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Insights and Advancements in Microfluidics

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ISBN: 9783038425168 9783038425175 Year: Pages: VI, 287 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering
Added to DOAB on : 2017-10-02 11:51:06
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Microfluidics has developed rapidly over the past three decades. Relentless diagnostic, medical and chemical applications have been demonstrated in various applications, plateforms and tools. Have microfluidics realized its full potential? Or is it only a leveraging academic tool? In this Special Issue, we focus on both insights and advancements in microfluidics. We invite emerging investigators and pioneers to contribute commentaries, perspectives and insightful reviews on related topics. The various insights from esteemed colleagues will be collated. We will also discuss technological breakthrough of original works in both short communications and full papers. The main idea is to stimulate the community and to provide an unique collection of insightful papers. We will also cover various topics ranging from 3D printing, paper-based microfludics to conventional polymer-based microfluidics which contributes to the technological advancements.

Organische Halbleiterbauelemente für mikrooptische Systeme

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ISBN: 9783866442047 Year: Pages: X, 199 p. DOI: 10.5445/KSP/1000007359 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:02:02
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Diese Arbeit befasst sich mit neuen Aspekten der Nutzung der Klasse der organischen Halbleiterbauelemente. Es wird dabei insbesondere die Integration organischer Bauelemente in mikrooptische Systeme untersucht. Dabei stehen sowohl das Design, die Herstellung und die Charakterisierung als auch die Anwendung dieser Bauelemente in der Datenübertragung und Sensorik im Vordergrund.

Photonic crystal slabs for low-cost biosensors

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ISBN: 9783866445598 Year: Pages: VI, 165 p. DOI: 10.5445/KSP/1000019644 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:57
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Biosensors are devices that utilize biological recognition elements to selectively detect and analyze specific biological and chemical analyte substances. In this work a technology platform for label-free optical biosensors based on surface-functionalized photonic crystal slabs is proposed. Using this technology platform, low-cost solutions for three biotechnical questions are presented.

Mehrlagige mikrofluidische Systeme aus Polymeren zur zweidimensionalen Kapillarelektrophorese

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ISBN: 9783866445185 Year: Pages: VIII, 137 p. DOI: 10.5445/KSP/1000018080 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:59
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Im Rahmen dieser Arbeit wurde ein mehrlagiges mikrofluidisches Lab-on-a-Chip-System auf Polymerbasis für den Einsatz in der Ionenanalytik, Lebensmittelanalytik und Bioanalytik entwickelt. Hierfür wurden Folienchips mit einer integrierten Membran auf PC-COC-Basis und Folienchips auf PEEK-Basis hergestellt, welche die Durchführung einer zweidimensionalen Kapillarelektrophorese (2D-CE) mit kapazitiv gekoppelter kontaktloser Leitfähigkeitsdetektion auf einem Chip ermöglichen.

Microdevices and Microsystems for Cell Manipulation

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ISBN: 9783038426189 9783038426191 Year: Pages: VII, 171 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Physics (General)
Added to DOAB on : 2017-12-28 13:52:56
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Microfabricated devices and systems capable of micromanipulation are well-suited for the manipulation of cells. These technologies are capable of a variety of functions, including cell trapping, cell sorting, cell culturing, and cell surgery, often at single-cell or sub-cellular resolution. These functionalities are achieved through a variety of mechanisms, including mechanical, electrical, magnetic, optical, and thermal forces. The operations that these microdevices and microsystems enable are relevant to many areas of biomedical research, including tissue engineering, cellular therapeutics, drug discovery, and diagnostics. This Special Issue will highlight recent advances in the field of cellular manipulation. Technologies capable of parallel single-cell manipulation are of special interest.

Microscale Surface Tension and Its Applications

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ISBN: 9783039215645 / 9783039215652 Year: Pages: 240 DOI: 10.3390/books978-3-03921-565-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 16:10:12
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Building on advances in miniaturization and soft matter, surface tension effects are a major key to the development of soft/fluidic microrobotics. Benefiting from scaling laws, surface tension and capillary effects can enable sensing, actuation, adhesion, confinement, compliance, and other structural and functional properties necessary in micro- and nanosystems. Various applications are under development: microfluidic and lab-on-chip devices, soft gripping and manipulation of particles, colloidal and interfacial assemblies, fluidic/droplet mechatronics. The capillary action is ubiquitous in drops, bubbles and menisci, opening a broad spectrum of technological solutions and scientific investigations. Identified grand challenges to the establishment of fluidic microrobotics include mastering the dynamics of capillary effects, controlling the hysteresis arising from wetting and evaporation, improving the dispensing and handling of tiny droplets, and developing a mechatronic approach for the control and programming of surface tension effects. In this Special Issue of Micromachines, we invite contributions covering all aspects of microscale engineering relying on surface tension. Particularly, we welcome contributions on fundamentals or applications related to:Drop-botics: fluidic or surface tension-based micro/nanorobotics: capillary manipulation, gripping, and actuation, sensing, folding, propulsion and bio-inspired solutions; Control of surface tension effects: surface tension gradients, active surfactants, thermocapillarity, electrowetting, elastocapillarity; Handling of droplets, bubbles and liquid bridges: dispensing, confinement, displacement, stretching, rupture, evaporation; Capillary forces: modelling, measurement, simulation; Interfacial engineering: smart liquids, surface treatments; Interfacial fluidic and capillary assembly of colloids and devices; Biological applications of surface tension, including lab-on-chip and organ-on-chip systems. We expect novel as well as review contributions on all aspects of surface tension-based micro/nanoengineering. In line with Micromachines' policy, we also invite research proposals that introduce ideas for new applications, devices, or technologies.

Keywords

mist capillary self-alignment --- laser die transfer --- hydrophilic/superhydrophobic patterned surfaces --- microasssembly --- droplet transport --- microfluidics --- vibrations --- contact line oscillation --- asymmetric surfaces --- anisotropic ratchet conveyor --- surface tension --- capillary --- bearing --- wetting --- computational fluid dynamics --- droplet manipulation --- lab-on-a-chip --- microfluidics --- non-invasive control --- photochemical reaction --- photoresponsible surfactant --- surface tension --- two-phase flow --- wettability --- electrowetting --- actuation --- capillary pressure --- lab-on-a-chip --- Nasturtium leaf --- smart superhydrophobic surface --- hot drop --- condensation --- microtexture melting --- self-lubricating slippery surface --- wettability gradient --- electrosurgical scalpels --- anti-sticking --- soft tissue --- continuous-flow reactor --- mixing --- solutal Marangoni effect --- relaxation oscillations --- super-hydrophobic --- durable --- adhesion --- corrosive resistance --- droplet --- vibrations --- transport --- microfluidics --- self-cleaning surface --- superhydrophobic --- superhydrophilic --- superomniphobic --- microfluidics --- electrodynamic screen --- gecko setae --- micropipette-technique --- air-water surface --- oil-water interface --- soluble surfactant --- insoluble lipids --- “black lipid films” --- “droplet-interface-bilayers” --- equilibrium --- dynamic --- adsorption --- gas-microbubbles --- oil-microdroplets --- lung-surfactants --- nanoprecipitation --- microfluidics --- capillary gripper --- pick and place --- micromanufacturing --- two-photon polymerization --- stereolithography --- polydimethylsiloxane (PDMS) replication --- rigid gas permeable contact lenses --- wettability --- hydrophilic --- hydrophobic --- 355 nm UV laser --- surface treatment --- microstructure --- contact angle --- droplets --- liquid bridge --- microfabrication --- micromanipulation --- pick-and-place --- soft robotics --- surface tension --- wetting

Experimental and Numerical Studies in Biomedical Engineering

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ISBN: 9783039212477 / 9783039212484 Year: Pages: 130 DOI: 10.3390/books978-3-03921-248-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 16:10:12
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The term ‘biomedical engineering’ refers to the application of the principles and problem-solving techniques of engineering to biology and medicine. Biomedical engineering is an interdisciplinary branch, as many of the problems health professionals are confronted with have traditionally been of interest to engineers because they involve processes that are fundamental to engineering practice. Biomedical engineers employ common engineering methods to comprehend, modify, or control biological systems, and to design and manufacture devices that can assist in the diagnosis and therapy of human diseases. This Special Issue of Fluids aims to be a forum for scientists and engineers from academia and industry to present and discuss recent developments in the field of biomedical engineering. It contains papers that tackle, both numerically (Computational Fluid Dynamics studies) and experimentally, biomedical engineering problems, with a diverse range of studies focusing on the fundamental understanding of fluid flows in biological systems, modelling studies on complex rheological phenomena and molecular dynamics, design and improvement of lab-on-a-chip devices, modelling of processes inside the human body as well as drug delivery applications. Contributions have focused on problems associated with subjects that include hemodynamical flows, arterial wall shear stress, targeted drug delivery, FSI/CFD and Multiphysics simulations, molecular dynamics modelling and physiology-based biokinetic models.

Glassy Materials Based Microdevices

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ISBN: 9783038976189 Year: Pages: 284 DOI: 10.3390/books978-3-03897-619-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Electrical and Nuclear Engineering --- General and Civil Engineering --- Technology (General)
Added to DOAB on : 2019-03-21 15:50:41
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Microtechnology has changed our world since the last century, when silicon microelectronics revolutionized sensor, control and communication areas, with applications extending from domotics to automotive, and from security to biomedicine. The present century, however, is also seeing an accelerating pace of innovation in glassy materials; as an example, glass-ceramics, which successfully combine the properties of an amorphous matrix with those of micro- or nano-crystals, offer a very high flexibility of design to chemists, physicists and engineers, who can conceive and implement advanced microdevices. In a very similar way, the synthesis of glassy polymers in a very wide range of chemical structures offers unprecedented potential of applications. The contemporary availability of microfabrication technologies, such as direct laser writing or 3D printing, which add to the most common processes (deposition, lithography and etching), facilitates the development of novel or advanced microdevices based on glassy materials. Biochemical and biomedical sensors, especially with the lab-on-a-chip target, are one of the most evident proofs of the success of this material platform. Other applications have also emerged in environment, food, and chemical industries. The present Special Issue of Micromachines aims at reviewing the current state-of-the-art and presenting perspectives of further development. Contributions related to the technologies, glassy materials, design and fabrication processes, characterization, and, eventually, applications are welcome.

Keywords

micro-crack propagation --- severing force --- quartz glass --- micro-grinding --- microfluidics --- single-cell analysis --- polymeric microfluidic flow cytometry --- single-cell protein quantification --- glass molding process --- groove --- roughness --- filling ratio --- label-free sensor --- optofluidic microbubble resonator --- detection of small molecules --- chalcogenide glass --- infrared optics --- precision glass molding --- aspherical lens --- freeform optics --- micro/nano patterning --- 2D colloidal crystal --- soft colloidal lithography --- strain microsensor --- vectorial strain gauge --- compound glass --- microsphere --- resonator --- lasing --- sensing --- microresonator --- whispering gallery mode --- long period grating --- fiber coupling --- distributed sensing --- chemical/biological sensing --- direct metal forming --- glassy carbon micromold --- enhanced boiling heat transfer --- metallic microstructure --- microspheres --- microdevices --- glass --- polymers --- solar energy --- nuclear fusion --- thermal insulation --- sol-gel --- Ag nanoaggregates --- Yb3+ ions --- down-shifting --- photonic microdevices --- alkali cells --- MEMS vapor cells --- optical cells --- atomic spectroscopy --- microtechnology --- microfabrication --- MEMS --- microfluidic devices --- laser materials processing --- ultrafast laser micromachining --- ultrafast laser welding --- enclosed microstructures --- glass --- porous media --- fluid displacement --- spray pyrolysis technique --- dielectric materials --- luminescent materials --- photovoltaics --- frequency conversion --- device simulations --- europium --- luminescence --- hybrid materials --- microdevices --- light --- photon --- communications --- waveguides --- fibers --- biosensors --- microstructured optical fibers --- whispering gallery modes --- light localization --- optofluidics --- lab-on-a-chip --- femtosecond laser --- laser micromachining --- diffusion

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