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Statistical Population Genomics

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Book Series: Methods in Molecular Biology ISBN: 9781071601990 Year: Pages: 468 DOI: 10.1007/978-1-0716-0199-0 Language: English
Publisher: Springer
Subject: Biology
Added to DOAB on : 2020-01-29 11:21:12
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This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions.

Pre-Field Screening Protocols for Heat-Tolerant Mutants in Rice

Authors: --- --- --- --- et al.
ISBN: 9783319773384 Year: Pages: 39 DOI: 10.1007/978-3-319-77338-4 Language: English
Publisher: Springer
Subject: Agriculture (General) --- Botany
Added to DOAB on : 2020-02-04 11:21:03
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This open access book presents simple, robust pre-field screening protocols that allow plant breeders to screen for enhanced tolerance to heat stress in rice. Two critical heat-sensitive stages in the lifecycle of the rice crop are targeted – the seedling and flowering stages – with screening based on simple phenotypic responses. The protocols are based on the use of a hydroponics system and/or pot experiments in a glasshouse in combination with a controlled growth chamber where the heat stress treatment is applied. The protocols are designed to be effective, simple, reproducible and user-friendly. The protocols will enable plant breeders to effectively reduce the number of plants from a few thousands to less than 100 candidate individual mutants or lines in a greenhouse/growth chamber, which can then be used for further testing and validation in the field conditions. The methods can also be used to classify rice genotypes according to their heat tolerance characteristics. Thus, different types of heat stress tolerance mechanisms can be identified, presenting opportunities for pyramiding different (mutant) sources of heat stress tolerance.

Evolutionary Genomics

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Book Series: Methods in Molecular Biology ISBN: 9781493990740 Year: Pages: 780 DOI: 10.1007/978-1-4939-9074-0 Language: English
Publisher: Springer
Subject: Biology
Added to DOAB on : 2020-01-29 11:21:11
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This open access book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results. Authoritative and comprehensive, Evolutionary Genomics: Statistical and Computational Methods, Second Edition aims to serve both novices in biology with strong statistics and computational skills, and molecular biologists with a good grasp of standard mathematical concepts, in moving this important field of study forward.

Linear Selection Indices in Modern Plant Breeding

Authors: ---
ISBN: 9783319912233 Year: Pages: 256 DOI: 10.1007/978-3-319-91223-3 Language: English
Publisher: Springer
Subject: Zoology --- Botany --- Biology
Added to DOAB on : 2020-02-05 11:21:15
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This open access book focuses on the linear selection index (LSI) theory and its statistical properties. It addresses the single-stage LSI theory by assuming that economic weights are fixed and known - or fixed, but unknown - to predict the net genetic merit in the phenotypic, marker and genomic context. Further, it shows how to combine the LSI theory with the independent culling method to develop the multistage selection index theory. The final two chapters present simulation results and SAS and R codes, respectively, to estimate the parameters and make selections using some of the LSIs described. It is essential reading for plant quantitative geneticists, but is also a valuable resource for animal breeders.

Bird Species

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Book Series: Fascinating Life Sciences ISBN: 9783319916897 Year: Pages: 266 DOI: 10.1007/978-3-319-91689-7 Language: English
Publisher: Springer
Subject: Zoology --- Biology
Added to DOAB on : 2020-02-05 11:21:16
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The average person can name more bird species than they think, but do we really know what a bird “species” is? This open access book takes up several fascinating aspects of bird life to elucidate this basic concept in biology. From genetic and physiological basics to the phenomena of bird song and bird migration, it analyzes various interactions of birds – with their environment and other birds. Lastly, it shows imminent threats to birds in the Anthropocene, the era of global human impact. Although it seemed to be easy to define bird species, the advent of modern methods has challenged species definition and led to a multidisciplinary approach to classifying birds. One outstanding new toolbox comes with the more and more reasonably priced acquisition of whole-genome sequences that allow causative analyses of how bird species diversify. Speciation has reached a final stage when daughter species are reproductively isolated, but this stage is not easily detectable from the phenotype we observe. Culturally transmitted traits such as bird song seem to speed up speciation processes, while another behavioral trait, migration, helps birds to find food resources, and also coincides with higher chances of reaching new, inhabitable areas. In general, distribution is a major key to understanding speciation in birds. Examples of ecological speciation can be found in birds, and the constant interaction of birds with their biotic environment also contributes to evolutionary changes. In the Anthropocene, birds are confronted with rapid changes that are highly threatening for some species. Climate change forces birds to move their ranges, but may also disrupt well-established interactions between climate, vegetation, and food sources. This book brings together various disciplines involved in observing bird species come into existence, modify, and vanish. It is a rich resource for bird enthusiasts who want to understand various processes at the cutting edge of current research in more detail. At the same time it offers students the opportunity to see primarily unconnected, but booming big-data approaches such as genomics and biogeography meet in a topic of broad interest. Lastly, the book enables conservationists to better understand the uncertainties surrounding “species” as entities of protection.

Self-Reported Population Health: An International Perspective based on EQ-5D

Authors: --- ---
ISBN: 9789400775954 9789400775961 Year: Pages: 212 DOI: 10.1007/978-94-007-7596-1 Language: English
Publisher: Springer
Subject: Public Health --- Biotechnology --- Pharmacy and materia medica --- Medicine (General)
Added to DOAB on : 2014-07-25 14:27:36
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The EQ-5D instrument, as a standardized, cross-culturally validated measure of self-assessed health has a hugely important role in understanding population health within and across countries. Over the past two decades a wealth of international population health survey data have been accumulated by the EuroQol Group from research conducted in many countries across four continents. One of the success factors of the EQ-5D instruments has been the easy availability of national or international sets of EQ-5D data, as well as clear explanations and guidance for users. There is an unmet need to produce a comprehensive book that captures up-to-date and expanded information of EQ-5D self-reported health and index values. EQ-5D population norms and cross-country analyses are provided from representative national surveys of 20 countries and additional regional surveys. This book will be a must for those who believe that how people report and value health is very important.

Designing Sustainable Technologies, Products and Policies

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ISBN: 9783319669809/9783319669816 Year: Volume: 1 Pages: 520 DOI: https://doi.org/10.1007/978-3-319-66981-6 Language: English
Publisher: Springer
Subject: Environmental Engineering
Added to DOAB on : 2019-09-10 16:32:12
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This open access book provides insight into the implementation of Life Cycle approaches along the entire business value chain, supporting environmental, social and economic sustainability related to the development of industrial technologies, products, services and policies; and the development and management of smart agricultural systems, smart mobility systems, urban infrastructures and energy for the built environment. The book is based on papers presented at the 8th International Life Cycle Management Conference that took place from September 3-6, 2017 in Luxembourg, and which was organized by the Luxembourg Institute of Science and Technology (LIST) and the University of Luxembourg in the framework of the LCM Conference Series.

The Social Metabolism of Spanish Agriculture, 1900–2008

Authors: --- --- --- --- et al.
Book Series: Environmental History ISBN: 9783030209001 Year: Pages: 281 DOI: 10.1007/978-3-030-20900-1 Language: English
Publisher: Springer
Subject: Agriculture (General) --- Economics --- Environmental Sciences --- History
Added to DOAB on : 2020-02-04 11:21:10
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This open access book provides a panoramic view of the evolution of Spanish agriculture from 1900 to the present, offering a more diverse picture to the complex and multidimensional reality of agrarian production. With a clear transdisciplinary ambition, the book applies an original and innovative theoretical and methodological tool, termed Agrarian Social Metabolism, combining Social Metabolism with an agroecological perspective. This integrative analysis is especially interesting for environmental scientists and policy makers being the best way to design sustainable agroecosystems and public policies capable of moving us towards a more sustainable food system. Spanish agricultural production has experienced impressive growth during the 20th century which has allowed it to ensure the supply of food to the population and even to transform some crops into important chapters in foreign trade. However, this growth has had its negative side since it was based on the injection of large amounts of external energy, on the destruction of employment and the loss of profitability of agricultural activity. But perhaps the most serious part is the strong impact of the current industrialised agriculture model on Spanish agroecosystems, exposed to the overexploitation of hydric resources, pollution of the water by nitrates and pesticides, high erosion rates and an alarming loss of biodiversity; damage which in the immediate future will end up reducing production capacity.

The Potato Crop

Authors: ---
ISBN: 9783030286835 Year: Pages: 518 DOI: 10.1007/978-3-030-28683-5 Language: English
Publisher: Springer
Subject: Agriculture (General) --- Chemical Technology --- Botany --- Biology
Added to DOAB on : 2020-02-04 11:21:17
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Life sciences; Agriculture; Nutrition   ; Plant breeding; Food—Biotechnology; Agricultural economics

Sequence Analysis and Related Approaches

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Book Series: Life Course Research and Social Policies ISBN: 9783319954202 Year: Pages: 298 DOI: 10.1007/978-3-319-95420-2 Language: English
Publisher: Springer
Subject: Economics --- Sociology
Added to DOAB on : 2020-02-04 11:21:19
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This open access book provides innovative methods and original applications of sequence analysis (SA) and related methods for analysing longitudinal data describing life trajectories such as professional careers, family paths, the succession of health statuses, or the time use. The applications as well as the methodological contributions proposed in this book pay special attention to the combined use of SA and other methods for longitudinal data such as event history analysis, Markov modelling, and sequence network. The methodological contributions in this book include among others original propositions for measuring the precarity of work trajectories, Markov-based methods for clustering sequences, fuzzy and monothetic clustering of sequences, network-based SA, joint use of SA and hidden Markov models, and of SA and survival models. The applications cover the comparison of gendered occupational trajectories in Germany, the study of the changes in women market participation in Denmark, the study of typical day of dual-earner couples in Italy, of mobility patterns in Togo, of internet addiction in Switzerland, and of the quality of employment career after a first unemployment spell. As such this book provides a wealth of information for social scientists interested in quantitative life course analysis, and all those working in sociology, demography, economics, health, psychology, social policy, and statistics. ; Provides new perspectives and methods for sequence analysis Focusses on the link between sequence analysis and other methods for longitudinal data, especially event history analysis and Markov models Stresses the complementarity of sequence analysis and other models for longitudinal data Applications of sequence analysis in a whole range of different domains

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