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Drug Delivery Technology Development in Canada

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ISBN: 9783039280049 9783039280056 Year: Pages: 352 DOI: 10.3390/books978-3-03928-005-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-01-07 09:21:22
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Abstract

Canada continues to have a rich history of ground-breaking research in drug delivery within academic institutions, pharmaceutical industry and the biotechnology community.

Keywords

doxorubicin --- MG63 --- Vitamin D --- DOX-Vit D --- hypoxia-induced chemoresistance --- cisplatin --- polymeric micelle --- EGFR-targeted therapy --- STAT3 --- HIF-1 --- GE11 peptide --- pharmacological Inhibitors of HIF-1 and STAT3 --- combination therapy --- pharmacokinetics --- antibodies --- radiolabeling --- biodistribution --- mouse models --- oral formulation --- amphotericin B --- fungal infections --- parasitic infections --- developing world --- drug delivery --- liposomes --- drug delivery systems --- innovation --- lipid nanoparticles --- Metaplex --- triggered drug release --- liposomes --- ultrasound --- magnetic fields --- radiation --- oral delivery --- biological barriers --- co-delivery --- throughput --- sustained delivery --- phospholipid complex --- rosmarinic acid --- bioaccessibility --- dissolution --- TNO gastrointestinal model --- gastrointestinal simulator --- phytosterols --- tocopherols --- liposomes --- canola oil deodorizer distillate --- model orange juice --- virus --- plant --- bacteriophage --- phage display --- drug discovery --- encapsulation --- drug delivery --- blood-brain barrier --- intra-arterial chemotherapy --- malignant gliomas --- primary central nervous system lymphomas --- transdermal drug delivery --- Canada --- skin --- permeation enhancers --- oral, head and neck squamous cell carcinoma --- targeted therapies --- drug delivery systems --- nanoparticles --- controlled drug delivery --- circadian clock --- chronotherapy --- precision medicine --- cationic gemini surfactant --- melphalan --- inclusion complex --- ROESY NMR spectroscopy --- 3D spheroid --- drug-resistant melanoma --- liposome --- water miscible solvents --- remote loading --- staurosporine --- cancer --- gambogic acid --- loading gradients --- mefloquine --- child friendly formulation --- blood-brain barrier (BBB) --- drug delivery --- transient modulation --- HAV6 cadherin peptide --- adenanthin --- magnetic resonance imaging (MRI) --- medulloblastoma --- drug delivery --- pharmaceutics --- drug development --- formulation and dosage form development --- translational research --- biologicals --- small molecules --- clinical trials --- pharmacokinetics --- medical devices --- route of administration --- nifedipine --- emulsion --- flavonoids --- topical formulation --- quercetin --- photostabilizers

Flow and Transport Properties of Unconventional Reservoirs 2018

Authors: --- --- ---
ISBN: 9783039211166 9783039211173 Year: Pages: 364 DOI: 10.3390/books978-3-03921-117-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-08-28 11:21:27
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Unconventional reservoirs are usually complex and highly heterogeneous, such as shale, coal, and tight sandstone reservoirs. The strong physical and chemical interactions between fluids and pore surfaces lead to the inapplicability of conventional approaches for characterizing fluid flow in these low-porosity and ultralow-permeability reservoir systems. Therefore, new theories and techniques are urgently needed to characterize petrophysical properties, fluid transport, and their relationships at multiple scales for improving production efficiency from unconventional reservoirs. This book presents fundamental innovations gathered from 21 recent works on novel applications of new techniques and theories in unconventional reservoirs, covering the fields of petrophysical characterization, hydraulic fracturing, fluid transport physics, enhanced oil recovery, and geothermal energy. Clearly, the research covered in this book is helpful to understand and master the latest techniques and theories for unconventional reservoirs, which have important practical significance for the economic and effective development of unconventional oil and gas resources.

Keywords

fracturing fluid --- rheology --- chelating agent --- viscosity --- polymer --- fluid-solid interaction --- velocity profile --- the average flow velocity --- flow resistance --- pore network model --- shale gas --- volume fracturing --- finite volume method --- production simulation --- multi-scale flow --- multi-scale fracture --- shale gas reservoir --- fractured well transient productivity --- succession pseudo-steady state (SPSS) method --- complex fracture network --- multi-scale flow --- analysis of influencing factors --- tight sandstones --- spontaneous imbibition --- remaining oil distributions --- imbibition front --- imbibition recovery --- NMR --- slip length --- large density ratio --- contact angle --- pseudo-potential model --- lattice Boltzmann method --- micro-fracture --- dissolved gas --- experimental evaluation --- reservoir depletion --- recovery factor --- tight oil --- Lucaogou Formation --- tight oil --- pore structure --- prediction by NMR logs --- tight oil reservoir --- SRV-fractured horizontal well --- multiporosity and multiscale --- flow regimes --- productivity contribution degree of multimedium --- equilibrium permeability --- non-equilibrium permeability --- matrix–fracture interaction --- effective stress --- coal deformation --- porous media --- non-linear flow --- conformable derivative --- fractal --- hydraulic fracturing --- tight reservoirs --- fracture diversion --- extended finite element method --- fracture network --- gas adsorption capacity --- shale reservoirs --- influential factors --- integrated methods --- sulfonate gemini surfactant --- thickener --- temperature-resistance --- clean fracturing fluid --- low-salinity water flooding --- clay mineral composition --- enhanced oil recovery --- wetting angle --- pH of formation water --- fractional diffusion --- fractal geometry --- analytical model --- shale gas reservoir --- carbonate reservoir --- petrophysical characterization --- pore types --- pore structure --- permeability --- fractal dimension --- reservoir classifications --- deep circulation groundwater --- groundwater flow --- geothermal water --- faults --- isotopes --- shale permeability --- local effect --- global effect --- matrix-fracture interactions --- nanopore --- pore structure --- shale --- tight sandstone --- mudstone --- nitrogen adsorption --- fractal --- enhanced geothermal system --- well-placement optimization --- fracture continuum method --- 0-1 programming --- unconventional reservoirs --- petrophysical characterization --- fluid transport physics

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MDPI - Multidisciplinary Digital Publishing Institute (2)


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CC by-nc-nd (2)


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english (2)


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2019 (2)