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Tissue Engineering may offer new treatment alternatives for organ replacement or repair deteriorated organs. Among the clinical applications of Tissue Engineering are the production of artificial skin for burn patients, tissue engineered trachea, cartilage for knee-replacement procedures, urinary bladder replacement, urethra substitutes and cellular therapies for the treatment of urinary incontinence. The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues reconstructed from readily available biopsy material induce only minimal or no immunogenicity when reimplanted in the patient. This book is aimed at anyone interested in the application of Tissue Engineering in different organ systems. It offers insights into a wide variety of strategies applying the principles of Tissue Engineering to tissue and organ regeneration.

Health Sciences --- Medicine --- Biomedical Engineering --- Tissue Engineering and Regenerative Medicine

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Tissue engineering, which aims at regenerating new tissues, as well as substituting lost organs by making use of autogenic or allogenic cells in combination with biomaterials, is an emerging biomedical engineering field. There are several driving forces that presently make tissue engineering very challenging and important: 1) the limitations in biological functions of current artificial tissues and organs made from man-made materials alone, 2) the shortage of donor tissue and organs for organs transplantation, 3) recent remarkable advances in regeneration mechanisms made by molecular biologists, as well as 4) achievements in modern biotechnology for large-scale tissue culture and growth factor production. This book was edited by collecting all the achievement performed in the laboratory of oral and maxillofacial surgery and it brings together the specific experiences of the scientific community in these experiences of our scientific community in this field as well as the clinical experiences of the most renowned experts in the fields from all over Nagoya University. The editors are especially proud of bringing together the leading biologists and material scientists together with dentist, plastic surgeons, cardiovascular surgery and doctors of all specialties from all department of the medical school of Nagoya University. Taken together, this unique collection of world-wide expert achievement and experiences represents the current spectrum of possibilities in tissue engineered substitution.

Health Sciences --- Medicine --- Biomedical Engineering --- Tissue Engineering and Regenerative Medicine