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Nuclear Magnetic Resonance Spectroscopy

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ISBN: 9783038429937 9783038429944 Year: Pages: X, 298 Language: englisch
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-08-21 14:42:20
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Nuclear Magnetic Resonance (NMR) spectroscopy is a nondestructive technique that can be used to characterize a wide variety of systems. Sustained development of both methodology and instrumentation have allowed NMR to evolve as a powerful technology, with applications in pure sciences, medicine, drug development, and important branches of industry. NMR provides precise structural information down to each atom and bond in a molecule, and is the only method for the determination of structures of molecules in a solution. This book compiles a series of articles describing the application of NMR in a variety of interesting scientific challenges. The articles illustrate the versatility and flexibility of NMR.

An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2

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ISBN: 9783038424130 9783038424123 Year: Pages: 320 DOI: 10.3390/books978-3-03842-413-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2017-07-12 07:57:21
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The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6–9 September, 2016.Protein kinase CK2 is a serine/threonine kinase, which is highly conserved in evolution. Knock-out experiments have shown that this enzyme is absolutely necessary for cell viability. The enzyme is highly expressed in rapidly proliferating cells, which goes along with an elevated enzyme activity. Protein kinase CK2 is involved in a broad range of signaling pathways, regulating proliferation, differentiation, apoptosis, or senescence. Recent advances towards the characterization of the three-dimensional structure of protein kinase CK2 and its subunits will undoubtedly yield important new insights into its regulation, and the functions of CK2. Moreover, with two inhibitors of the enzyme presently in clinical phase II trials, human protein kinase CK2 has appeared as an emerging target for cancer diseases.

Rietveld Refinement in the Characterization of Crystalline Materials

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ISBN: 9783038975274 9783038975281 Year: Pages: 88 DOI: 10.3390/books978-3-03897-528-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General) --- Analytical Chemistry
Added to DOAB on : 2019-01-28 10:16:11
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This Special Issue serves as a crystallographic forum covering various aspects of material science that have in common the use of the powerful Rietveld method in the analysis of the powder XRD patterns of investigated compounds.

Viral Replication Complexes: Structures, Functions, Applications and Inhibitors

ISBN: 9783038421672 9783038421689 Year: Pages: XVI, 428 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-07-14 07:43:51
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Viruses are obligate intracellular parasites that need to co-opt a living cell’s machinery for replication. At the heart of the viral replication machinery are the nucleic acid polymerases, which are responsible for efficiently copying the viral genome. This process must often be coordinated with other viral processes including protein translation and viral packaging. The nucleic acid polymerases may also be responsible for generating genetic diversity that is important for escape from the host’s defenses. The polymerases and other components of the replication machinery may serve as potential anti-viral targets. In this Special Issue, we seek to highlight recent advances into uncovering the structure and function of viral replication complexes. We are especially seeking to highlight the wide-range of methodologies used to gain structural insight into viral replication. Topics of interest include molecular mechanisms of nucleic acid polymerases, nucleic acid recognition and translocation, fidelity and error correction, interactions with lipid membranes, and coordination/regulation of transcription, translation and replication processes.

Biomass Chars: Elaboration, Characterization and Applications

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ISBN: 9783038426905 9783038426912 Year: Pages: 220 DOI: 10.3390/books978-3-03842-691-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-01-12 11:37:17
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Thermochemical conversion processes convert biomass into gaseous, liquid and solid products named, syngas, bio-oil and char, respectively. Syngas and bio-oil are considered as alternative biofuels to fossil fuels and wide investigations are implemented currently on their production, purification, modification, and applications. Biomass chars have receiving an increasing attention since they lead to carbon sequestration, reduction of the amount of carbon rejected into the atmosphere and represent an friendly carbon source for numerous applications. In particular, biomass chars could be an efficient materials for energy production, syngas production and upgrading, water and air pollutants removal, soil amendment, fuel cells and supercapacitors development, and gas storage. Improving the knowledge of biomass chars elaboration techniques such as pyrolysis, gasification and hydrothermal carbonization is essential to determine the optimal production strategies for their economic viability. Furthermore, the characterization of the physicochemical, textural, structural and surface chemistry properties of the derived chars guide the selection of the suitable recovery processes in order to maximize their utility and therefore the benefits for the environment as well as for industries and agriculture.

Structural Design and Properties of Coordination Polymers

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ISBN: 9783038428015 9783038428022 Year: Pages: VIII, 122 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-04-27 13:20:05
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Dear Colleagues,The assembly of organic ligands and metal centres yields coordination polymers, many of which find applications in conductivity, catalysis, magnetism, gas sorption, biological sensing and luminescence. The structure and topology of coordination polymers may be manipulated by changing the reaction conditions, leading to a large variety of structurally and topologically unique products. However, controlling and predicting the final outcome of the self-assembly procedure remains one of the major challenges in the field. The final products are often strongly influenced by factors such as the behaviour of a functional group in a molecule, the influence of the crystallization conditions and the various conformations of the components within the crystal.This Special Issue aims to cover a broad range of subjects in coordination polymer chemistry, which are important to the continued growth of the field, showcase current developments and realise its full potential in applications to address major societal challenges.Therefore, we invite you to contribute a research article to this Special Issue and provide a clear snapshot of your research in this field.

Design and Applications of Coordinate Measuring Machines

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ISBN: 9783038422761 9783038422778 Year: Pages: XII, 198 DOI: 10.3390/books978-3-03842-277-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering
Added to DOAB on : 2016-11-11 18:50:12
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Coordinate measuring machines (CMMs) have been conventionally used in industry for 3-dimensional and form-error measurements of macro parts for many years. Ever since the first CMM, developed by Ferranti Co. in the late 1950s, they have been regarded as versatile measuring equipment, yet many CMMs on the market still have inherent systematic errors due to the violation of the Abbe Principle in its design. Current CMMs are only suitable for part tolerance above 10 μm. With the rapid advent of ultraprecision technology, multi-axis machining, and micro/nanotechnology over the past twenty years, new types of ultraprecision and micro/nao-CMMs are urgently needed in all aspects of society.This Special Issue accepted papers revealing novel designs and applications of CMMs, including structures, probes, miniaturization, measuring paths, accuracy enhancement, error compensation, etc. Detailed design principles in sciences, and technological applications in high-tech industries, were required for submission.Topics covered, but were not limited to, the following areas:1.New types of CMMs, such as Abbe-free, multi-axis, cylindrical, parallel, etc.2.New types of probes, such as touch-trigger, scanning, hybrid, non-contact, microscopic, etc.3.New types of Micro/nano-CMMs.4.New types of measuring path strategy, such as collision avoidance, free-form surface, aspheric surface, etc.5.New types of error compensation strategy.

Structural Health Monitoring (SHM) of Civil Structures

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ISBN: 9783038427834 9783038427841 Year: Pages: X, 490 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering
Added to DOAB on : 2018-04-20 14:47:20
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At the current time of writing, the American Society of Civil Engineers (ASCE) has awarded American infrastructure a grade of D+, meaning poor and at risk. Part of the reason for the low grade is due to the rapid deterioration of structural integrity and the inability of most places to safely meet future demands. Deficiencies in these areas may be remediated by advancements in structural health monitoring (SHM) technologies that provide sensing systems to automatically and economically diagnose structural integrity. In a sense, SHM technologies will help pave the way to intelligent structures that are able to detect damage by themselves and even warn occupants of any danger due to impending structural failure. Engineering sensors and developing smart algorithms for SHM often involves the close collaboration of a surprisingly large breadth of specialties. In this book, we have collected a thin but representative slice of the most recent research in SHM, and hope that the reader will gain an inspiring view of today’s research landscape and a notion of what is to come.

X-Ray Free-Electron Laser

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ISBN: 9783038428794 9783038428800 Year: Pages: XII, 454 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Physics (General)
Added to DOAB on : 2018-07-04 14:02:12
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X-ray free electron lasers (XFELs) deliver intense, coherent, femtosecond laser pulses in the X-ray range. The XFELs are opening two new research fields. One is to study ultrafast electronic and structural dynamics in various forms of matter. XFELs can make atoms and electrons in action visible. Another field is to study the non-linear interaction of the unprecedented intense X-ray pulse with matter. XFELs transform matter into its new form in extreme conditions that have never been reached. The present special issue provides an overview of the current status and future direction of the development of XFELs and the research fields opened by XFELs. Featured are reports on the status and plans of all FEL facilities in the world, i.e., FLASH in Germany, LCLS in USA, SACLA in Japan, FERMI in Italy, European XFEL, SwissFEL, PAL-XFEL in Korea, and Shanghai SXFEL in China. Reports are also included on instrumentations and on science at these facilities, as well as on the relevant theory.

Mechanical Behaviour of Aluminium Alloys

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ISBN: 9783038973201 9783038973218 Year: Pages: 144 DOI: 10.3390/books978-3-03897-321-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Materials --- Mechanical Engineering
Added to DOAB on : 2018-12-10 12:04:07
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ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[Aluminium alloys are the most common non-ferrous materials utilised for a wide range of engineering applications, namely, automotive, aerospace, mould and structural industries, among others. The wide spread of these alloys in the modern word is due to the unique combination of material properties combining lightness, excellent strength, corrosion resistance, toughness, electrical and thermal conductivity, recyclability, and manufacturability. Last but not least, the relatively low cost of aluminium extrusion is important as it makes aluminium alloys very attractive for applications in different key sectors of the world economy. Despite great interest, extensive previous research, and knowledge accumulated in the past, recent advances in production and processing technologies, combined with the development of new and more ingenious and competitive products, require a profound understanding of the physical and mechanical behaviour of such alloys, specifically in terms of modelling and predictions of the fracture and fatigue life of aluminium alloy components. This Special Issue aims to gather scientific contributions from authors working in different scientific areas, including the improvement and modelling of mechanical properties, alloying design and manufacturing techniques, the characterization of microstructure and chemical composition, and advanced applications.

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