Search results: Found 45

Listing 1 - 10 of 45 << page
of 5
>>
Sort by
Pharmacokinetics and Drug Metabolism in Canada: The Current Landscape

Authors: ---
ISBN: 9783038427971 9783038427988 Year: Pages: VIII, 302 DOI: 10.3390/books978-3-03842-798-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2018-04-06 13:44:18
License:

Loading...
Export citation

Choose an application

Abstract

Canadian Pharmaceutical Scientists have a rich history of ground-breaking research in pharmacokinetics and drug metabolism undertaken throughout its Pharmacy and Medical Schools and within the Pharmaceutical and biotechnology industry. The principle of drug Absorption, Distribution, Metabolism and Excretion (ADME) is the foundational basis of rationale drug-design, and pharmacotherapy. The study of ADME and its descriptive quantitative analysis is the basis of pharmacokinetics. Pharmacokinetics is fundamental in the development of a new chemical entity into a marketable product and is essential in understanding the bioavailability, bioequivalence and biosimilarities of drugs. Pharmacokinetics and drug development studies facilitate an understanding of organ-based functionality. Population pharmacokinetic variability and the modeling of drug concentrations has significant utility in translating individual response in a target patient population.This special issue serves to highlight and capture the contemporary progress and current landscape of pharmacokinetics and drug metabolism within the prevailing Canadian context. We invite articles on all aspects of Pharmacokinetics and Drug Metabolism studies highlighting the world-class research currently undertaken in Canada for this special issue.

Nanocolloids for Nanomedicine and Drug Delivery

Author:
ISBN: 9783038974277 9783038974284 Year: Pages: 272 DOI: 10.3390/books978-3-03897-428-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General) --- Physics (General)
Added to DOAB on : 2019-01-17 11:56:21
License:

Loading...
Export citation

Choose an application

Abstract

This Special Issue highlights novel nanocolloids like magnetic nanoparticles, nanomicelles, nanoliposomes, nanocapsules, and nanoclays, stimulating novel interests and ideas in research groups involved in the development of novel nanotools within the different areas of nanomaterials. The publication of original articles contributes to scientific progress in the area of personalized medicine and further stimulates the entering into clinical praxis of such new nanosystems.

Advances in Marine Chitin and Chitosan

Authors: ---
ISBN: 9783038421306 9783038421290 Year: Pages: XIV, 470 DOI: 10.3390/books978-3-03842-129-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2016-05-20 15:15:59
License:

Loading...
Export citation

Choose an application

Abstract

Recently, biomass-based polymers from renewable resources have received increasing focus owing to the depletion of petroleum resources. Natural polysaccharides such as cellulose,hemicellulose, and starch are among the candidates from natural resources for biomass polysaccharide products including bioplastics. Although several kinds of neutral or anionicpolysaccharides such as chitin, alginic acid, hyaluronic acid, heparin, and chondroitin sulfate exist in nature, natural cationic polysaccharides are quite limited. Chitin is second only tocellulose as the most natural abundant polysaccharide in the world. Chitosan, the product from the N-deacetylatation of chitin, appears to be the only natural cationic polysaccharide.Therefore, chitin and chitosan due to their unique properties are expected to continue to offer a vast number of possible applications for not only chemical or industrial use, but alsobiomedicine. The research history on chitins, one of the most major and abundant natural polysaccharides on earth, started around 1970. Since the 1980s, chitin and chitosan research(including D-glucosamine, N-acetyl-D-glucosamine, and their oligomers) has progressed significantly over several stages in both fundamental research and industrial fields.

Polymer Micelles

Authors: --- --- ---
ISBN: 9783038428077 9783038428084 Year: Pages: VIII, 220 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biochemistry
Added to DOAB on : 2018-04-20 15:30:28
License:

Loading...
Export citation

Choose an application

Abstract

Classically, polymer micelles have been defined as aggregates formed by the self-association of amphiphilic polymers due to the hydrophobic interactions between polymer molecules in water. Practical applications of polymer micelles include as carriers in drug delivery systems, as solubilizers, and as associative thickeners. Polymer micelles that do not fall within the classical definition have recently been reported and reflect important developments in synthesis and analysis. For example, hydrophobic interactions are the classic force driving polymer association, whereas recently, micelles have been formed through interactions such as electrostatics, hydrogen bonds, and coordination bonds. Intermolecular association results in the formation of polymer micelles that are similar to micelles formed from low molecular weight surfactants, whereas unimolecular micelles formed by intramolecular association within a single polymer chain have also been reported, as have stimuli-responsive polymer micelles. It is therefore important to constantly update the information available and our knowledge of polymer micelles. This special issue covers synthesis, characterization, solution properties, association behavior, simulation, and the application of polymer micelles and polymer aggregates. The aim of this issue is to expand our knowledge of polymer micelles by gathering together the latest basic and applied information regarding these supramolecular structures.

Marine Polysaccharides Volume 3

Author:
ISBN: 9783038429012 9783038429029 Year: Volume: 3 Pages: X, 564 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-04-24 09:32:36
License:

Loading...
Export citation

Choose an application

Abstract

The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailoring the production of bioactive compounds in a bioreactor. Of particular interest are polysaccharides produced by micro-organisms from extreme marine environments, due to their recognized different biochemistry. Extracellular polysaccharides (EPSs) with unique properties produced by a number of micro-algae are known. The first volume is a collection of papers concerning the identification and characterization of novel marine polysaccharides. It is divided into three chapters; the first two are dedicated to polysaccharides from different marine sources (algae, micro-algae, animals), while the third one gathers information on the isolation, characterization and bioactivity of new EPSs.

Marine Polysaccharides Volume 2

Author:
ISBN: 9783038428992 9783038429005 Year: Volume: 2 Pages: X, 290 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-04-24 09:35:54
License:

Loading...
Export citation

Choose an application

Abstract

The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailoring the production of bioactive compounds in a bioreactor. Of particular interest are polysaccharides produced by micro-organisms from extreme marine environments, due to their recognized different biochemistry. Extracellular polysaccharides (EPSs) with unique properties produced by a number of micro-algae are known. The first volume is a collection of papers concerning the identification and characterization of novel marine polysaccharides. It is divided into three chapters; the first two are dedicated to polysaccharides from different marine sources (algae, micro-algae, animals), while the third one gathers information on the isolation, characterization and bioactivity of new EPSs.

Marine Polysaccharides Volume 1

Author:
ISBN: 9783038428978 9783038428985 Year: Volume: 1 Pages: VIII, 224 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-04-24 09:38:37
License:

Loading...
Export citation

Choose an application

Abstract

The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailoring the production of bioactive compounds in a bioreactor. Of particular interest are polysaccharides produced by micro-organisms from extreme marine environments, due to their recognized different biochemistry. Extracellular polysaccharides (EPSs) with unique properties produced by a number of micro-algae are known. The first volume is a collection of papers concerning the identification and characterization of novel marine polysaccharides. It is divided into three chapters; the first two are dedicated to polysaccharides from different marine sources (algae, micro-algae, animals), while the third one gathers information on the isolation, characterization and bioactivity of new EPSs.

Selected Papers from 2017 International Conference on Micro/Nanomachines

Authors: ---
ISBN: 9783038970811 9783038970828 Year: Pages: VIII, 170 DOI: 10.3390/books978-3-03897-082-8 Language: english
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Sciences --- Mechanical Engineering
Added to DOAB on : 2018-08-09 17:08:18
License:

Loading...
Export citation

Choose an application

Abstract

The 2017 International Conference on Micro/Nanomachines (http://www.icmnm.org/) was held in Wuhan, China, 25–28 August, 2017. Micro/nanomotors (MNMs), which are defined as micro/nanodevices capable of converting energy into autonomous motion, can be used to pick up, transport, and release various cargoes within a liquid medium. They have important potential applications, for example, in drug delivery, biosensors, protein and cell separation, microsurgeries, and environment remediation. MNMs can be classified into two categories, according to their propulsion mechanism. In this respect, self-propelled MNMs are capable of moving autonomously without external intervention, but they either require toxic fuel or have a short lifespan. MNMs actuated by external fields, such as light, magnetic field, and acoustic waves, are not subject to these problems, do not require toxic fuels, nor give rise to by-products during the motion process. For both self-propelled and field-actuated MNMs, there is still a long way to go before we reach practical applications. The future development of MNMs should be focused on improving the energy conversion efficiency through structure optimization, exploring new propulsion mechanisms and endowing MNMs with environmental responses for self-navigation, detection, and specific operations. In this way, MNMs will approach their practical application in biomedicine, environment treatment, microengineering, etc.

Advances in Marine Chitin and Chitosan II, 2017

Authors: ---
ISBN: 9783038426776 9783038426783 Year: Pages: 410 DOI: 10.3390/books978-3-03842-678-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-01-16 09:37:31
License:

Loading...
Export citation

Choose an application

Abstract

As a result of our call in 2014 for submissions to a Special Issue, Advances in Marine Chitin and Chitosan in Marine Drugs, we are now pleased to tell you that this issue has been published. Twenty high class papers were included in this issue, which we now plan to publish as a book. In addition we now seek to publish a further Special Issue, Advances in Marine Chitin and Chitosan II, 2017, in Marine Drugs. As before, we plan to produce a strong, very exciting issue that will encompass breakthroughs in high value, scientific and industrial chitin and chitosan research. Despite significant advances in chitin and chitosan research since the 1970s, current overviews in recent publications involving chitin and chitosan research advances need reporting.

Translocator Protein (TSPO)

Authors: ---
ISBN: 9783038427575 9783038427582 Year: Pages: 176 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2018-03-16 13:21:14
License:

Loading...
Export citation

Choose an application

Abstract

The high number of papers submitted and ultimately accepted for publication in this special issue attests the great amount of research being conducted on TSPO and its role in living cells. Thus, TSPO has become an extremely attractive subcellular biomark for the early detection of disease states overexpressing this protein and for the selective delivery to mitochondria of drugs and probes. Moreover, the effort in the design and synthesis of new, more specific and effective TSPO ligands proves to be very valuable. All these topics have been addressed in the special issue.

Listing 1 - 10 of 45 << page
of 5
>>
Sort by
Narrow your search

Publisher

MDPI - Multidisciplinary Digital Publishing Institute (45)


License

CC by-nc-nd (42)

CC by (2)

CC by-nc-sa (1)


Language

english (38)

eng (7)


Year
From To Submit

2020 (18)

2019 (16)

2018 (9)

2015 (2)