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Marine Glycosides

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ISBN: 9783038979029 9783038979036 Year: Pages: 264 DOI: 10.3390/books978-3-03897-903-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-05-09 17:16:14
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In recent years, there has been a steady increase in the publication of papers on the chemistry, biology, and potential clinical uses of marine glycosides. Indeed, more than half of the papers published in this field are less than a decade old. Glycosides have been isolated from species as diverse as algae, fungi, anthozoans, and echinoderms. Even fish of the genus Pardachirus produce glycosides, which they use as shark repellents.The major interest in these compounds as potential drugs stems from their broad spectrum of biological effects. They have been shown to have antimicrobial, antifungal, anti-inflammatory, immune modulatory, and anticancer effects. The anticancer effects of marine glycosides include cell cycle suppression, the induction of apoptosis, and the inhibition of migration, invasion, and metastasis, as well as antiangiogenesis. Marine glycosides influence membrane permeability and have been shown to influence membrane transport at the molecular level through effects on transport carriers and pumps, as well as effects on ligand-gated and voltage-gated channels. Various marine glycosides have been shown to activate sphingomyelinase and ceramide synthesis, to inhibit topoisomerase activity, receptor tyrosine kinase activity, and multidrug resistance protein activity, and to antagonize eicosanoid receptors.This Special Issue covers the entire scope of marine organism-derived glycosides that are of potential value as pharmaceutical agents or leads. These include, but are not limited to, tetracyclic triterpene glycosides, other triterpene glycosides, steroid glycosides, and glycosides of non-isoprenoid aglycones.

Engineering Fluid Dynamics 2018

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ISBN: 9783039281121 / 9783039281138 Year: Pages: 256 DOI: 10.3390/books978-3-03928-113-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Technology (General)
Added to DOAB on : 2020-01-30 16:39:46
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“Engineering Fluid Dynamics 2018”. The topic of engineering fluid dynamics includes both experimental as well as computational studies. Of special interest were submissions from the fields of mechanical, chemical, marine, safety, and energy engineering. We welcomed both original research articles as well as review articles. After one year, 28 papers were submitted and 14 were accepted for publication. The average processing time was 37.91 days. The authors had the following geographical distribution: China (9); Korea (3); Spain (1); and India (1). Papers covered a wide range of topics, including analysis of fans, turbines, fires in tunnels, vortex generators, deep sea mining, as well as pumps.

Keywords

axial fan --- rotating stall --- aerodynamic noise --- numerical simulation --- noise spectrum --- centrifugal pump --- radiation noise --- distribution characteristic --- acoustic energy --- experimental research --- thermosyphon --- volume of fluid --- multiphase flow --- evaporation and condensation --- centrifugal pump --- impeller --- blade wrap angle --- blade exit angle --- optimized design --- deep sea mining --- manganese nodules exploitation --- hydraulic collecting --- suction flow field --- dimensional analysis --- circumferential groove casing treatment --- sweep and lean --- CGCT-blade integrated optimization --- computational fluid dynamics (CFD) --- flow around cylinder --- fluid structure interaction (FSI) --- hydrodynamic response --- numerical methods --- simulation and modeling --- vortex induced vibration (VIV) ratio --- gas turbine --- axial gap --- hot streak --- heat transfer --- leading edge --- global optimization --- cavitation inception --- orthogonal test --- CFD simulation --- two-stage axial fan --- numerical simulation --- abnormal blade installation angle --- rotating stall --- Tesla turbine --- fluid dynamics --- disc thickness --- disc spacing distance --- isentropic efficiency --- plug-holing --- tunnel slope --- fire --- natural ventilation --- ventilation performance --- aspect ratio --- evacuation --- fire propagation --- tunnel vehicle fire --- unsteady heat release rate --- flow control --- vortex generators --- source term --- Computational Fluid Dynamics (CFD) --- OpenFOAM --- wind tunnel

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