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Regulation of Chemokine- Receptor Interactions and Functions

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ISBN: 9783038427285 9783038427278 Year: Pages: 228 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biochemistry
Added to DOAB on : 2018-03-26 15:44:06
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A hallmark of inflammation is the accumulation of leukocytes, which can serve to remove pathogens and necrotic tissue, but may also damage healthy tissue and exacerbate the inflammatory response. Our understanding of leukocyte recruitment in inflammation was revolutionized in the late 1980s by the discovery of chemokines (chemotactic cytokines), a family of small, secreted proteins that induce migration of selective subsets of leukocytes. Shortly afterwards, chemokines were found to exert their functions through the now familiar chemokine receptors, members of the G protein-coupled receptor superfamily. As their physiological and pathological functions were elucidated, chemokine receptors have become popular targets for drug development in inflammatory diseases as well as cancer metastasis and HIV infection. Extensive research has revealed that the functions of chemokines and their receptors are regulated at numerous levels, including: genetic mutations/polymorphisms; control of expression levels; ligand internalization via functional or decoy receptors; intrinsic selectivity of chemokine-receptor binding; hetero- or homo-oligomerization of chemokines or of receptors; alternative signalling pathways; interaction of chemokines with glycosaminoglycans; post-translational modifications; and binding to pathogen-derived inhibitors. This Special Issue of IJMS focused on the natural and pharmacological mechanisms by which the activities of chemokines and their receptors can be regulated.

Acupuncture – Basic Research and Clinical Application

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ISBN: 9783038972341 9783038972358 Year: Pages: 170 DOI: 10.3390/books978-3-03897-235-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2018-10-09 11:13:34
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This book focuses on the investigation, development, and modernization of acupuncture in basic research settings as well as in clinical applications. The book contains 13 chapters reporting the latest evidence-based results of acupuncture research and exploring acupuncture in general. Altogether, 44 authors from all over the world contributed to this book.

Human Factors in Green Building

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ISBN: 9783038975663 9783038975670 Year: Pages: 200 DOI: 10.3390/books978-3-03897-567-0
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Construction --- Architecture
Added to DOAB on : 2019-01-23 09:42:11
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World Green Building Council suggests that health, well-being and productivity should be the next chapter for green building. There is an obvious shift of green building movement from technology-centric towards human-centric, which culminates in recent WELL Building Standard, focusing exclusively on human health and wellness. This special issue aims to push forward the research, discourse and practice of green building towards more human-oriented design solutions. Particularly, this special issue collects papers on: Post-occupancy evaluation of green buildingsIndoor Environmental Quality (IEQ)Thermal Comfort and Adaptive BehaviorsQuality of Life and HousingHealthcare Design

Asymmetric Planetary Nebulae VII

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ISBN: 9783038976400 Year: Pages: 204 DOI: 10.3390/books978-3-03897-641-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Physics (General) --- Astronomy (General)
Added to DOAB on : 2019-03-21 14:08:22
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This book contains the best and most up-to-date contributions in the field of late stage stellar evolution, as presented at the APNVII conference in Hong Kong in December 2017. A total of 60 scientists from 20 countries gathered to present, listen, interact and discuss the most current issues and problems in planetary nebulae and related objects research. The emphasis of this influential series of meetings, which was the seventh occasion over the last 20 years, has always been on the hypothesized and observed physical shaping mechanisms of the ejected nebulae that have such wonderful and intriguing forms. This special Galaxies conference issue of fully refereed contributions brings together a representative compilation of the meeting presentations in paper form. It captures the current “snap shot” status of this research field in some real sense. Such proceedings are well received and can be used as a reference material by both participants and all others working in the field for years to come.

Keywords

planetary systems --- planetary nebulae --- stars: binaries --- stars: AGB and post-AGB --- stars: variables: general --- stars: abundances --- stars: AGB and post-AGB --- stars: atmospheres --- stars: individual: WD 0044–121 --- stars: individual: WD 2134+25 --- stars: individual: WD 1751+106 --- planetary nebulae --- asymptotic giant branch stars --- mass loss --- infra-red --- planetary nebulae --- integral field spectroscopy --- stellar evolution --- binarity --- planetary nebulae --- stellar mass loss --- stellar evolution --- planetary nebulae --- circumstellar dust --- planetary nebulae --- mass-loss --- stellar evolution --- X-rays --- stellar evolution --- late stage stellar evolution --- binarity: transients: planetary nebulae --- planetary nebulae --- stars: AGB and post-AGB --- late stage stellar evolution --- planetary nebulae --- stars: binaries --- central stars of planetary nebulae --- proto-planetary nebulae --- binaries: spectroscopic --- stars: atmospheres --- stars: abundances --- supernovae --- late stage stellar evolution --- planetary nebulae --- binarity --- stellar evolution --- AGB and post-AGB stars --- circumstellar matter --- winds and outflows --- mass-loss --- jets --- binaries: close --- stars: AGB and post-AGB --- stars: winds, outflows --- ISM: jets and outflows --- binary stars --- post-AGB --- discs --- planetary nebula --- X-ray --- stellar evolution --- AGB stars --- post-AGB stars --- planetary nebulae --- planetary nebulae --- fullerenes --- planetary nebulae --- AGB and post-AGB stars --- binarity --- accretion disks --- jets --- mass-loss --- circumstellar matter --- (sub)millimeter interferometry --- ultraviolet radiation, X-rays --- infrared interferometry --- AGB stars --- stellar evolution --- observations --- aperture masking --- planetary nebulae --- binarity --- abundances --- stellar evolution --- post-AGB stars --- pre-PN hydrodynamic models --- planetary nebulae: Common Envelope --- planetary nebulae: individual (OH231+8+04.2) --- astrochemistry --- planetary nebulae --- UIE bands --- normal modes --- displacement vectors --- late-stage stellar evolution --- planetary nebulae --- multi-wavelength photometry --- radial velocity --- stellar evolution --- pulsation --- shock wave --- late stage stellar evolution --- planetary nebulae --- theory and observation --- planetary nebulae --- AGB and post-AGB --- interstellar medium --- radio continuum --- winds --- outflows --- dust --- extinction --- ISM: abundances --- planetary nebulae: individual (NGC 6781)

Tourism Destination Management

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ISBN: 9783039214716 9783039214723 Year: Pages: 122 DOI: 10.3390/books978-3-03921-472-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Economics
Added to DOAB on : 2019-12-09 11:49:15
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This book collected studies focused on the management of tourist destinations. Destinations are complex and adaptive systems, where the different elements that make them up have to be oriented towards achieving a common objective that improves the competitiveness of the destination. Five main lines of research on tourist destinations can be established: 1) the management, planning, and marketing of destinations, with special attention to the tourism supply chain, communication, and integral management; 2) the sustainability of resources and capabilities; 3) the renewal of destinations in order to update their offer and main resources to maintain competitiveness; 4) online reputation and communication through social media in order to create and enhance a strong brand image and customer loyalty; and 5) the application of new technologies in order to develop smart destinations. The book is made up of five research studies that focus on analyzing the transition towards a more circular tourist activity in hotels, image as a competitive factor of destinations, the value of cultural creativity, the coherence of online reputation, and the relationship between hotel prices and online reputation in different tourist destinations.

Cyberpunk in a Transnational Context

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ISBN: 9783039214211 9783039214228 Year: Pages: 122 DOI: 10.3390/books978-3-03921-422-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Arts in general --- Performing Arts
Added to DOAB on : 2019-12-09 11:49:15
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Mike Mosher’s “Some Aspects of Californian Cyberpunk” vividly reminds us of the influence of West Coast counterculture on cyberpunks, with special emphasis on 1960s theoretical gurus such as Timothy Leary and Marshall McLuhan, who explored the frontiers of inner space as well as the global village. Frenchy Lunning’s “Cyberpunk Redux: Dérives in the Rich Sight of Post-Anthropocentric Visuality” examines how the heritage of Ridley Scott’s techno-noir film

Religion and Art: Rethinking Aesthetic and Auratic Experiences in 'Post-Secular' Times

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ISBN: 9783039210329 9783039210336 Year: Pages: 102 DOI: 10.3390/books978-3-03921-033-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-06-26 08:44:06
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How can we think of the “aura” of (sacred) contexts and (sacred) works? How to think of individual and collective (esthetic/religious) experiences? What to make of the manipulative dimension of (religious and esthetic) “auratic” experiences? Is the work of art still capable of mediating the experience of the “sacred,” and under what conditions? What is the significance of the “eschatological” dimension of both art and religion (the sense of “ending”)? Can theology offer a way to reaffirm the creative capacities of the human being as something that characterizes the very condition of being human? This Special Issue aspires to contribute to the growing literature on contemporary art and religion, and to explore the new ways of thinking of art and the sacred (in their esthetic, ideological, and institutional dimensions) in the context of contemporary culture.

The Sacred & the Digital. Critical Depictions of Religions in Video Games

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ISBN: 9783038978305 9783038978312 Year: Pages: 184 DOI: 10.3390/books978-3-03897-831-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-04-25 16:37:17
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Video game studies are a relative young but flourishing academic discipline. But within game studies, however, the perspective of religion and spirituality is rather neglected, both by game scholars and religion scholars. While religion can take different shapes in digital games, ranging from material and referential to reflexive and ritual, it is not necessarily true that game developers depict their in-game religions in a positive, confirming way, but ever so often games approach the topic critically and disavowingly. The religion criticisms found in video games can be categorized as follows: religion as (1) fraud, aimed to manipulate the uneducated, as (2) blind obedience towards an invisible but ultimately non-existing deity/ies, as (3) violence against those who do not share the same set of religious rules, as (4) madness, a deranged alternative for logical reasoning, and as (5) suppression in the hands of the powerful elite to dominate and subdue the masses into submission and obedience. The critical depictions of religion in video games by their developers is the focus of this special issue.

Environmental Enrichment of Pigs

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ISBN: 9783039280780 9783039280797 Year: Pages: 174 DOI: 10.3390/books978-3-03928-079-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Animal Sciences
Added to DOAB on : 2020-04-07 23:07:08
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Pigs have a strong motivation to explore and root. In conventional pig husbandry systems, this need is difficult to fulfil, unless adequate enrichment materials are provided. This book summarises how enrichment strategies for pigs have evolved over the last few decades in different countries and provides a vast array of possibilities to enhance the exploratory needs of pigs. The role of enrichment material on avoidance of tail biting outbreaks or as an element triggering positive emotions in pigs is also discussed.

Side Channel Attacks

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ISBN: 9783039210008 9783039210015 Year: Pages: 258 DOI: 10.3390/books978-3-03921-001-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-06-26 08:44:06
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This Special Issue provides an opportunity for researchers in the area of side-channel attacks (SCAs) to highlight the most recent exciting technologies. The research papers published in this Special Issue represent recent progress in the field, including research on power analysis attacks, cache-based timing attacks, system-level countermeasures, and so on.

Keywords

cache attack --- cache side-channel attack --- constant-time cryptographic algorithm --- rsa cryptosystem --- scatter-gather implementation --- modular exponentiation --- post-quantum cryptography --- lattice-based cryptography --- Gaussian sampling --- CDT sampling --- side-channel attack --- single trace analysis --- mobile ads --- software development kit (SDK), android package (APK), ad lib --- ad libraries --- ad networks --- graph --- graph similarity --- side-channel authentication --- leakage model --- AES --- FPGA --- unified point addition --- binary Huff curve --- recovery of secret exponent by triangular trace analysis --- horizontal collision correlation analysis --- side channel analysis --- single trace analysis --- post quantum cryptography --- NTRU --- side-channel analysis --- elliptic curve cryptography --- single-trace attack --- key bit-dependent attack --- countermeasure --- side channel analysis --- financial IC card --- first-order analysis --- second-order analysis --- data outsourcing --- integrity --- online authentication --- Merkle (hash) tree --- data loss --- information leakage --- reliability --- side-channel analysis --- power-analysis attack --- embedded system security --- machine-learning classification --- side-channel cache attacks --- cache misses --- AES --- cloud computing --- physically unclonable function --- chaos theory --- chaotic circuit --- FPGA --- CPLD --- challenge-response authentication --- hardware security --- side-channel attacks --- cryptographic keys --- side channel attack --- re-keying --- tweakable block cipher --- provable security --- n/a

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