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Brief Interventions for Risky Drinkers

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198870 Year: Pages: 83 DOI: 10.3389/978-2-88919-887-0 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Psychiatry
Added to DOAB on : 2016-01-19 14:05:46
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Alcohol is the sixth leading risk factor for disability and premature death all over the world, and one of the leading causes of premature mortality in western societies; it is a leading risk factor for death in young and middle-age males. Heavy drinking accounts for about two thirds of the burden of disease attributable to alcohol. In the early 1980s, screening and brief interventions (SBI) in primary health care settings were proposed as effective strategies to identify risky drinkers and to help them reduce their drinking. Since then, a growing body of evidence, including several meta-analysis and Cochrane reviews, has shown the efficacy and effectiveness of SBI in primary health settings. However, demonstrating the effectiveness of SBI has not been insufficient to facilitate its general implementation in the routines of primary health care physicians, and in fact the dissemination of SBI has proven to be a difficult business. Qualitative and quantitative research has identified most of the facilitators and barriers for its implementation, and publicly funded research has been earmarked to address the dissemination problems worldwide. Some examples are the World Health Organization Phase III and Phase IV studies on the identification and management of alcohol-related problems in primary care, EU funded projects (PHEPA, AMPHORA, ODHIN, BISTAIRS), the UK SIPS trials and the SBIRT developments sponsored by the Substance Abuse & Mental Health Services Administration (SAMHSA) in the USA. The efficacy and effectiveness of SBI in primary health is now well established, but there are still some questions that remain unsolved: which practitioners should deliver them; what length should they be; is there a need for booster sessions; is there added value of a motivational approach? These questions, together with other relevant aspects of SBI, need ongoing research. In recent years, SBIs have been tested in settings other than primary health care, including hospitals, accident and emergency rooms, criminal justice, colleges and universities, social services and pharmacies. In some of those areas, the evidence is scarce (for example, pharmacies) while in others it is very promising (for example, students and hospitals). New technologies have also offered the possibility of online tools, and, in the last few years, different digital-based applications have been tested successfully as new ways to deliver effective SBIs to larger amounts of people. Brief interventions have also spread to drugs other than alcohol. This book aims to be an update of the state-of-the art of brief advice. It is a compilation of articles published by some of the most relevant researchers in the field in Frontiers in Psychiatry between 2014 and 2016.

Managing the Complexity of Critical Infrastructures: A Modelling and Simulation Approach

Authors: --- --- ---
Book Series: Studies in Systems, Decision and Control ISSN: 2198-4182 ISBN: 9783319510422 9783319510439 Year: Volume: 90 Pages: 299 DOI: 10.1007/978-3-319-51043-9 Language: English
Publisher: Springer
Subject: Business and Management --- General and Civil Engineering --- Materials --- Pharmacy and materia medica --- Manufactures --- Computer Science --- Biotechnology
Added to DOAB on : 2017-03-14 12:45:46
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This book summarizes work being pursued in the context of the CIPRNet (Critical Infrastructure Preparedness and Resilience Research Network) research project, co-funded by the European Union under the Seventh Framework Programme (FP7). The project is intended to provide concrete and on-going support to the Critical Infrastructure Protection (CIP) research communities, enhancing their preparedness for CI-related emergencies, while also providing expertise and technologies for other stakeholders to promote their understanding and mitigation of the consequences of CI disruptions, leading to enhanced resilience. The book collects the tutorial material developed by the authors for several courses on the modelling, simulation and analysis of CIs, representing extensive and integrated CIP expertise. It will help CI stakeholders, CI operators and civil protection authorities understand the complex system of CIs, and help them adapt to these changes and threats in order to be as prepared as possible for mitigating emergencies and crises affecting or arising from CIs.

Infection and Inflammation: Potential Triggers of Sudden Infant Deaths

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889450497 Year: Pages: 94 DOI: 10.3389/978-2-88945-049-7 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Allergy and Immunology
Added to DOAB on : 2018-02-27 16:16:44
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There is a growing body of evidence that infectious agents or their products contribute to events leading to unexpected infant deaths. This issue summarizes the current information on the interactions between genetic background of the infant, environmental and developmental risk factors, and the microbial flora of the infant that could trigger lethal responses to common infections.

Improving Bayesian Reasoning: What Works and Why?

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197453 Year: Pages: 207 DOI: 10.3389/978-2-88919-745-3 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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We confess that the first part of our title is somewhat of a misnomer. Bayesian reasoning is a normative approach to probabilistic belief revision and, as such, it is in need of no improvement. Rather, it is the typical individual whose reasoning and judgments often fall short of the Bayesian ideal who is the focus of improvement. What have we learnt from over a half-century of research and theory on this topic that could explain why people are often non-Bayesian? Can Bayesian reasoning be facilitated, and if so why? These are the questions that motivate this Frontiers in Psychology Research Topic. Bayes' theorem, named after English statistician, philosopher, and Presbyterian minister, Thomas Bayes, offers a method for updating one’s prior probability of an hypothesis H on the basis of new data D such that P(H|D) = P(D|H)P(H)/P(D). The first wave of psychological research, pioneered by Ward Edwards, revealed that people were overly conservative in updating their posterior probabilities (i.e., P(D|H)). A second wave, spearheaded by Daniel Kahneman and Amos Tversky, showed that people often ignored prior probabilities or base rates, where the priors had a frequentist interpretation, and hence were not Bayesians at all. In the 1990s, a third wave of research spurred by Leda Cosmides and John Tooby and by Gerd Gigerenzer and Ulrich Hoffrage showed that people can reason more like a Bayesian if only the information provided takes the form of (non-relativized) natural frequencies. Although Kahneman and Tversky had already noted the advantages of frequency representations, it was the third wave scholars who pushed the prescriptive agenda, arguing that there are feasible and effective methods for improving belief revision. Most scholars now agree that natural frequency representations do facilitate Bayesian reasoning. However, they do not agree on why this is so. The original third wave scholars favor an evolutionary account that posits human brain adaptation to natural frequency processing. But almost as soon as this view was proposed, other scholars challenged it, arguing that such evolutionary assumptions were not needed. The dominant opposing view has been that the benefit of natural frequencies is mainly due to the fact that such representations make the nested set relations perfectly transparent. Thus, people can more easily see what information they need to focus on and how to simply combine it. This Research Topic aims to take stock of where we are at present. Are we in a proto-fourth wave? If so, does it offer a synthesis of recent theoretical disagreements? The second part of the title orients the reader to the two main subtopics: what works and why? In terms of the first subtopic, we seek contributions that advance understanding of how to improve people’s abilities to revise their beliefs and to integrate probabilistic information effectively. The second subtopic centers on explaining why methods that improve non-Bayesian reasoning work as well as they do. In addressing that issue, we welcome both critical analyses of existing theories as well as fresh perspectives. For both subtopics, we welcome the full range of manuscript types.

Dull Disasters? How planning ahead will make a difference

Authors: ---
ISBN: 9780198785576 Year: Pages: 160 DOI: 10.1093/acprof:oso/9780198785576.001.0001 Language: English
Publisher: Oxford University Press Grant: World Bank Group
Subject: Economics --- Social and Public Welfare --- Social Sciences --- History --- Migration
Added to DOAB on : 2016-07-14 11:01:15
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Economic losses from disasters are now reaching an average of US$250–$300 billion a year. In the last 20 years, more than 530,000 people died as a direct result of extreme weather events; millions more were seriously injured. Most of the deaths and serious injuries were in developing countries. Meanwhile, highly infectious diseases will continue to emerge or re-emerge, and natural hazards will not disappear. But these extreme events do not need to turn into large-scale disasters. Better and faster responses are possible. The authors contend that even though there is much generosity in the world to support the responses to and recovery from natural disasters, the current funding model, based on mobilizing financial resources after disasters take place, is flawed and makes responses late, fragmented, unreliable, and poorly targeted, while providing poor incentives for preparedness or risk reduction. The way forward centres around reforming the funding model for disasters, moving towards plans with simple rules for early action and that are locked in before disasters through credible funding strategies—all while resisting the allure of post-disaster discretionary funding and the threat it poses for those seeking to ensure that disasters have a less severe impact.

The Foundation of Precision Medicine: Integration of Electronic Health Records with Nenomics Through Basic, Clinical, and Translational Research

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198726 Year: Pages: 194 DOI: 10.3389/978-2-88919-872-6 Language: English
Publisher: Frontiers Media SA
Subject: Genetics --- Science (General)
Added to DOAB on : 2016-01-19 14:05:46
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This eBook contains the 19 articles that were part of a Special Topic in Frontiers in Genetics entitled “Genetics Research in Electronic Health Records Linked to DNA Biobanks”. The Special Issue was published on-line in 2014-2015 and contained papers representing the diverse research ongoing in the integration of electronic health records (EHR) with genomics through basic, clinical, and translational research. We have divided the eBook into four Chapters. Chapter 1 describes the Electronic Medical Records and Genomics (eMERGE) network and its contri-bution to genomics. It highlights methodological questions related to large data sets such as imputation and population stratification. Chapter 2 describes the results of genetic studies on different diseases for which all the phenotypic information was extracted from the EHR with highly specific ePhenotyping algorithms. Chapter 3 focuses on more complex analyses of the genome including copy number variants (CNV), pleiotropy com-bined with phenome-wide association studies (PheWAS), and epistasis (gene-gene interactions). Chapter 4 discusses the use of genetic data together with EHR-derived clinical data in clinical settings, and how to return genetic results to patients and providers. It also contains a comprehensive review on genetic risk scores. We have included mostly Original Research Articles in the eBook, but also Reviews and Methods papers on the relevant topics of analyzing and integrating genomic data. The release of this eBook is timely, since several countries are launching Precision Medicine initiatives. Precision Medicine is a new concept in patient care taking into account individual variability in genetic, environmental and lifestyle factors, when treating diseases or trying to prevent them from developing. It has become an important focus for biomedical, clinical and translational informatics. The papers presented in this eBook are well positioned to educate the readers about Precision Medicine and to demonstrate the potential study designs, methods, strategies, and applications where this type of research can be performed successfully. The ultimate goal is to improve diagnostics and provide better, more targeted care to the patient.

The Role of Play in Children’s Health and Development

ISBN: 9783038421818 9783038421825 Year: Volume: 1st Pages: 200 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-05-12 11:40:05
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