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Toxicology Studies - Cells, Drugs and Environment

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ISBN: 9789535121404 9789535142201 Year: Pages: 244 DOI: 10.5772/58714 Language: English
Publisher: IntechOpen
Subject: Public Health
Added to DOAB on : 2019-10-03 07:51:49

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The increased exposure to toxins, toxicants and novel drugs has promoted toxicology to become one of the most important areas of research with emerging innovative toxicity testing protocols, techniques, and regulation being placed. Since the bioactivation of many toxins and toxicants and its consequences on human health are not clearly known, this book offers a quick overview of cellular toxicology through the cell, drug and environmental toxicity. This book does not strive to be comprehensive but instead offers a quick overview of principle aspects of toxins and toxicants in order to familiarize the key principles of toxicology. The book is divided into three main sections,; the first one discusses the role of mitochondrial dysfunction, oxidative stress and mitochondrial drug development. The second and third sections bring light to forensic toxicology and drug poisoning followed by environmental toxicity.

High Density Lipoproteins: From Biological Understanding to Clinical Exploitation

Authors: ---
Book Series: Handbook of Experimental Pharmacology ISSN: 01712004 ISBN: 9783319096643 9783319096650 Year: Volume: 224 Pages: 694 DOI: 10.1007/978-3-319-09665-0 Language: English
Publisher: Springer
Subject: Manufactures --- Electrical and Nuclear Engineering --- Chemical Technology --- Business and Management --- Biotechnology --- Therapeutics --- Medicine (General)
Added to DOAB on : 2015-07-20 15:18:00
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n this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation.The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.

Drug Discovery and Development - From Molecules to Medicine

Authors: ---
ISBN: 9789535121282 9789535142225 Year: Pages: 330 DOI: 10.5772/58659 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 09:47:09

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It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.

Making Medicines in Africa: The Political Economy of Industrializing for Local Health

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ISBN: 9781137571335 9781137546470 Year: Pages: 360 DOI: 10.1057/9781137546470 Language: English
Publisher: Palgrave Macmillan
Subject: Political Science --- Therapeutics
Added to DOAB on : 2015-12-16 18:20:38
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This book is open access under a CC-BY license. The importance of the pharmaceutical industry in Sub-Saharan Africa, its claim to policy priority, is rooted in the vast unmet health needs of the sub-continent. Making Medicines in Africa is a collective endeavour, by a group of contributors with a strong African and more broadly Southern presence, to find ways to link technological development, investment and industrial growth in pharmaceuticals to improve access to essential good quality medicines, as part of moving towards universal access to competent health care in Africa. The authors aim to shift the emphasis in international debate and initiatives towards sustained Africa-based and African-led initiatives to tackle this huge challenge. Without the technological, industrial, intellectual, organisational and research-related capabilities associated with competent pharmaceutical production, and without policies that pull the industrial sectors towards serving local health needs, the African sub-continent cannot generate the resources to tackle its populations' needs and demands.

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