Search results: Found 66

Listing 1 - 10 of 66 << page
of 7
>>
Sort by
Statistical Population Genomics

Author:
Book Series: Methods in Molecular Biology ISBN: 9781071601990 Year: Pages: 468 DOI: 10.1007/978-1-0716-0199-0 Language: English
Publisher: Springer Nature
Subject: Biology
Added to DOAB on : 2020-01-29 11:21:12
License:

Loading...
Export citation

Choose an application

Abstract

This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions.

Pre-Field Screening Protocols for Heat-Tolerant Mutants in Rice

Authors: --- --- --- --- et al.
ISBN: 9783319773384 Year: Pages: 39 DOI: 10.1007/978-3-319-77338-4 Language: English
Publisher: Springer Nature
Subject: Botany --- Agriculture (General)
Added to DOAB on : 2020-02-04 11:21:03
License:

Loading...
Export citation

Choose an application

Abstract

This open access book presents simple, robust pre-field screening protocols that allow plant breeders to screen for enhanced tolerance to heat stress in rice. Two critical heat-sensitive stages in the lifecycle of the rice crop are targeted – the seedling and flowering stages – with screening based on simple phenotypic responses. The protocols are based on the use of a hydroponics system and/or pot experiments in a glasshouse in combination with a controlled growth chamber where the heat stress treatment is applied. The protocols are designed to be effective, simple, reproducible and user-friendly. The protocols will enable plant breeders to effectively reduce the number of plants from a few thousands to less than 100 candidate individual mutants or lines in a greenhouse/growth chamber, which can then be used for further testing and validation in the field conditions. The methods can also be used to classify rice genotypes according to their heat tolerance characteristics. Thus, different types of heat stress tolerance mechanisms can be identified, presenting opportunities for pyramiding different (mutant) sources of heat stress tolerance.

Evolutionary Genomics

Author:
Book Series: Methods in Molecular Biology ISBN: 9781493990740 Year: Pages: 780 DOI: 10.1007/978-1-4939-9074-0 Language: English
Publisher: Springer Nature
Subject: Biology
Added to DOAB on : 2020-01-29 11:21:11
License:

Loading...
Export citation

Choose an application

Abstract

This open access book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results. Authoritative and comprehensive, Evolutionary Genomics: Statistical and Computational Methods, Second Edition aims to serve both novices in biology with strong statistics and computational skills, and molecular biologists with a good grasp of standard mathematical concepts, in moving this important field of study forward.

Linear Selection Indices in Modern Plant Breeding

Authors: ---
ISBN: 9783319912233 Year: Pages: 256 DOI: 10.1007/978-3-319-91223-3 Language: English
Publisher: Springer Nature
Subject: Biology --- Botany --- Zoology
Added to DOAB on : 2020-02-05 11:21:15
License:

Loading...
Export citation

Choose an application

Abstract

This open access book focuses on the linear selection index (LSI) theory and its statistical properties. It addresses the single-stage LSI theory by assuming that economic weights are fixed and known - or fixed, but unknown - to predict the net genetic merit in the phenotypic, marker and genomic context. Further, it shows how to combine the LSI theory with the independent culling method to develop the multistage selection index theory. The final two chapters present simulation results and SAS and R codes, respectively, to estimate the parameters and make selections using some of the LSIs described. It is essential reading for plant quantitative geneticists, but is also a valuable resource for animal breeders.

Bird Species

Author:
Book Series: Fascinating Life Sciences ISBN: 9783319916897 Year: Pages: 266 DOI: 10.1007/978-3-319-91689-7 Language: English
Publisher: Springer Nature
Subject: Biology --- Zoology
Added to DOAB on : 2020-02-05 11:21:16
License:

Loading...
Export citation

Choose an application

Abstract

The average person can name more bird species than they think, but do we really know what a bird “species” is? This open access book takes up several fascinating aspects of bird life to elucidate this basic concept in biology. From genetic and physiological basics to the phenomena of bird song and bird migration, it analyzes various interactions of birds – with their environment and other birds. Lastly, it shows imminent threats to birds in the Anthropocene, the era of global human impact. Although it seemed to be easy to define bird species, the advent of modern methods has challenged species definition and led to a multidisciplinary approach to classifying birds. One outstanding new toolbox comes with the more and more reasonably priced acquisition of whole-genome sequences that allow causative analyses of how bird species diversify. Speciation has reached a final stage when daughter species are reproductively isolated, but this stage is not easily detectable from the phenotype we observe. Culturally transmitted traits such as bird song seem to speed up speciation processes, while another behavioral trait, migration, helps birds to find food resources, and also coincides with higher chances of reaching new, inhabitable areas. In general, distribution is a major key to understanding speciation in birds. Examples of ecological speciation can be found in birds, and the constant interaction of birds with their biotic environment also contributes to evolutionary changes. In the Anthropocene, birds are confronted with rapid changes that are highly threatening for some species. Climate change forces birds to move their ranges, but may also disrupt well-established interactions between climate, vegetation, and food sources. This book brings together various disciplines involved in observing bird species come into existence, modify, and vanish. It is a rich resource for bird enthusiasts who want to understand various processes at the cutting edge of current research in more detail. At the same time it offers students the opportunity to see primarily unconnected, but booming big-data approaches such as genomics and biogeography meet in a topic of broad interest. Lastly, the book enables conservationists to better understand the uncertainties surrounding “species” as entities of protection.

Designing Sustainable Technologies, Products and Policies

Authors: --- ---
ISBN: 9783319669809 9783319669816 Year: Volume: 1 Pages: 520 DOI: https://doi.org/10.1007/978-3-319-66981-6 Language: English
Publisher: Springer Nature
Subject: Environmental Engineering
Added to DOAB on : 2019-09-10 16:32:12
License:

Loading...
Export citation

Choose an application

Abstract

This open access book provides insight into the implementation of Life Cycle approaches along the entire business value chain, supporting environmental, social and economic sustainability related to the development of industrial technologies, products, services and policies; and the development and management of smart agricultural systems, smart mobility systems, urban infrastructures and energy for the built environment. The book is based on papers presented at the 8th International Life Cycle Management Conference that took place from September 3-6, 2017 in Luxembourg, and which was organized by the Luxembourg Institute of Science and Technology (LIST) and the University of Luxembourg in the framework of the LCM Conference Series.

Programming the HPA-axis by early life experience: Mechanisms of stress susceptibility and adaptation

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889194810 Year: Pages: 140 DOI: 10.3389/978-2-88919-481-0 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology --- Medicine (General) --- Internal medicine
Added to DOAB on : 2015-11-16 15:44:59
License:

Loading...
Export citation

Choose an application

Abstract

Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.

Applied Olfactory Cognition

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193431 Year: Pages: 239 DOI: 10.3389/978-2-88919-343-1 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2016-03-10 08:14:32
License:

Loading...
Export citation

Choose an application

Abstract

Foreword by Richard J. Stevenson, Macquarie University (Australia):It was long thought that the human nose might be able to discriminate somewhere in the order of 10,000 different odourants. The recent finding that the human nose can discriminate something like a trillion different smells serves as yet another reminder that we have again underestimated the capacity of our sense of smell (Bushdid, Magnasco, Vosshall & Keller, 2014). This volume serves as a further corrective for anyone who should hold the view that olfaction is unimportant in human affairs. The papers presented in this ebook, carefully collated and overseen by Aldo Zucco, Benoist Schaal, Mats Olsson and Ilona Croy, showcase a large number of quite different reasons for studying the applied side of olfaction, and indeed human olfaction in general. The 23 contributions presented here cover a broad range of topics, which illustrate contemporary interests in our field. Although with a strong applied focus, a noteworthy feature of this ebook is the richness of the theoretical perspectives that are developed. These range from considerations of olfactory perception, memory, expertise, and priming right the way through to receptor genetics. These contributions, from many leading experts in the field, will surely shape much of the applied work linking olfaction to disease, which is a further focus of this ebook. In respect to health and disease, the chapters on aging, pregnancy, depression, alcohol dependency and environmental odours, present overviews and rich new data on many contemporary problems, to which the study of olfaction is now contributing. A particularly notable aspect of olfactory experience is the affective impact that odours can have on people and their lives. The ebook covers some particularly intriguing aspects of work in this area, with empirical studies investigating dissociations between wanting and liking, stress reduction in the elderly, mother-infant bonding, and the emotions that different odourants can evoke. This affective line of work is nicely complemented by empirical studies on expertise, the effect of odours on visual attention, and the relationship between particular personality traits and interest in olfaction. The gradual appropriation of methods from cognitive neuroscience into olfaction is also nicely represented in this ebook, with at least three of the chapters reporting data using neuroimaging, including a particular intriguing study looking at recognition of odours in mixtures. Finally, the close links between olfactory perception and sensory evaluation are also reflected in a chapter on wine. I hope that readers of this e-book will be struck, as I have been in reading its various chapters, how much olfaction affects our lives, and how the study of this sense can enrich it.

Molecular mechanisms for reprogramming hippocampal development and function by early-life stress

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198061 Year: Pages: 100 DOI: 10.3389/978-2-88919-806-1 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
License:

Loading...
Export citation

Choose an application

Abstract

The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in life have profound and persistent effects on hippocampal function and behavior. This research topic focuses on the acute and lasting effects of early-life stress on various developmental processes in the hippocampus, and aims to uncover the molecules that are responsible for early-life stress-programmed effects and underlie resilience or vulnerability to stress-related neuropsychiatric disorders later in life. We hope the articles in this research topic will provide novel insights and stimulate future studies on the mechanisms of early-life stress and brain development.

When (and How) Is Theory of Mind Useful? Evidence from Life-Span Research

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451012 Year: Pages: 182 DOI: 10.3389/978-2-88945-101-2 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2017-07-06 13:27:36
License:

Loading...
Export citation

Choose an application

Abstract

Theory of Mind (ToM) or mentalization is the ability to understand and foresee the behavior referring to one’s own and others’ mental states (Premack & Woodruff, 1978; Wimmer & Perner, 1983). This capacity, which is considered the most representative mechanism of social cognition, is a multifaceted set of competences liable to influence – and be influenced by – a manifold of psychosocial aspects. Studies on typical and atypical/clinical development during life showed that ToM is frequently delayed (e.g. in deafness) or impaired in many clinical conditions (e.g. Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Schizophrenia, Borderline Personality Disorder, Parkinson’s Disease, Alzheimer’s Disease) and, on the other hand, may not be unequivocally a positive experience. It is therefore possible to consider the existence of multiple kinds of Theory of Mind. In fact, ToM may vary along a quantitative and a qualitative continuum. As for the quantitative dimension, the continuum is constituted by the fluctuation between high and low levels of ToM ability in different clinical conditions. Along this continuum, impairment can mean “not enough” ToM (for example in Autism Spectrum Disorder) as well as “too much” ToM (for example in Schizophrenia and Borderline Personality Disorder). The qualitative dimension – highly interrelated with the quantitative one - regards the shift between adaptive (e.g. prosocial, nice ToM) vs. unadaptive (e.g. antisocial, nasty ToM) mental states content. The issue is discussed in light of recent evidence from outstanding researchers working on typical and atypical/clinical populations along the life-span. Findings from the fields of psychology, neuropsychology and neuroscience enrich the research topic argumentation.

Keywords

Theory of Mind --- typical --- clinical --- neural --- life-span

Listing 1 - 10 of 66 << page
of 7
>>
Sort by
Narrow your search