Search results: Found 2

Listing 1 - 2 of 2
Sort by
Mass Spectrometry Application in Biology

ISBN: 9783906980898 9783906980904 Year: Pages: 252 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2015-10-22 06:39:08
License:

Loading...
Export citation

Choose an application

Abstract

Mass spectrometry (MS) has become a vital tool for scientist in exploring how biological systems function and how therapeutic drug intervention (both small molecules and biologics) impact these systems. The application of mass spectrometry has advanced our knowledge in the biological sciences through the study of proteins and peptides in proteomics and as biomarkers, imaging via MALDI MS, and analysis of SNP’s in the genome to allow personalized medical treatment.The aim of this book is to provide a glimpse of some of the many applications of the advancing field of mass spectrometry and its application to complex biological problems. The topics presented here touch on many of the areas listed above will hopefully serve as a catalyst to generate new ideas for the continued innovative application of mass spectrometry to the fields of medicine, biology and beyond.

Clinical use of biomarkers in neurodegenerative disorders

Author:
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889194001 Year: Pages: 122 DOI: 10.3389/978-2-88919-400-1 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2015-12-10 11:59:06
License:

Loading...
Export citation

Choose an application

Abstract

The prevalence of neurodegenerative disorders is increasing dramatically and one of the major challenges today is the need of early and accurate diagnosis, the other is the need of more effective therapies -in turn the development of such therapies also requires early and accurate diagnosis-. The main hope for an earlier and more accurate diagnosis comes from the use of biomarkers. Much research is being done trying to solve the many interrogates related to the role of biomarkers in clinical practice, including the early diagnosis, differential diagnosis and follow-up of neurodegenerative disorders. This is a field where translational research is intense enough to make this topic interesting for basic researchers and clinicians. Indeed, the amount and quality of articles received in response to the call for contributions was very good. This eBook contains a good amount of high quality articles devoted to diverse techniques across several neurodegenerative disorders from different perspectives, including original reports, reviews, methods reports and opinion letters on biochemical biomarkers in biological fluids, neuroimaging techniques and multidimensional approaches linking clinical findings with biomarkers. The disorders covered are also diverse: Alzheimer’s disease, Frontotemporal Dementia, Dementia with Lewy Bodies, Huntington’s disease, Parkinson’s disease among others. As we can learn from articles in this Research Topic, biomarkers are allowing us to expand the knowledge on the biological and anatomical basis of neurodegenerative diseases and to implement diagnostic techniques in clinical practice and clinical trials.

Listing 1 - 2 of 2
Sort by
Narrow your search

Publisher

Frontiers Media SA (1)

MDPI - Multidisciplinary Digital Publishing Institute (1)


License

CC by (1)

CC by-nc-nd (1)


Language

english (2)


Year
From To Submit

2014 (2)