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Participatory reading in late-medieval England

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Book Series: Manchester Medieval Literature and Culture ISBN: 9781526117991 9781526118004 Year: Language: English
Publisher: Manchester University Press Grant: Knowledge Unlatched - 100908
Subject: Languages and Literatures
Added to DOAB on : 2018-04-20 11:02:36
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This book explores how modern media practices can illuminate participatory reading in England from the late-fourteenth to the early-sixteenth centuries. Nonlinear apprehension, immersion and embodiment are practices intimately familiar to readers of Wikipedia, players of video games and users of multi-touch mobile devices. But far from being unique to digital media, they have clear analogues in the pre-modern era. Participatory reading in late-medieval England traces how the affinities between old and new media can reveal fresh insights not only about the digital, but also about the long history of media forms and practices. It thus casts new light on the literary practices of a period pre- and post-print to demonstrate how participatory reading vitally contributed to and shaped these negotiations of fragile authority.

Marine Hydrodynamics

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ISBN: 9780262344999 9780262534826 Year: Pages: 448 Language: English
Publisher: The MIT Press
Subject: Agriculture (General)
Added to DOAB on : 2019-01-17 11:41:31
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A textbook that offers a unified treatment of the applications of hydrodynamics to marine problems.The applications of hydrodynamics to naval architecture and marine engineering expanded dramatically in the 1960s and 1970s. This classic textbook, originally published in 1977, filled the need for a single volume on the applications of hydrodynamics to marine problems. The book is solidly based on fundamentals, but it also guides the student to an understanding of engineering applications through its consideration of realistic configurations. The book takes a balanced approach between theory and empirics, providing the necessary theoretical background for an intelligent evaluation and application of empirical procedures. It also serves as an introduction to more specialized research methods. It unifies the seemingly diverse problems of marine hydrodynamics by examining them not as separate problems but as related applications of the general field of hydrodynamics. The book evolved from a first-year graduate course in MIT's Department of Ocean Engineering. A knowledge of advanced calculus is assumed. Students will find a previous introductory course in fluid dynamics helpful, but the book presents the necessary fundamentals in a self-contained manner. The 40th anniversary of this pioneering book offers a foreword by John Grue.Contents Model Testing • The Motion of a Viscous Fluid • The Motion of an Ideal Fluid • Lifting Surfaces • Waves and Wave Effects • Hydrodynamics of Slender Bodies

Reforms, Organizational Change and Performance in Higher Education

Authors: --- --- ---
ISBN: 9783030117382 Year: Pages: 326 DOI: 10.1007/978-3-030-11738-2 Language: English
Publisher: Springer Nature
Subject: Political Science --- Education
Added to DOAB on : 2020-02-05 11:21:10
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This open access book investigates the effects of changes in leadership and managerial structures of Nordic universities resulting from reforms in the last decade. It builds on a rich, comparative dataset across a multiplicity of system-wide (macro) and organisational (meso and micro) dimensions, namely: reform or policy initiatives; drivers, aims, instruments and actors; structural changes within universities; strategic and performance management; the rise of accountability regimes; incentive and evaluative systems; and perceived changes/effects by the key actors involved, at various levels. The volume provides critical insights to the larger phenomenon of change and adaptation within the public sector. Its findings and implications are of relevance to social science researchers, policy makers, managers/administrators, and external stakeholders.

Mitochondria: Hubs of Cellular Signaling, Energetics and Redox Balance

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889452392 Year: Pages: 228 DOI: 10.3389/978-2-88945-239-2 Language: English
Publisher: Frontiers Media SA
Subject: Physiology --- Science (General)
Added to DOAB on : 2017-10-13 14:57:01
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Poised at the convergence of most catabolic and anabolic pathways, mitochondria are the center of heterotrophic aerobic life, representing a hub in the overall metabolic network of cells. The energetic functions performed by mitochondria face the unavoidable redox hurdle of handling huge amounts of oxygen while keeping its own as well as the cellular redox environment under control. Reactive oxygen species (ROS) are produced in the respiratory chain as a result of the energy supplying function of mitochondria. Originally considered an unavoidable by-product of oxidative phosphorylation, ROS have become crucial signaling molecules when their levels are kept within physiological range. This occurs when their production and scavenging are balanced within mitochondria and cells. Mitochondria-generated hydrogen peroxide can act as a signaling molecule within mitochondria or in the cytoplasm, affecting multiple networks that control, for example, cell cycle, stress response, cell migration and adhesion, energy metabolism, redox balance, cell contraction, and ion channels. However, under pathophysiological conditions, excessive ROS levels can happen due to either overproduction, overwhelming of antioxidant defenses, or both. Under oxidative stress, detrimental effects of ROS include oxidation of protein, lipids, and nucleic acids; mitochondrial depolarization and calcium overload; and cell-wide oscillations mediated by ROS-induced ROS release mechanisms. Mitochondrial dysfunction is central in the pathogenesis of numerous human maladies including cardiomyopathies and neurodegeneration. Diseases characterized by altered nutrient metabolism, such as diabetes and cancer, exhibit elevated ROS levels. These may contribute to pathogenesis by increasing DNA mutation, affecting regulatory signaling and transcription, and promoting inflammation. Under metabolic stress, several ionic channels present in the inner and outer mitochondrial membranes can have pro-life and -death effects. In the present E-book, based on the Frontiers Research Topic entitled: "Mitochondria: Hubs of cellular signaling, energetics and redox balance", we address one of the fundamental questions that the field of ROS biology faces today: how do mitochondria accomplish a reliable energy provision and at the same time keep ROS levels within physiological, non-harming, limits but crucial for cellular signaling function? Additionally, and within the perspective of mitochondria as signaling-energetic hubs in the extensive cellular metabolic network, we ask how can their collective dynamics scale from the subcellular to the cellular, tissue and organ levels to affect function in health and disease.

Disabled Bodies in Early Modern Spanish Literature

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Book Series: Representations: Health, Disability, Culture and Society ISBN: 9781786940780 9781786948441 Year: Language: English
Publisher: Liverpool University Press Grant: Knowledge Unlatched - 102602
Subject: Languages and Literatures
Added to DOAB on : 2019-01-23 06:28:26
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Disabled Bodies in Early Modern Spanish Literature examines the concepts and role of women in selected Spanish discourses and literary texts from the late fifteenth to seventeenth centuries from the perspective of feminist disability theories. It explores a wide range of Spanish medical, regulatory and moral discourses, illustrating how such texts inherit, reproduce and propagate an amalgam of Western traditional concepts of female embodiment. It goes on to examine concrete representations of deviant female characters, focusing on the figures of syphilitic prostitutes and physically decayed aged women in literary texts such as Celestina, Lozana andaluza and selected works by Cervantes and Quevedo. Finally, an analysis of the personal testimony of Teresa de Avila, a nun suffering neurological disorders, complements the discussion of early modern women’s disability.

Women’s Lived Landscapes of War and Liberation in Mozambique

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ISBN: 9780367252472 Year: Pages: 278 Language: English
Publisher: Taylor & Francis
Subject: History
Added to DOAB on : 2020-02-06 11:21:03
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This book tells the history of the changing gendered landscapes of northern Mozambique from the perspective of women who fought in the armed struggle for national independence, diverting from the often-told narrative of women in nationalist wars that emphasizes a linear plot of liberation. Taking a novel approach in focusing on the body, senses, and landscape, Jonna Katto, through a study of the women ex-combatants’ lived landscapes, shows how their life trajectories unfold as nonlinear spatial histories. This brings into focus the women’s shifting and multilayered negotiations for personal space and belonging. This book explores the life memories of the now aging female ex-combatants in the province of Niassa in northern Mozambique, looking at how the female ex-combatants’ experiences of living in these northern landscapes have shaped their sense of socio-spatial belonging and attachment. It builds on the premise that individual embodied memory cannot be separated from social memory; personal lives are culturally shaped. Thus, the book does not only tell the history of a small and rather unique group of women but also speaks about wider cultural histories of body-landscape relations in northern Mozambique and especially changes in those relations. Enriching our understanding of the gendered history of the liberation struggle in Mozambique and informing broader discussions on gender and nationalism, this book will be of interest to students and scholars of African history, especially the colonial and postcolonial history of Lusophone Africa, as well as gender/women’s history and peace and conflict studies.

Vulnerability in Scandinavian Art and Culture

Authors: --- ---
ISBN: 9783030373825 Year: Pages: 324 DOI: 10.1007/978-3-030-37382-5 Language: English
Publisher: Springer Nature
Subject: Media and communication --- Arts in general --- Linguistics --- Languages and Literatures
Added to DOAB on : 2020-05-14 09:27:49
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In this open access book, seventeen scholars discuss how contemporary Scandinavian art and media have become important arenas to articulate and stage various forms of vulnerability in the Scandinavian welfare states. How do discourses of privilege and vulnerability coexist and interact in Scandinavia? How do the Scandinavian countries respond to vulnerability given increased migration? How is vulnerability distributed in terms of margin and centre, normality and deviance? And how can vulnerability be used to move audiences towards each other and accomplish change? We address these questions in an interdisciplinary study that brings examples from celebrated and provocative fiction and documentary films, TV-series, reality TV, art installations, design, literature, graphic art, radio podcasts and campaigns on social media.

Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday

Authors: ---
ISBN: 9783038974161 9783038974178 Year: Pages: 256 DOI: 10.3390/books978-3-03897-417-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Biochemistry
Added to DOAB on : 2019-06-26 08:44:06
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Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.

Keywords

Zingiber officinale --- gingerols --- cytotoxic activity --- oleanolic acid --- high-fat high-carbohydrate diet --- pre-diabetes --- glucose homeostasis --- insulin resistance --- atherosclerosis --- ROS --- HUVECs --- LOX-1 --- alkaloid --- granatane --- N-methylcadaverine --- N-methylpiperidine. reductive deamination --- Mucorales --- Rhizopus arrhizus --- sterol pattern --- antifungal effectivity --- gas chromatography-mass spectrometry (GC-MS) --- posaconazole --- sterol biosynthesis --- sterol 14?-demethylase --- sterol C24-methyltransferase --- mechanism-based inactivators --- antifungals --- azoles --- antiparasitic drugs --- human African trypanosomiasis --- Chagas disease --- synthesis --- squalene cyclase --- cycloartenol synthase --- triterpene --- fern --- Polystichum --- terpene --- isoprenoid --- divalent metal co-factor ligation --- antioxidant --- cholesterol --- degeneration --- oxysterol --- retina --- Smith-Lemli-Opitz syndrome --- algal sterols --- ergosterol biosynthesis --- infectious disease --- lipidomics --- oxyphytosterol --- pharmacognosy --- phytosterol --- sterolomics --- lupeol --- keratinocytes --- fibroblasts --- wound healing --- cell migration --- UV-radiation --- ZnO --- toxicity --- sterol content --- cholesterol --- leishmania --- solanaceae --- withanolides --- aurelianolides --- phytosterols --- mesocarp --- oilseed --- maturity --- pod-blast --- ?-tocopherol --- oil bodies --- campesterol --- stigmasterol --- ?-sitosterol --- sterol --- C4-demethylation complex (C4DMC) --- 4-methylsterol --- hormone --- steroid --- development --- genetic disease --- bile alcohol --- cholestanoic acid --- oxysterol --- sterolomics --- enzyme-assisted derivatization --- electrospray ionization-mass spectrometry --- Girard reagent --- n/a

Children on the Move: The Health of Refugee, Immigrant and Displaced Children

Author:
ISBN: 9783039282005 9783039282012 Year: Pages: 142 DOI: 10.3390/books978-3-03928-201-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: History --- Migration --- Sociology --- Social Sciences
Added to DOAB on : 2020-04-07 23:07:09
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This Special Issue of Children will focus on the migration arc of children from their country of origin through the experience in refugee camps and, finally, to their arrival in in a new home. It will examine the impact experiencing migration as refugees, immigrants or those internally displaced due to war and conflict has on children’s health. Explored topics include adverse health conditions, trauma and mental health, best practice and care coordination. It explores specific populations, such as children with disabilities, unaccompanied minors and child separation at international borders. This Special Issue also includes an examination of new clinical guidelines, the development of new care systems and advocacy for new policies. It also provides a summary of the UN Convention on the Rights of the Child’s specific mandate to provide for the most vulnerable children in need.

Flood Forecasting Using Machine Learning Methods

Authors: --- ---
ISBN: 9783038975489 Year: Pages: 376 DOI: 10.3390/books978-3-03897-549-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Environmental Engineering
Added to DOAB on : 2019-03-08 11:42:05
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This book is a printed edition of the Special Issue Flood Forecasting Using Machine Learning Methods that was published in Water

Keywords

data scarce basins --- runoff series --- data forward prediction --- ensemble empirical mode decomposition (EEMD) --- stopping criteria --- method of tracking energy differences (MTED) --- deep learning --- convolutional neural networks --- superpixel --- urban water bodies --- high-resolution remote-sensing images --- monthly streamflow forecasting --- artificial neural network --- ensemble technique --- phase space reconstruction --- empirical wavelet transform --- hybrid neural network --- flood forecasting --- self-organizing map --- bat algorithm --- particle swarm optimization --- flood routing --- Muskingum model --- machine learning methods --- St. Venant equations --- rating curve method --- nonlinear Muskingum model --- hydrograph predictions --- flood routing --- Muskingum model --- hydrologic models --- improved bat algorithm --- Wilson flood --- Karahan flood --- flood susceptibility modeling --- ANFIS --- cultural algorithm --- bees algorithm --- invasive weed optimization --- Haraz watershed --- ANN-based models --- flood inundation map --- self-organizing map (SOM) --- recurrent nonlinear autoregressive with exogenous inputs (RNARX) --- ensemble technique --- artificial neural networks --- uncertainty --- streamflow predictions --- sensitivity --- flood forecasting --- extreme learning machine (ELM) --- backtracking search optimization algorithm (BSA) --- the upper Yangtze River --- deep learning --- LSTM network --- water level forecast --- the Three Gorges Dam --- Dongting Lake --- Muskingum model --- wolf pack algorithm --- parameters --- optimization --- flood routing --- flash-flood --- precipitation-runoff --- forecasting --- lag analysis --- random forest --- machine learning --- flood prediction --- flood forecasting --- hydrologic model --- rainfall–runoff, hybrid & --- ensemble machine learning --- artificial neural network --- support vector machine --- natural hazards & --- disasters --- adaptive neuro-fuzzy inference system (ANFIS) --- decision tree --- survey --- classification and regression trees (CART), data science --- big data --- artificial intelligence --- soft computing --- extreme event management --- time series prediction --- LSTM --- rainfall-runoff --- flood events --- flood forecasting --- data assimilation --- particle filter algorithm --- micro-model --- Lower Yellow River --- ANN --- hydrometeorology --- flood forecasting --- real-time --- postprocessing --- machine learning --- early flood warning systems --- hydroinformatics --- database --- flood forecast --- Google Maps

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