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Neuroblastoma - Current State and Recent Updates

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ISBN: 9789535135838 9789535135845 Year: Pages: 168 DOI: 10.5772/66615 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:50

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Abstract

Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma.

Brain Tumors - An Update

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ISBN: 9781789235562 9781789235579 Year: Pages: 248 DOI: 10.5772/intechopen.70986 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:51

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We all know that the field of neuro-oncology is heterogeneous and under continuous development with the addition of new knowledge and information on a regular basis. The present book ""Brain Tumor - An Update"" is an attempt to share the personal experiences of experts who are involved in neuro-oncology-related research. Through this book, the authors share their experiences and provide details about the pathophysiology, neuroimaging approaches, and management options, and how to go about decision-making in patients with brain tumors. We hope that the valuable contributions from the authors shall facilitate understanding about brain tumors. I am grateful to all the authors who have contributed their tremendous expertise, and I would like to acknowledge the outstanding support of Ms. Danijela Sakic, Author Service Manager, IntechOpen Science, who collaborated tirelessly in crafting this book.

Glioma - Contemporary Diagnostic and Therapeutic Approaches

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ISBN: 9781789849530 9781789849547 Year: Pages: 258 DOI: 10.5772/intechopen.72102 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:52

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The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope was placed on the extension of tumor resection and popular supratotal resection. Significant progress has been made generally in glioma treatment with the use of modern radiotherapy and new chemotherapeutics. What do we want to see for the future? By way of stem cells, a specific medicine will be produced, individualized for the particular patient, and by using a microcapsule it will be implanted into the brain zone affected by the tumor by way of robot surgery and injection needle. This is not at all an unrealistic expectation in the next decade or two.

Primary Intracranial Tumors

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ISBN: 9781789854053 9781789854060 Year: Pages: 140 DOI: 10.5772/intechopen.75418 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:52

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This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone.

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