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Pediatric Palliative Care

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ISBN: 9783038973508 / 9783038973515 Year: Pages: 252 DOI: 10.3390/books978-3-03897-351-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Pediatrics --- Medicine (General)
Added to DOAB on : 2019-02-08 09:55:16
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At least 20 million children worldwide would benefit from Pediatric Palliative Care (PPC) annually, and eight million children would need specialized PPC services. In the USA alone, more than 42,000 children, 0–19 years, die annually; fifty-five percent of them are infants younger than one year old. Interdisciplinary PPC is about matching treatment to patient goals and is considered specialized medical care for children with a serious illness. It is focused on relieving pain, distressing symptoms, and stress from a serious illness and is appropriate at any age and at any stage, together with curative treatment. The primary PPC goal is to improve the quality of life both for the child and for his/her family.Sadly, advances in the control of symptoms in children dying of life-limiting diseases have often not kept pace with treatment directed at curing the underlying disease. Data reveal that the majority of distressing symptoms in children with an advanced serious illness (such as pain, dyspnea and nausea/vomiting) are not treated, and, when treated, therapy is commonly ineffective. Emerging evidence shows that palliative care involvement results in improved quality of life, as well as prolongation of life.High-quality pediatric palliative care for children with serious illnesses is now an expected standard of medical care. However, there still remain significant barriers to achieving optimal care, related to lack of formal education, reimbursement issues, the emotional impact of caring for a dying child, and most importantly, the lack of interdisciplinary PPC teams with sufficient staffing.Fortunately, considerable advances have been made in recent years providing PPC around the globe both in resource-poor and resource-rich countries through care provided at children’s hospitals, outpatient palliative care clinics, palliative home care, and free-standing children’s hospice houses. This book, authored by leading authorities in the field, is dedicated to describing existing gaps, as well as the achievements made in clinical care, education, training, and research.

Consideration of Abiotic Natural Resources in Life Cycle Assessments

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ISBN: 9783038975458 / 9783038975465 Year: Pages: 174 DOI: 10.3390/books978-3-03897-546-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Sciences
Added to DOAB on : 2019-01-28 11:06:31
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The book contains a collection of articles dealing with how the extraction of mineral resources can be considered in environmental analyses such as Life Cycle Assessment (LCA). The consumption of resources, e.g., metals, is increasing strongly worldwide. This is associated with more energy use; environmental pollution; and social, economic, and political consequences. An increase is also expected for the coming decades. At the same time, modern products and technologies, even in the field of renewable energies, require a large number of critical raw materials. A crucial question here is the exhaustibility of natural resources. What is the relevance of resource depletion today? Must a geological shortage of metals be expected in the foreseeable future? How could such a thing be considered in the LCA of products and weighed against other environmental aspects? The articles in question have been written over the past three years by leading experts in both geology and environmental sciences and show the breadth of the controversial discussion.

Human Factors in Green Building

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ISBN: 9783038975663 9783038975670 Year: Pages: 200 DOI: 10.3390/books978-3-03897-567-0 Language: Green Building;Post-occupancy Evaluation;Indoor Environment Quality Comfort Health and Wellbeing;Productivity;Job Satisfaction;Quality of Life;Use Behaviour; Healthcare Facilities
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Construction --- Architecture
Added to DOAB on : 2019-01-23 09:42:11
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World Green Building Council suggests that health, well-being and productivity should be the next chapter for green building. There is an obvious shift of green building movement from technology-centric towards human-centric, which culminates in recent WELL Building Standard, focusing exclusively on human health and wellness. This special issue aims to push forward the research, discourse and practice of green building towards more human-oriented design solutions. Particularly, this special issue collects papers on: Post-occupancy evaluation of green buildingsIndoor Environmental Quality (IEQ)Thermal Comfort and Adaptive BehaviorsQuality of Life and HousingHealthcare Design

Environmentally Sustainable Livestock Production

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ISBN: 9783038975526 / 9783038975533 Year: Pages: 290 DOI: 10.3390/books978-3-03897-553-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Sciences --- Social Sciences
Added to DOAB on : 2019-01-25 10:30:03
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This book looks at key research covering a wide range of aspects of environmental sustainability and the mitigation of environmental impacts of livestock production, including emissions of greenhouse gases (carbon dioxide, methane, nitrous oxide), nitrogen and phosphorus excretion, ammonia emissions, land use and land management, and use of energy and other resources. All the globally most important livestock species (beef and dairy cattle, pigs, broiler chicken and laying hens) are covered in the book. The mitigation methods assessed in the papers include general system changes, changes in feeding, improvement of animal health, and new technologies of manure management. The scope of the papers included in this book ranges from farm level mitigation methods to national level system changes. This book also addresses methodological development in assessing the environmental sustainability of the livestock production chains, including holistic methods, such as environmental and social life cycle assessment (LCA) and other modeling approaches.

The Origin and Early Evolution of Life: Prebiotic Chemistry of Biomolecules

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ISBN: 9783039216062 / 9783039216079 Year: Pages: 288 DOI: 10.3390/books978-3-03921-607-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:16
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Studying the origin of life is one of man’s greatest achievements over the last sixty years. The fields of interest encompassed by this quest are multiple and interdisciplinary: chemistry, physics, biology, biochemistry, mathematics, geology but also statistics, atmospheric science, meteorology, oceanography, and astrophysics. Recent scientific discoveries, such as water on Mars and the existence of super-Earths with atmospheres similar to primordial Earth, have pushed researchers to simulate prebiotic conditions in explaining the abiotic formation of molecules essential to life. This collection of articles offers an overview of recent discoveries in the field of prebiotic chemistry of biomolecules, their formation and selection, and the evolution of complex chemical systems.

Keywords

origin of life --- systems chemistry --- Chemomimesis --- Molecular Darwinism --- origin of life --- prebiotic chemistry --- thiol-rich peptides --- cysteine --- aminonitriles --- imidazoles --- origin of life --- prebiotic chemistry --- nucleotide and nucleoside synthesis --- protein design --- novel metalloproteins --- binary patterned amino acid sequences --- prebiotic chemistry --- population growth --- replication --- growth order --- Darwinian evolution --- selection --- origin of life --- abiogenesis --- carbon fixation --- hydrothermal vents --- electrochemistry --- reduction --- digit multiplicity --- information --- transmission --- encoding --- translation --- diversity --- function --- origin of life --- layered double hydroxide (LDH) clay --- pentose diphosphate --- pentopyranose nucleic acid --- arabinopyranose nucleic acid --- RNA --- base pairing --- purine precursor --- inosine --- AICAR --- peptide/RNA world --- prebiotic information system --- translation and the genetic code --- bridge peptide and aaRS --- ribozyme and tRNA --- tRNA and mRNA --- coevolution of translation machine and the genetic code --- MVC architecture pattern and biological information --- numerical codons --- AnyLogic software for computer simulation of translation machine --- phosphoryl transfer --- metabolism --- energy currency --- mixed anhydride --- origin of life --- hypercycle --- Monte Carlo --- prebiotic chemistry --- carbamic acid --- carbon dioxide-ammonia ices --- infrared spectra --- anharmonicity --- origin of life --- metabolism --- phosphates --- network expansion simulation --- thermodynamic bottleneck --- molecular clocks --- ab initio molecular dynamics --- catalysis --- prebiotic soup --- origins of life --- aldol reaction --- mechanochemistry --- minerals --- monosaccharides --- prebiotic chemistry --- prebiotic polymerization --- nucleotide oligomerization --- abasic oligomers --- nucleotide stability --- stability as a selection pressure --- dry-wet cycles --- genetic code origin --- tRNA accretion model --- tRNA-synthetase --- metabolism --- thioester --- nucleotidyltransferases --- early peptides --- ribosome --- n/a

There is a Crack in Everything—Education and Religion in a Secular Age

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ISBN: 9783039212774 / 9783039212781 Year: Pages: 266 DOI: 10.3390/books978-3-03921-278-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-12-09 16:39:37
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There are two constants in academic and theological discourse throughout history, they are the debate around secularization and the dialogue concerning the intersection of religion and education. Each age has had its debate about modernizing forces that drive concerns of impending secularization. In this publication this theme is approached from perspectives of teachers, of students, of policy makers and situated in a politico-historical context. Aware of the fact that in today’s plural societies one sacred canopy is non-existent anymore, cracks of the sacred canopy/canopies are described, as well as ‘the light that gets in’, the possible and challenging ways out are roughly sketched. We expect that each of the contributions of scholars of the East and the West, of the North and the South, and their presented examples and case studies, will stimulate the ongoing exploration and elaboration on the relationship between education and religion in todays’ and the coming world – work-in-progress for coming generations.

Keywords

religious education --- secularization --- pluralism --- non-confessional --- classroom observation --- ethnography --- Christian --- university --- radicalization --- post-secular --- secular --- religion education --- secularity --- secularism --- religion in public life --- representation of religion --- Bible --- Qur’an --- Ubuntu --- orthodoxy --- orthokardia --- orthopraxis --- Weltanschauung --- inter-worldview education --- Europe --- tolerance --- inequality --- power --- state Jewish religious education --- state Jewish secular education --- state Arab Moslem education --- state Christian education --- state Druze education --- religious and heritage education --- citizenship education --- religious minorities --- secularism --- Muslim --- youth --- immigration --- social boundaries --- identification --- college --- Québec --- inclusion --- worldview education --- universal design for learning --- learning in the presence of the other --- reflexive inclusion --- secularization --- rationality --- medicine --- theology --- symbiotic relevance --- school identity --- secularization --- secondary education --- teachers --- worldviews --- morality --- spirituality --- religion --- religious education --- life-as --- subjective-life --- secularism --- religious education --- values education --- strong religious schools --- Dutch Bible Belt --- citizenship education --- religious education --- liberal society --- secularization --- symbolic language --- philosophy of life --- religious sources of meaning --- metaphoric sensitivity --- inventive imagination --- role playing/bibliodrama --- identity construction --- life orientation --- bibliodrama --- narratives --- interreligious encounters --- education --- image of imams --- secularization --- plurality --- spiritual religiosity --- popular religiosity --- radicalization --- n/a --- n/a

Measures of Spirituality/Religiosity—Description of Concepts and Validation of Instruments

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ISBN: 9783038977582 9783038977599 Year: Pages: 148 DOI: 10.3390/books978-3-03897-759-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-04-25 16:37:17
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Why do we need more questionnaires to measure aspects of spirituality/religiosity when we already have so many well-tried instruments in use? One answer is that research in this field is growing and that new research questions continuously do arise. Several of these new questions cannot be easily answered with the instruments designed for previous questions. The field is expanding and, consequently, the research topics. Meanwhile several multidimensional instruments were developed which cover existential, prosocial, religious and non-religious forms of spirituality, hope, peace and trust&mdash;and several more. The &lsquo;disadvantage&rsquo; of these instruments is the fact that some are conceptually broad and often rather unspecific, but they might be suited quite well for culturally and spiritually diverse populations when the intention is to compare such diverse groups. This is the reason why more research on new instruments is needed as can be found in this Special Issue, and to stimulate a critical debate about their pros and cons.

Possible Scenarios for Homochirality on Earth

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ISBN: 9783039217229 / 9783039217236 Year: Pages: 318 DOI: 10.3390/books978-3-03921-723-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General)
Added to DOAB on : 2019-12-09 11:49:16
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In 1978, Fred Hoyle proposed that interstellar comets carrying several viruses landed on Earth as part of the panspermia hypotheses. With respect to life, the origin of homochirality on Earth has been the greatest mystery because life cannot exist without molecular asymmetry. Many scientists have proposed several possible hypotheses to answer this long-standing L-D question. Previously, Martin Gardner raised the question about mirror symmetry and broken mirror symmetry in terms of the homochirality question in his monographs (1964 and 1990). Possible scenarios for the L-D issue can be categorized into (i) Earth and exoterrestrial origins, (ii) by-chance and necessity mechanisms, and (iii) mirror-symmetrical and non-mirror-symmetrical forces as physical and chemical origins. These scenarios should involve further great amplification mechanisms, enabling a pure L- or D-world.

Keywords

chirogenesis --- enantiomorphism --- nepheline --- magmatic flow --- etch figures --- origin of life --- biological homochirality --- deracemization --- super-high-velocity impact --- plasma reactor --- absolute asymmetric synthesis --- amino acids --- origin of life --- amino acid handedness --- nucleus–molecular coupling --- chirality --- circularly polarized luminescence --- circular dichroism --- symmetry breaking --- parity violation --- weak neutral current --- tunneling --- Z0 boson --- homochirality --- precision measurement --- homochirality --- circularly polarized light --- asymmetric reaction --- polymer --- ?-strand --- hidden chirality --- two-fold helix --- multi-point approximation --- tilt-chirality --- high dimensional chirality --- spin polarized electrons --- homochirality --- magnetism --- prebiotic --- environmental chirality --- C1- and C2-symmetric catalysts --- chiral field (memory) --- racemic field --- Viedma ripening effect --- Wallach’s rule --- heat capacity --- metal-organic framework --- triethylenediamine (DABCO) molecules --- racemate --- Salam hypothesis --- homochirality --- parity violation --- neutrinos --- gravitation --- enantiomer self-disproportionation --- SDE --- achiral stationary phase --- homochiral and heterochiral aggregates --- chiral separation --- chirality --- genesis of life chirality --- asymmetric autocatalysis --- homochirality --- chirality --- asymmetric synthesis --- Soai reaction --- biological homochirality --- enantioselective reaction --- autocatalysis --- origin of life --- replicators --- bioorganic homochirality --- circularly polarized photon --- spin-polarized lepton --- parity violation in the weak interaction --- symmetry breaking --- assemblies --- supramolecular chirality --- homochirality --- self-assembly --- vortex --- lipid --- supramolecular assembly --- symmetry breaking --- homochirality

Long-Term Health Effects of the 9/11 Disaster

Authors: --- ---
ISBN: 9783039218127 / 9783039218134 Year: Pages: 298 DOI: 10.3390/books978-3-03921-813-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Philosophy
Added to DOAB on : 2019-12-09 11:49:16
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The terrorist attacks on the World Trade Center towers on September 11, 2001, also referred as 9/11, was an iconic event in US history that altered the global and political response to terrorism. The attacks, which involved two planes hitting the twin towers in Lower Manhattan, New York City, resulted in the collapse of the buildings and over 2800 deaths of occupants of the buildings, fire, police and other responders and persons on the street in the vicinity of the collapsing buildings. The destroyed towers and the surrounding buildings have since been replaced but the health effects that resulted from the release of tons of dust, gases and debris as well as the life threat trauma are ongoing, and represent a major health burden among persons directly exposed. Hundreds of scientific publications have documented the physical and mental health effects attributed to the disaster. The current state-of-the-art in understanding the ongoing interactions of physical and mental health, especially PTSD, and the unique mechanisms by which pollutants from the building collapse, have resulted in long term pulmonary dysfunction, course of previously reported conditions, potential emerging conditions (e.g., heart disease and autoimmune diseases), as well as quality of life, functioning and unmet health care needs would be in the purview of this Special Issue on the 9/11 Disaster.

Keywords

counseling --- post-disaster --- psychotherapy --- mental health treatment --- treatment utilization --- World Trade Center --- indoor allergens sensitization --- asthma quality of life --- asthma control --- asthma outcomes --- mini asthma quality of life questionnaire --- asthma morbidity --- WTC-related asthma --- immunoglobulin E --- allergen exposure --- WTC attack --- respiratory symptoms --- lower Manhattan residents --- cleaning practices --- WTC --- fibrotic sarcoid --- injury --- inflammation --- fibrosis --- World Trade Center disaster --- pulmonary fibrosis --- dust --- injury --- physical health --- mental health --- World Trade Center disaster --- Short Form-12 (SF-12) --- HQoL --- 9/11 --- 9/11 disaster --- handgrip strength --- WTC responders --- PTSD --- depression --- aging --- 9/11 impact --- retirement --- chronic disease --- PTSD --- disaster --- income loss --- PTSD symptom change --- PCL score --- longitudinal analysis --- PTSD cluster --- WTC survivors --- 9/11 disaster --- obstructive sleep apnea --- comorbid insomnia --- sleep-related quality of life --- chronic sinusitis --- sleepiness --- WTC responders --- thyroid cancer --- 9/11 disaster --- World Trade Center --- surveillance bias --- sarcoidosis --- World Trade Center (WTC) --- Scadding stage --- lung function --- severe lung disease --- extrathoracic sarcoidosis --- cardiac sarcoidosis --- unmet mental health care needs --- Asian Americans --- World Trade Center attack --- disaster --- mental health conditions --- mental health service use --- health insurance --- social support --- stressful life events --- cognitive reserve --- cognitive decline --- latent class analysis --- disaster epidemiology --- PTSD --- airway physiology --- dust --- environmental health --- forced oscillation --- respiratory function --- small airway disease --- paresthesia --- neuropathic symptoms --- Cox regression --- hazard function --- World Trade Center exposure --- metabolic syndrome --- airway hyperreactivity --- World Trade Center --- disaster mental health --- evidence-based treatment --- mental health service utilization --- quality improvement --- 9/11 --- screening --- thyroid cancer --- biomarkers --- medical imaging --- pulmonary function tests --- lung injury --- occupational exposure --- epidemiological studies --- peripheral neuropathy --- prevalence --- World Trade Center --- rescue/recovery workers --- occupational exposure --- sarcoidosis --- World Trade Center --- 9/11 --- genetics --- firefighters --- FDNY --- 9/11 disaster --- asthma --- trigger(s) --- air pollution --- irritant(s) --- health-related quality of life --- n/a

New Research in Obsessive-Compulsive Disorder and Major Depression

Authors: ---
ISBN: 9783039210909 / 9783039210916 Year: Pages: 102 DOI: 10.3390/books978-3-03921-091-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Psychology
Added to DOAB on : 2019-06-26 08:44:07
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Major depression and obsessive–compulsive disorder (OCD) are now recognized among the most frequent psychiatric disorders, affecting 16–17% and 2–3% of the general population, respectively. They are commonly characterized by: i) a high level of psychiatric and somatic comorbidities; ii) a recurrence or chronic profile; and iii) a negative impact on daily functions, thereby leading to a profound impairment of quality of life. Despite significant advances in pharmacological and psychological therapies over the last decades, unsuccessful responses to standard treatment strategies are classically observed in approximately 20–30% of cases. Therefore, there is a significant need for improving the pathophysiological knowledge through a better identification of environmental, clinical, psychological, genetic, anatomical, and biological determinants, specifically implied in the development, the phenotypic expression, and the relapsing course and/or contributing to the therapeutic failure in major depression and OCD. We are convinced that this research approach is particularly relevant providing critical support for the promotion of innovative treatment alternatives potentially useful for the management of resistant forms of major depression and OCD.

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