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Metabolomics

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ISBN: 9789535100461 Year: Pages: 376 DOI: 10.5772/1237 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:48

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Metabolomics is a rapidly emerging field in life sciences, which aims to identify and quantify metabolites in a biological system. Analytical chemistry is combined with sophisticated informatics and statistics tools to determine and understand metabolic changes upon genetic or environmental perturbations. Together with other 'omics analyses, such as genomics and proteomics, metabolomics plays an important role in functional genomics and systems biology studies in any biological science. This book will provide the reader with summaries of the state-of-the-art of technologies and methodologies, especially in the data analysis and interpretation approaches, as well as give insights into exciting applications of metabolomics in human health studies, safety assessments, and plant and microbial research.

Molecular Regulation of Endocytosis

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ISBN: 9789535106623 9789535142911 Year: Pages: 468 DOI: 10.5772/2989 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:49

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Molecular Regulation of Endocytosis is a compilation of scientific ""short stories"" about the entry of external substances into cells. As one can see from the chapters, endocytosis regulates diverse processes such as homeostasis of the cell, signal transduction, entry of pathogens and viruses. In addition to the experimental techniques embedded in each chapter, entire chapters are dedicated to experimental approaches that will be useful to all scientists and their model systems. For those more clinically oriented, the final chapters look to the future and ways of utilizing endocytic pathways for therapeutic purposes.

Cell Death - Autophagy, Apoptosis and Necrosis

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ISBN: 9789535122364 9789535142119 Year: Pages: 446 DOI: 10.5772/59648 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:49

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This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.

Autophagy in Current Trends in Cellular Physiology and Pathology

Authors: ---
ISBN: 9789535127260 9789535127277 9789535141525 Year: Pages: 526 DOI: 10.5772/61911 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:49

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Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.

Cryopreservation in Eukaryotes

Authors: ---
ISBN: 9789535127796 9789535127802 9789535141433 Year: Pages: 228 DOI: 10.5772/62605 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:49

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Since accidentally discovering the ability of glycerol on protecting cells from freezing damage, many researchers have been pursuing to develop cryopreservation methods of a very wide range of cells and some tissues, and these have found widespread applications in biology and medicine. From the point of view of living organisms, cryopreservation is a useful tool for ex situ conservation of genetic resources together with its contribution on conservation of their biodiversity. Cryopreservation in Eukaryotes includes totally 12 chapters, which have been written by the expert researchers in the field. The chapters are a comprehensive collection of the most frequently used methods for eukaryotes. With this book, every researcher will better understand the principles, background, and current status of cryopreservation in particular organisms.

Metabolomics - Fundamentals and Applications

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ISBN: 9789535128533 9789535128540 Year: Pages: 216 DOI: 10.5772/62614 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:49

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Metabolomics: Fundamentals and Applications authoritatively presents the basic principles and applications of metabolomics. Topics covered in this book range from the analysis of metabolites from different biological sources and their data processing and statistical analysis. This book serves as a basic guide for a wide range of audiences from less familiar with metabolomics techniques to more experienced researchers seeking to understand complex biological systems from the systems biology approach.

New Insights into Cell Culture Technology

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ISBN: 9789535131335 9789535131342 Year: Pages: 202 DOI: 10.5772/62590 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:50

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The book ""New Insights into Cell Culture Technology"" focuses on many advanced methods and techniques concerned with cell culture. The contributing authors have discussed various developments in cell culture methods, the application of insect cells for the efficient production of heterologous proteins, the expansion of human mesenchymal stromal cells for different clinical applications, the remote sensing of cell culture experiments and concepts for the development of cell culture bioprocess, continuous production of retroviral pseudotype vectors, and the production of oncolytic measles virus vectors for cancer therapy. This book is an original contribution of experts from different parts of the globe, and the in-depth information will be a significant resource for students, scientists, and physicians who are directly dealing with cells.

[""Culture"" is essential for human life and also the life of a cell. - Sivakumar Gowder]

Cytoskeleton - Structure, Dynamics, Function and Disease

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ISBN: 9789535131694 9789535131700 Year: Pages: 342 DOI: 10.5772/62622 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:50

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The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with ""motility"" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

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