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Synaptic Plasticity

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ISBN: 9789535132332 9789535132349 Year: Pages: 222 DOI: 10.5772/63260 Language: English
Publisher: IntechOpen
Subject: Surgery
Added to DOAB on : 2019-10-03 07:51:50

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Abstract

Nerve cells form thousands of contact points, the synapses, to communicate information with other neurons and target cells. Synapses are sites for changes in brain function through modification of synaptic transmission termed synaptic plasticity. The study of synaptic plasticity has flourished over the years with the advancement of technical breakthroughs and is a timely scientific endeavor today just like it was several decades ago. This book contributes to our understanding of synaptic plasticity at the molecular, biochemical, and cellular systems and behavioral level and informs the reader about its clinical relevance. The book contains ten chapters in three sections: (1) ""Mechanisms of Synaptic Plasticity,"" (2) ""Neural Plasticity,"" and (3) ""Plasticity and Neurological Diseases."" The book provides detailed and current reviews in these different areas written by experts in their respective fields. The mechanisms of synaptic plasticity and its relation to neurological diseases are featured prominently as a recurring theme throughout most chapters. This book will be most useful for neuroscientists and other scientists alike and will contribute to the training of current and future students who find the plastic nervous system as fascinating as many generations before them.

Neuroplasticity - Insights of Neural Reorganization

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ISBN: 9781789231946 9781789231953 Year: Pages: 204 DOI: 10.5772/intechopen.68156 Language: English
Publisher: IntechOpen
Subject: Surgery
Added to DOAB on : 2019-10-03 07:51:51

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This book provides comprehensive and up-to-date insights into emerging research trends on neuroplasticity with current or future treatments for neurodevelopment and neurodegenerative diseases. The authors discuss structural and functional changes associated with cortical remapping, sensory substitution, synaptic and non-synaptic compensatory plasticity due to brain damage, brain training, chronic pain, meditation, music, exercise and related states. Key features include pathogenesis, and existing and new therapies together with a pharmacological and non-pharmacological approach in clinical treatment and management. The authors are established experts that contributed significantly to a better understanding of the etiology of neuroplasticity. This book is recommended to healthcare providers, clinical scientists, students and patients.

The Hippocampus - Plasticity and Functions

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ISBN: 9781789233568 9781789233575 Year: Pages: 178 DOI: 10.5772/intechopen.68877 Language: English
Publisher: IntechOpen
Subject: Surgery
Added to DOAB on : 2019-10-03 07:51:51

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The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.

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