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Re-Enacting Sensorimotor Experience for Cognition

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451487 Year: Pages: 163 DOI: 10.3389/978-2-88945-148-7 Language: English
Publisher: Frontiers Media SA
Subject: General and Civil Engineering
Added to DOAB on : 2017-08-28 14:01:09
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Mastering the sensorimotor capabilities of our body is a skill that we acquire and refine over time, starting at the prenatal stages of development. This learning process is linked to brain development and is shaped by the rich set of multimodal information experienced while exploring and interacting with the environment. Evidence coming from neuroscience suggests the brain forms and mantains body representations as the main strategy to this mastering. Although it is still not clear how this knowledge is represented in our brain, it is reasonable to think that such internal models of the body undergo a continuous process of adaptation. They need to match growing corporal dimensions during development, as well as temporary changes in the characteristics of the body, such as the transient morphological alterations produced by the usage of tools. In the robotics community there is an increasing interest in reproducing similar mechanisms in artificial agents, mainly motivated by the aim of producing autonomous adaptive systems that can deal with complexity and uncertainty in human environments. Although promising results have been achieved in the context of sensorimotor learning and autonomous generation of body representations, it is still not clear how such low-level representations can be scaled up to more complex motor skills and how they can enable the development of cognitive capabilities. Recent findings from behavioural and brain studies suggests that processes of mental simulations of action-perception loops are likely to be executed in our brain and are dependent on internal motor representations. The capability to simulate sensorimotor experience might represent a key mechanism behind the implementation of further cognitive skills, such as self-detection, self-other distinction and imitation. Empirical investigation on the functioning of similar processes in the brain and on their implementation in artificial agents is fragmented. This e-book comprises a collection of manuscripts published by Frontiers in Robotics and Artificial Intelligence, under the section Humanoid Robotics, on the research topic re-enactment of sensorimotor experience for cognition in artificial agents. This compendium aims at condensing the latest theoretical, review and experimental studies that address new paradigms for learning and integrating multimodal sensorimotor information in artificial agents, re-use of the sensorimotor experience for cognitive development and further construction of more complex strategies and behaviours using these concepts. The authors would like to thank M.A. Dylan Andrade for his art work for the cover.

Structure-Based Drug Design for Diagnosis and Treatment of Neurological Diseases

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451234 Year: Pages: 204 DOI: 10.3389/978-2-88945-123-4 Language: English
Publisher: Frontiers Media SA
Subject: Therapeutics --- Neurology --- Science (General)
Added to DOAB on : 2017-07-06 13:27:36
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European Cooperation in Science and Technology (COST) supports the collaboration of nationally-funded science and technology research through the creation of networks. COST is the longest-running European framework enhancing cooperation among researchers, engineers and scholars across Europe. The COST Action CM1103 “Structure-based drug design for diagnosis and treatment of neurological diseases: dissecting and modulating complex function in the monoaminergic systems of the brain” is a good example of the advances possible through interdisciplinary collaboration on difficult problems. COST Action CM1103 brought together 28 research groups from 18 countries to collaborate for four years on multi-target drug design for complex neuropathologies. The interdisciplinary expertise of the members is spans the range from computational enzymology to human studies, providing outstanding opportunities for the interdisciplinary development of trainees, and is reflected in the articles in this e-book. This Research Topic covers progress in multi-target drug design for the complex neuropathologies of the monoamine system that are apparent, for example, in Alzheimer’s disease. After a mini-review to introduce the topic of multi-target drug design, the other articles review the Research topic from their own perspective, two from computational approaches, three from medicinal chemistry, two from molecular pharmacology, and two from studies in whole brain. This multi-faceted approach describes new compounds, new methodology, and advances in the basic science of understanding the brain. This Ebook is based upon work from COST Action (CM1103 “Structure-based drug design for diagnosis and treatment of neurological diseases: dissecting and modulating complex function in the monoaminergic systems of the brain"), supported by COST (European Cooperation in Science and Technology). COST (European Cooperation in Science and Technology) is a pan-European intergovernmental framework. Its mission is to enable break-through scientific and technological developments leading to new concepts and products and thereby contribute to strengthening Europe’s research and innovation capacities. It allows researchers, engineers and scholars to jointly develop their own ideas and take new initiatives across all fields of science and technology, while promoting multi- and interdisciplinary approaches. COST aims at fostering a better integration of less research intensive countries to the knowledge hubs of the European Research Area. The COST Association, an International not-for-profit Association under Belgian Law, integrates all management, governing and administrative functions necessary for the operation of the framework. The COST Association has currently 36 Member Countries. www.cost.eu

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