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Behcet's Disease

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ISBN: 9789535132257 9789535132264 Year: Pages: 220 DOI: 10.5772/65884 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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Abstract

Behcet's disease is a multisystem inflammatory disease with unknown etiology and has a unique geographic distribution. It is characterized by recurrent oral aphthous lesions, recurrent uveitis, skin lesions, and genital ulcerations. However, it may involve the eye, joints, and cardiovascular, gastrointestinal, and neurological systems at varying degrees as well as the skin and mucous membranes. The disease may manifest itself in a wide spectrum of symptoms ranging from mild symptoms to life-threatening symptoms or severe symptoms that may create permanent sequelae. Knowing the nature of the disease will make it easier to diagnose and manage the disease. This book was written by expert authors, and detailed epidemiology, etiopathogenesis, mucocutaneous findings, and systemic involvement of Behcet's disease are presented to readers.

Neutrophils

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ISBN: 9781789852851 9781789852868 Year: Pages: 98 DOI: 10.5772/intechopen.73927 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:52

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This book highlights the numerous important properties of neutrophils and their role in various diseases, and as a possible therapeutic target as well. The first chapter briefly discusses the main effector neutrophil functions, which is followed by two chapters discussing the importance of different neutrophil receptors (cannabinoid and Fc?R) and their role in various disease conditions. The fourth chapter discusses the differential expression profile of CD16+CD11b+ on the surface of neutrophils as a tool for the diagnosis of acute infections. The last chapter discusses the physics of the NADPH oxidase system and the use of different chemiluminigenic probes for the detection of various reactive oxygen intermediates of the circulating neutrophils.

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