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Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday

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ISBN: 9783038974161 9783038974178 Year: Pages: 256 DOI: 10.3390/books978-3-03897-417-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Biochemistry
Added to DOAB on : 2019-06-26 08:44:06
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Abstract

Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.

Keywords

Zingiber officinale --- gingerols --- cytotoxic activity --- oleanolic acid --- high-fat high-carbohydrate diet --- pre-diabetes --- glucose homeostasis --- insulin resistance --- atherosclerosis --- ROS --- HUVECs --- LOX-1 --- alkaloid --- granatane --- N-methylcadaverine --- N-methylpiperidine. reductive deamination --- Mucorales --- Rhizopus arrhizus --- sterol pattern --- antifungal effectivity --- gas chromatography-mass spectrometry (GC-MS) --- posaconazole --- sterol biosynthesis --- sterol 14?-demethylase --- sterol C24-methyltransferase --- mechanism-based inactivators --- antifungals --- azoles --- antiparasitic drugs --- human African trypanosomiasis --- Chagas disease --- synthesis --- squalene cyclase --- cycloartenol synthase --- triterpene --- fern --- Polystichum --- terpene --- isoprenoid --- divalent metal co-factor ligation --- antioxidant --- cholesterol --- degeneration --- oxysterol --- retina --- Smith-Lemli-Opitz syndrome --- algal sterols --- ergosterol biosynthesis --- infectious disease --- lipidomics --- oxyphytosterol --- pharmacognosy --- phytosterol --- sterolomics --- lupeol --- keratinocytes --- fibroblasts --- wound healing --- cell migration --- UV-radiation --- ZnO --- toxicity --- sterol content --- cholesterol --- leishmania --- solanaceae --- withanolides --- aurelianolides --- phytosterols --- mesocarp --- oilseed --- maturity --- pod-blast --- ?-tocopherol --- oil bodies --- campesterol --- stigmasterol --- ?-sitosterol --- sterol --- C4-demethylation complex (C4DMC) --- 4-methylsterol --- hormone --- steroid --- development --- genetic disease --- bile alcohol --- cholestanoic acid --- oxysterol --- sterolomics --- enzyme-assisted derivatization --- electrospray ionization-mass spectrometry --- Girard reagent --- n/a

Children on the Move: The Health of Refugee, Immigrant and Displaced Children

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ISBN: 9783039282005 9783039282012 Year: Pages: 142 DOI: 10.3390/books978-3-03928-201-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: History --- Migration --- Sociology --- Social Sciences
Added to DOAB on : 2020-04-07 23:07:09
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This Special Issue of Children will focus on the migration arc of children from their country of origin through the experience in refugee camps and, finally, to their arrival in in a new home. It will examine the impact experiencing migration as refugees, immigrants or those internally displaced due to war and conflict has on children’s health. Explored topics include adverse health conditions, trauma and mental health, best practice and care coordination. It explores specific populations, such as children with disabilities, unaccompanied minors and child separation at international borders. This Special Issue also includes an examination of new clinical guidelines, the development of new care systems and advocacy for new policies. It also provides a summary of the UN Convention on the Rights of the Child’s specific mandate to provide for the most vulnerable children in need.

Flood Forecasting Using Machine Learning Methods

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ISBN: 9783038975489 Year: Pages: 376 DOI: 10.3390/books978-3-03897-549-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Environmental Engineering
Added to DOAB on : 2019-03-08 11:42:05
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This book is a printed edition of the Special Issue Flood Forecasting Using Machine Learning Methods that was published in Water

Keywords

data scarce basins --- runoff series --- data forward prediction --- ensemble empirical mode decomposition (EEMD) --- stopping criteria --- method of tracking energy differences (MTED) --- deep learning --- convolutional neural networks --- superpixel --- urban water bodies --- high-resolution remote-sensing images --- monthly streamflow forecasting --- artificial neural network --- ensemble technique --- phase space reconstruction --- empirical wavelet transform --- hybrid neural network --- flood forecasting --- self-organizing map --- bat algorithm --- particle swarm optimization --- flood routing --- Muskingum model --- machine learning methods --- St. Venant equations --- rating curve method --- nonlinear Muskingum model --- hydrograph predictions --- flood routing --- Muskingum model --- hydrologic models --- improved bat algorithm --- Wilson flood --- Karahan flood --- flood susceptibility modeling --- ANFIS --- cultural algorithm --- bees algorithm --- invasive weed optimization --- Haraz watershed --- ANN-based models --- flood inundation map --- self-organizing map (SOM) --- recurrent nonlinear autoregressive with exogenous inputs (RNARX) --- ensemble technique --- artificial neural networks --- uncertainty --- streamflow predictions --- sensitivity --- flood forecasting --- extreme learning machine (ELM) --- backtracking search optimization algorithm (BSA) --- the upper Yangtze River --- deep learning --- LSTM network --- water level forecast --- the Three Gorges Dam --- Dongting Lake --- Muskingum model --- wolf pack algorithm --- parameters --- optimization --- flood routing --- flash-flood --- precipitation-runoff --- forecasting --- lag analysis --- random forest --- machine learning --- flood prediction --- flood forecasting --- hydrologic model --- rainfall–runoff, hybrid & --- ensemble machine learning --- artificial neural network --- support vector machine --- natural hazards & --- disasters --- adaptive neuro-fuzzy inference system (ANFIS) --- decision tree --- survey --- classification and regression trees (CART), data science --- big data --- artificial intelligence --- soft computing --- extreme event management --- time series prediction --- LSTM --- rainfall-runoff --- flood events --- flood forecasting --- data assimilation --- particle filter algorithm --- micro-model --- Lower Yellow River --- ANN --- hydrometeorology --- flood forecasting --- real-time --- postprocessing --- machine learning --- early flood warning systems --- hydroinformatics --- database --- flood forecast --- Google Maps

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2020 (1)

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