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Progress in Physical activity and Exercise and Affective and Anxiety Disorders: Translational Studies, Perspectives and Future Directions

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889194711 Year: Pages: 78 DOI: 10.3389/978-2-88919-471-1 Language: English
Publisher: Frontiers Media SA
Subject: Psychiatry --- Medicine (General)
Added to DOAB on : 2016-03-10 08:14:33
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Physical activity and exercise were receiving a great attention as a strategy of prevention and treatment of affective and some anxiety disorders. Many studies have showed the efficacy of exercise in major depression and at depressed episode of bipolar patients, as well as, some authors shows the benefits of exercise in some anxiety disorders like Generalized Anxiety Disorder and Panic. Despite their efficacy, little is known concerning the main mechanisms related to the antidepressant and anxiolytic effects of exercise. Several studies in an animal model using Neurotrophic Factors, Oxidative Stress, Immunologic response and other biological markers reveal promising results. However, few studies were conducted in clinical samples. Additional to the antidepressant and anxiolytic effects, exercise appears improve QoL in major depressed, bipolar and anxiety patients. Theoretically, this increase may be associated with cognitive improvements, improvements at sleep quality, physical functioning, as well as other psychological issues as self-esteem, self-concept, and general well-being. The propose of this topic is to address the novelty and most recent research, related to antidepressant and anxiolytic effects of physical activity and exercise in patients with affective and anxiety disorders, as well as the issues associated with QoL improvement.The topic is looking for: – Clinical trials using exercise and physical activity as a treatment affective and anxiety disorders. – Studies investigating the optimal prescription factors (dose, volume, intensity, setting, frequency) associated with antidepressant and anxiolytic effects of physical activity and exercise for affective and anxiety disorder patients. – Original studies, comprehensive reviews, hypothesis and opinions concerning the mechanisms of antidepressant and anxiolytic effects of physical activity and exercise in affective and anxiety disorder patients. – Original studies, comprehensive reviews, hypothesis and opinions concerning other benefits of physical activity and exercise like : cognition, weight gain prevention and QoL in affective and anxiety disorder patients. – Translational research. – Studies of cost-efficacy analysis

Psychological Issues in Amyotrophic Lateral Sclerosis

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197583 Year: Pages: 103 DOI: 10.3389/978-2-88919-758-3 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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Amyotrophic lateral sclerosis is a fatal and progressive disease, characterized by progressive muscles weakness, with consequent loss of physical capacities. Patients become relentlessly immobile and, in the late stages of the disease, develop a "locked-in" state in which only residual muscular movement is possible, but the intellect and the personality usually remain unimpaired. At now, there is no cure for ALS. The psychological impact of the disease is huge, on both patients and caregivers. Aim of the present Research Topic is to collect new evidence about quality of life, depression, anxiety, pain, spiritual and existential issues, hope and hopelessness in the ALS field, with attention to both patients and their caregivers. Emphasis will be provided to the investigation of psychological support and the possible role of psychologists in this challenging field. Keywords: Amyotrophic Lateral Sclerosis; Health Psychology; Clinical Psychology, Motor Neuron Disorder; Quality of Life. Subtopics:The subtopics to be covered in the Research Topic include, but not limited to:1. Assessment of psychological variables in ALS2. Quality of life during the course of the illness3. Impact of technological assistance to illness (wheelchairs, NIV...)4. Interfaces among biological, psychosocial, and social factors5. Psychological and psychotherapeutic interventions6. Couple and family relationships7. Research methodology, measurement and statistics8. Cultural and social features of ALS9. Professional issues, including training and supervision10. Implications of research findings for health-related policy

Psychosocial Advances in Neuro-Oncology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197828 Year: Pages: 142 DOI: 10.3389/978-2-88919-782-8 Language: English
Publisher: Frontiers Media SA
Subject: Oncology --- Medicine (General)
Added to DOAB on : 2016-04-07 11:22:02
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Neuro-oncology is a rapidly growing field concerned with scientific developments and clinical applications related to neuroscience, neuropsychology, cancer and oncology. Neuro-oncological disorders include cancers that directly affect the central nervous system (CNS), such as brain tumours and brain metastases, and non-CNS cancers with treatments that produce neurocognitive impairment. To date, the biological mechanisms and neuropsychological effects of brain tumour and cancer have been the dominant focus in neuro-oncology literature. In terms of psychosocial aspects of care, people’s understanding of their diagnosis and symptoms and how they cope with their illness has a major influence on their emotional well-being and quality of life.The development and evaluation of psychological and supportive care interventions for people with brain tumour is an area of emerging research and of high interest to health professionals working in the field. This Research Topic aims to enhance understanding of the psychological and social consequences of brain tumour and other cancers impacting neurocognitive function. It also aims to showcase new developments in assessment and psychosocial intervention approaches.

Neuro-Development and Psychological Issues in Congenital Heart Defects

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889454280 Year: Pages: 87 DOI: 10.3389/978-2-88945-428-0 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Pediatrics
Added to DOAB on : 2018-11-16 17:17:57
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The advances in the peri-operative management of congenital heart defects have substantially improved the survival of infants over the last few decades, reaching >95% survival in the reports of the international congenital data-base from the European Association of Cardio-Thoracic Surgery and form the Society of Thoracic Surgery (North-America).Nevertheless, the surviving children often experience neurodevelopmental deficits and behavioral, emotional and social issues. These problems often have a profound impact on the quality of life of the growing population of these children at risk and their families.

Neurological and psychiatric disorders in endocrine diseases

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195893 Year: Pages: 97 DOI: 10.3389/978-2-88919-589-3 Language: English
Publisher: Frontiers Media SA
Subject: Internal medicine --- Medicine (General) --- Neurology --- Science (General)
Added to DOAB on : 2016-03-10 08:14:32
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Neurological and psychiatric disorders can occur in endocrine diseases either in the setting of the clinical manifestations of the same (i.e., hyper- or hyposecretion of hormones or peptides from the endocrine glands) or as events secondary to the pathogenetic mechanisms of the endocrinopathy (i.e., autommunity affecting endocrine glands and the brain). Also the medical or surgical treatment of the endocrine disease can sometimes determine the occurrence of neurological or psychiatric abnormalities. Moreover some genetic alterations can lead to syndromes affecting both the endocrine and the nervous system with a variety of possible manifestations. In the last couple of decades a number of associations between dysfunctions of the endocrine system and neurological or psychiatric manifestations have appeared and only in the minority of the cases this link has been fully elucidated. Often the neurological or psychiatric alterations still represent a relevant challenge for clinicians with regard to the management of the patients. The complexity of the topic and the limited availability of laboratory research models for the study of the endocrine system-nervous system cross-interaction are making the scientific progresses intricate and, sometimes, slow. A dedicated focus to such broad and often still obscure topic might help and clarify the current state-of-the-art in the field and direct the goals of future research.

The Treatment of Metastatic Non-small Cell Lung Cancer (NSCLC) in New Era of Personalised Medicine

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195435 Year: Pages: 140 DOI: 10.3389/978-2-88919-543-5 Language: English
Publisher: Frontiers Media SA
Subject: Oncology --- Medicine (General)
Added to DOAB on : 2016-01-19 14:05:46
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Lung cancer is the leading cause of cancer related mortality in Canada and USA. Majority of the patients present in advanced stage of the disease and of these only about 2% will be alive at 5 years. NSCLC is the most common form of lung cancer, accounting for approximately 87% of cases. Systemic chemotherapies have been used to treat metastatic NSCLC for decades, but the improvements of outcomes have reached a plateau. Recent advances in understanding signalling pathways for malignant cells, their interconections,the importance of various receptors and biomarkers and the interplay between various oncogenes have led to the development of targeted treatments that are improving both efficacy and safety of the treatments. Knowledge about the advantages of treatments with the targeted agents in metastatic NSCLC is growing rapidly. Combining various targeted agents or sequencing them properly will be important in the era of personalised medicine and overcoming development of the resistence to various targeted agents will be challenging. The importance of a team work,from the diagnosis through various treatments, to supportive care, from the interventional radiologists, pneumologists or surgeons, who have to obtain a satisfactory tumor tissue specimen, to pathologists, radiation and medical oncologists, to supportive care specialists, will be described in our publications. We will cover completely present and future approaches to personalised medicine in this rapidly evolving field of metastatic NSCLC.

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