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Morphological Plant Modeling: Unleashing Geometric and Topological Potential within the Plant Sciences

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889452972 Year: Pages: 296 DOI: 10.3389/978-2-88945-297-2 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Botany
Added to DOAB on : 2018-02-27 16:16:44
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An increasing population faces the growing demand for agricultural products and accurate global climate models that account for individual plant morphologies to predict favorable human habitat. Both demands are rooted in an improved understanding of the mechanistic origins of plant development. Such understanding requires geometric and topological descriptors to characterize the phenotype of plants and its link to genotypes. However, the current plant phenotyping framework relies on simple length and diameter measurements, which fail to capture the exquisite architecture of plants. The Research Topic “Morphological Plant Modeling: Unleashing Geometric and Topological Potential within the Plant Sciences” is the result of a workshop held at National Institute for Mathematical and Biological Synthesis (NIMBioS) in Knoxville, Tennessee. From 2.-4. September 2015 over 40 scientists from mathematics, computer science, engineering, physics and biology came together to set new frontiers in combining plant phenotyping with recent results from shape theory at the interface of geometry and topology. In doing so, the Research Topic synthesizes the views from multiple disciplines to reveal the potential of new mathematical concepts to analyze and quantify the relationship between morphological plant features. As such, the Research Topic bundles examples of new mathematical techniques including persistent homology, graph-theory, and shape statistics to tackle questions in crop breeding, developmental biology, and vegetation modeling. The challenge to model plant morphology under field conditions is a central theme of the included papers to address the problems of climate change and food security, that require the integration of plant biology and mathematics from geometry and topology research applied to imaging and simulation techniques. The introductory white paper written by the workshop participants identifies future directions in research, education and policy making to integrate biological and mathematical approaches and to strengthen research at the interface of both disciplines.

Quantitative analysis of neuroanatomy

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197965 Year: Pages: 244 DOI: 10.3389/978-2-88919-796-5 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.

Morphologically complex words in the mind/brain

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198030 Year: Pages: 230 DOI: 10.3389/978-2-88919-803-0 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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The question of how morphologically complex words (assign-ment, listen-ed) are represented and processed in the brain has been one of the most hotly debated topics in the cognitive neuroscience of language. Do complex words engage cortical representations and processes equivalent to single lexical objects or are they processed as sequences of separate morpheme-like units? Research on morphological processing has suggested that adults make efficient use of both lexical (i.e., whole word) storage and retrieval, as well as combinatorial computation in processing morphologically complex words. Psycholinguistic studies have demonstrated that processing of complex words can be affected both by properties of the morphemes and the whole words, such as their frequency, transparency, and regularity. Furthermore, this research has been informative about the time-course of complex word recognition and production, and the role of morphological structure in these processes. At the neural level, left-hemisphere inferior frontal and superior temporal areas, and negative-going event-related potentials, have been consistently associated with morphological processing. While most previous research has been done on the recognition of morphologically complex words in adult native speakers, much less is known about neurocognitive processes involved in the on-line production of morphologically complex words, and even less on morphological processing in children and non-native speakers. Moreover, we have limited understanding of how linguistically distinct morphological processes, e.g. inflectional (listen-ed) versus derivational (assign-ment), are handled by the cortical language networks. This e-book gives an up-to-date overview of the questions currently addressed in the field of morphological processing. It highlights the significance of morphological information in language processing, both written and spoken, as assessed by a variety of methods and approaches. It also points to a number of unresolved issues, and provides future directions for research in this key area of cognitive neuroscience of language.

Keywords

morphology --- derivation --- inflection --- Compound --- L2 --- Dyslexia --- ERP --- MEG --- semantics --- decomposition

The Grammar of Multilingualism

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889450121 Year: Pages: 195 DOI: 10.3389/978-2-88945-012-1 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Psychology
Added to DOAB on : 2018-02-27 16:16:44
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This volume investigates the nature of grammatical representations in speakers who master multiple languages. Since the early days of modern formal approaches to grammar, most work has been based on the language of monolingual humans. Less work has been conducted based on data from speakers who possess more than one language. Although important insights have been gained from a monolingual focus, there is every reason to believe that bi- and multilingual data can inform linguistic theory. A lot of ongoing work demonstrates that this is indeed the case, and the current volume contributes to this growing literature. Thus, the research topic addresses a number of questions relating to grammatical structures in multilingual speakers as well as the methodological issues that arise in the context of studying such speakers. A better understanding of the grammatical sides of multilingualism is crucial for understanding the human language capacity and in turn for offering better advice to the public concerning issues of language choice for multilingual children and adults, education, and language deficits in multilingual individuals.

Neuroanatomy and transgenic technologies

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195138 Year: Pages: 139 DOI: 10.3389/978-2-88919-513-8 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2015-12-03 13:02:24
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Neuroanatomists increasingly rely on techniques enabling them to manipulate genes in defined brain cell populations. In particular, engineered transgenes, which encode a variety of fluorescent reporter proteins can be inserted into the genome or delivered into desired brain regions using viral vectors, thereby allowing the labeling of molecularly-defined populations of neurons and/or glial cells. Transgenic technology can also be used to selectively delete genes in targeted neuronal populations or bi-directionally modulate their electrical excitability using optogenetic or chemogenetic techniques. One of the primary advantages of using transgenic reagents is to simplify the identification and tracing of targeted population of brain cells, which can be laborious using traditional techniques in neuroanatomy. In this research topic, we assembled up-to-date reviews and original articles that demonstrate the versatility and power of transgenic tools in advancing our knowledge of the nervous system, with a special emphasis on the application of transgenic technology to neuroanatomical questions.

Neuronal Mechanics and Transport

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198238 Year: Pages: 212 DOI: 10.3389/978-2-88919-823-8 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-01-19 14:05:46
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Understanding the underlying mechanisms of how axons and dendrites develop is a fundamental problem in neuroscience and a main goal of research on nervous system development and regeneration. Previous studies have provided a tremendous amount of information on signaling and cytoskeletal proteins regulating axonal and dendritic growth and guidance. However, relatively little is known about the relative contribution and role of cytoskeletal dynamics, transport of organelles and cytoskeletal components, and force generation to axonal elongation. Advancing the knowledge of these biomechanical processes is critical to better understand the development of the nervous system, the pathological progression of neurodegenerative diseases, acute traumatic injury, and for designing novel approaches to promote neuronal regeneration following disease, stroke, or trauma. Mechanical properties and forces shape the development of the nervous system from the cellular up to the organ level. Recent advances in quantitative live cell imaging, biophysical, and nanotechnological methods such as traction force microscopy, optical tweezers, and atomic force microscopy have enabled researchers to gain better insights into how cytoskeletal dynamics and motor-driven transport, membrane-dynamics, adhesion, and substrate rigidity influence axonal elongation. Given the complexity and mechanical nature of this problem, mathematical modeling contributes significantly to our understanding of neuronal mechanics. Nonetheless, there has been limited direct interaction and discussions between experimentalists and theoreticians in this research area. The purpose of this Frontiers Research Topic is to highlight exciting and important work that is currently developing in the fields of neuronal cell biology, neuronal mechanics, intracellular transport, and mathematical modeling in the form of primary research articles, reviews, perspectives, and commentaries.

Wiring Principles of Cerebral Cortex

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889196920 Year: Pages: 171 DOI: 10.3389/978-2-88919-692-0 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2016-08-16 10:34:25
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Cerebral cortex is probably the most complex biological network. Here many millions of individual neurons, the functional units of cortex, are interconnected through a massive yet highly organized pattern of axonal and dendritic wiring. This wiring enables both near and distant cells to coordinate their responses and generate a rich variety of cognitions and behaviours. When the wiring is damaged through disease or trauma it may reorganize but this may lead to characteristic pathological behaviours. While there have been significant advances in mapping cortical connectivity, the organizing principles and function of this connectivity are not well understood. On the one hand, there appears to be general design constraints governing cortical wiring, as first recognised by Rámon y Cajal's in his laws of conduction, material, and volume conservation. Yet on the other hand, particular patterns of cortical wiring exist to serve specific functions. There is a wide gap in understanding how the response and connectivity properties of a single neuron contribute to emergent network functions such as in detecting perceptually relevant features. Unravelling this intimate causal relationship represents one of the major challenges in neuroscience. This Research Topic will examine progress in understanding cortical wiring principles. This Research Topic aims to draw together recent advances in methods and understanding as well as recent challenges to existing ideas about how cerebral cortex is wired. This is particularly timely because new automated techniques may soon yield huge datasets in need of explanation. Recent studies have, for instance, empirically evaluated Rámon y Cajal's conservation laws for cerebral cortex, while others have shown some unexpected connectivity features that may refine the traditional view of how corticocortical connections are organised with regard to functional representations of auditory, somatosensory and visual cortices. Understanding these data will help improve the fidelity of neural models of cerebral cortical function and take into account the diversity of connections at both micro- and mesoscopic scales not seen at such a depth before.

Perceptual Linguistic Salience: Modeling Causes and Consequences

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451777 Year: Pages: 134 DOI: 10.3389/978-2-88945-177-7 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2017-08-28 14:01:09
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Recent years have seen an upsurge of interest in the notion of salience in linguistics and related disciplines. While in top-down salience, perceivers endogenously direct their attention to a certain stimulus, in the bottom-up salience, it is the stimulus itself which attracts attention. In prototypical cases of bottom-up salience, the stimulus stands out because it is incongruous with a given ground by virtue of intrinsic physical characteristics. But a stimulus may also cause surprise by virtue of deviating from a cognitive ground, e.g., when violating social or probabilistic expectations. This has prompted researchers to examine the relationship between expectations and the perceptual salience of linguistic stimuli in new ways. This e-book features contributions from different scientific frameworks. The reader will find commentaries, reviews, and original research articles on models of sociolinguistic and morphological salience, the role of attention, affect, and predictability, and on how salient items are processed, categorized and learned. Taken together, the articles in this volume contribute to our understanding of how the perceptual salience of linguistic forms and variants can be theoretically framed and methodologically operationalized in different areas of linguistic processing.

Sea Level Variability and Change

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451500 Year: Pages: 174 DOI: 10.3389/978-2-88945-150-0 Language: English
Publisher: Frontiers Media SA
Subject: Oceanography --- Science (General)
Added to DOAB on : 2017-08-28 14:01:09
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In June 2015 we held a workshop on the beautiful island of Mallorca, Spain with a focus on sea level variability and change. Over 120 sea level experts from around the world attended this workshop, from a range of different disciplines. The main aims of the workshop were to: 1.) Evaluate the current state-of-knowledge of sea level science; 2.) Identify gaps and unresolved questions in any aspect of sea level science; and 3.) Design future research to address these issue. All aspects of sea level changes were covered, from global to regional, observations and modelling, processes driving mean sea level changes and extremes, from the geological scale to the instrumental era and future projections and including impacts on the coastal zones. This E-Book presents papers that came out of that workshop. Overall, these papers illustrate the multi-disciplinary nature of sea level research, cross-cutting many fields of research including: oceanography, meteorology, geology, coastal morphodynamics, engineering and the social-economic aspects. Collectively, theses articles represent an interesting range of perspectives and original studies that contribute to understanding the dynamic nature of sea level and its impacts across a wide range of time and space scales. Enjoy reading them!

A Broader View for Plant EvoDevo: Novel Approaches for Diverse Model Systems

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451531 Year: Pages: 184 DOI: 10.3389/978-2-88945-153-1 Language: English
Publisher: Frontiers Media SA
Subject: Botany --- Science (General)
Added to DOAB on : 2017-08-28 14:01:09
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This collection attempts to integrate work pertaining to a fundamental question in plant evolution: What are the molecular underpinnings for the origin of different plant forms? Among the many facets this question touches are the transition to land, the emergence of vascular plants, the origin of the seed and the origin and diversification of floral form. We aim to bring to the forefront the most salient and original plant systems and approaches within an inclusive phylogenetic context that encompasses representatives of the major lineages of land plants.

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