-oriented alternative to traditional plastics. If accomplished in an optimized way, production and the entire lifecycle of PHA are embedded into nature´s closed carbon cycle, which is underlined by PHA´s main benefits of being “biobased”, “biosynthesized”, “biocompatible”, and “biodegradable”.Sustainable and economically feasible PHA synthesis, especially on an industrially relevant scale, requires all production steps to be understood and improved. Among other aspects, this calls for new powerful production strains to be screened; knowledge about the proteome and genome of PHA accumulating organisms to be consolidated; the kinetics of the bioprocesses to be thoroughly understood; abundantly available inexpensive raw materials to be tested; the monomer composition of PHA to be adapted; (bio)chemical engineering to be optimized; and novel PHA recovery strategies to be developed in order to reduce energy and chemical inventory.The present book provides a comprehensive compilation of articles addressing all these different aspects; the individual chapters were composed by globally recognized front running experts from special niches of PHA research. We are convinced that this book will be of major benefit to the growing scientific community active in biopolymer research.

Listing 1 - 10 of 67 << page
of 7
>>
Sort by
Narrow your search

Publisher

MDPI - Multidisciplinary Digital Publishing Institute (65)

Coimbra University Press (1)

Karger (1)


License

CC by-nc-nd (67)


Language

english (55)

eng (11)

portuguese (1)


Year
From To Submit

2020 (19)

2019 (38)

2018 (5)

2017 (2)

2016 (1)

2015 (1)