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Scaffolds in Tissue Engineering - Materials, Technologies and Clinical Applications

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ISBN: 9789535136415 9789535136422 Year: Pages: 332 DOI: 10.5772/66016 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:50

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Biomaterials are often designed to act as scaffolds, i.e., 3D porous templates that support and stimulate the growth of healthy tissue and then safely dissolve once they have performed their functions. This book provides a picture of the current state of the art in the field of scaffolds for tissue engineering, highlighting the potential associated to the latest scientific and technological advancements. The former part of the book focuses on the repair of ""hard"" tissues (primarily bone) by means of bioceramic/glass scaffolds, and the latter deals with the applications of polymeric scaffolds for regenerating ""soft"" tissues and structures including the peripheral nerve, heart, gastric mucosa and pancreas. Special emphasis is given to the challenges associated to scaffold manufacturing, biomimetic properties and cell-scaffold interactions.

Recent Research in Polymerization

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ISBN: 9789535137467 9789535137474 9789535140443 Year: Pages: 216 DOI: 10.5772/intechopen.68265 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:50

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The purpose of this book is to help you concentrate on recent developments in polymerization. The chapters collected in the book are contributions by invited researchers with a long-standing experience in different research areas. I hope that the material presented here is understandable to a broad audience, not only chemists but also scientists from various disciplines. The book contains nine chapters in three sections: (1) ""General Information about Polymerization,"" (2) ""Biomaterial Content Polymer Composites,"" and (3) ""Mechanical Properties of Polymerization."" The book provides detailed and current reviews in these different areas written by experts in their respective fields. This book is expected to be useful for polymer workers and other scientists alike and contribute to the training of current and future researchers, academics, PhD degree students, as well as other scientists.

Cartilage Repair and Regeneration

Authors: ---
ISBN: 9789535137887 9789535137894 9789535140207 Year: Pages: 228 DOI: 10.5772/67903 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:50

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This work is the result of a partnership that began in 2011, when I received for the first time the invitation to be the scientific editor of a book on bone grafting, by the still little publisher known as InTech. Now six years later, InTech has grown and thrived. My respect and warm approval for the quality of the publisher's work only increased. The hyaline cartilage is a tissue that challenges tissue engineering and regenerative medicine because of its avascular nature. In the 11 chapters of this book, the reader will find texts written by researchers working on advanced topics related to basic laboratory research, as well as excellent reviews on the clinical use of currently available therapies.

Tissue Regeneration

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ISBN: 9781789232608 9781789232615 Year: Pages: 206 DOI: 10.5772/intechopen.70922 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:51

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Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).

Muscle Cell and Tissue - Current Status of Research Field

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ISBN: 9781789840056 9781789840063 Year: Pages: 370 DOI: 10.5772/intechopen.71591 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:52

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In order to complete tissue regeneration, various cells (neuronal, skeletal and smooth) interact coordinately with each other. This book, Muscle Cell and Tissue - Current Status of Research Field, deals with current progress and perspectives in a variety of topics on the skeletal and smooth muscle, stem cells, regeneration, disease or therapeutics. Novel applications for cell and tissue engineering including cell therapy, tissue models and disease pathology modeling are introduced. This book also deals with the differentiation/de-differentiation process of vascular smooth muscle cells in health and disease. Furthermore, natural products to reverse metabolic syndromes are descriptively reviewed. These chapters can be interesting for graduate students, teachers, physicians, executives and researchers in the field of molecular biology and regenerative medicine.

Biomaterial-supported Tissue Reconstruction or Regeneration

Authors: --- --- ---
ISBN: 9781838803773 9781838803780 9781838804336 Year: Pages: 162 DOI: 10.5772/intechopen.77756 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:53

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This book is a collection of chapters from different biomaterial experts, including their design, new insights into the molecular basis of their interaction with the organism, and their successful application. The chapters have been organized to illustrate different aspects of multidisciplinary biomaterial science. Thus, this book should give readers a view into the different biomaterial disciplines and methodologies that are needed for specific clinical applications.

Cartilage Tissue Engineering and Regeneration Techniques

Authors: --- ---
ISBN: 9781789238495 9781789238501 9781838807818 Year: Pages: 158 DOI: 10.5772/intechopen.77717 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:53

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Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.

Tissue Engineering

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ISBN: 9789533070797 Year: Pages: 536 DOI: 10.5772/189 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 09:47:08

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The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues that closely match the patient’s needs can be reconstructed from readily available biopsies and subsequently be implanted with minimal or no immunogenicity. This eventually conquers several limitations encountered in tissue transplantation approaches. This book serves as a good starting point for anyone interested in the application of Tissue Engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications.

Applied Tissue Engineering

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ISBN: 9789533076898 Year: Pages: 98 DOI: 10.5772/2630 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 09:47:08

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Tissue engineering, which aims at regenerating new tissues, as well as substituting lost organs by making use of autogenic or allogenic cells in combination with biomaterials, is an emerging biomedical engineering field. There are several driving forces that presently make tissue engineering very challenging and important: 1) the limitations in biological functions of current artificial tissues and organs made from man-made materials alone, 2) the shortage of donor tissue and organs for organs transplantation, 3) recent remarkable advances in regeneration mechanisms made by molecular biologists, as well as 4) achievements in modern biotechnology for large-scale tissue culture and growth factor production. This book was edited by collecting all the achievement performed in the laboratory of oral and maxillofacial surgery and it brings together the specific experiences of the scientific community in these experiences of our scientific community in this field as well as the clinical experiences of the most renowned experts in the fields from all over Nagoya University. The editors are especially proud of bringing together the leading biologists and material scientists together with dentist, plastic surgeons, cardiovascular surgery and doctors of all specialties from all department of the medical school of Nagoya University. Taken together, this unique collection of world-wide expert achievement and experiences represents the current spectrum of possibilities in tissue engineered substitution.

Advances in Biomaterials Science and Biomedical Applications

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ISBN: 9789535110514 Year: Pages: 570 DOI: 10.5772/56420 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 09:47:09

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This contribution book is a collection of reviews and original articles from eminent experts working in the multi- and interdisciplinary arena of biomaterials, ranging from their design to novel uses. From their personal experience, the readers can obtain a stimulating foresight on the potentialities of different synthetic and engineered biomaterials. 21 chapters have been organized to illustrate different aspects of biomaterials science. From advanced means for the characterization and toxicological assessment of new materials, through ""classical"" applications in nanotechnology and tissue engineering, toward novel specific uses of these products, the volume wishes to give readers a view of the wide range of disciplines and methodologies that have been exploited to develop biomaterials with the physical and biological features needed for specific clinical and medical applications.

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