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Neural Circuitry of Behavioral Flexibility: Dopamine and Related Systems

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197958 Year: Pages: 165 DOI: 10.3389/978-2-88919-795-8 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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Abstract

Decades of research have identified a role for dopamine neurotransmission in prefrontal cortical function and flexible cognition. Abnormal dopamine neurotransmission underlies many cases of cognitive dysfunction. New techniques using optogenetics have allowed for ever more precise functional segregation of areas within the prefrontal cortex, which underlie separate cognitive functions. Learning theory predictions have provided a very useful framework for interpreting the neural activity of dopamine neurons, yet even dopamine neurons present a range of responses, from salience to prediction error signaling. The functions of areas like the Lateral Habenula have been recently described, and its role, presumed to be substantial, is largely unknown. Many other neural systems interact with the dopamine system, like cortical GABAergic interneurons, making it critical to understand those systems and their interactions with dopamine in order to fully appreciate dopamine's role in flexible behavior. Advances in human clinical research, like exome sequencing, are driving experimental hypotheses which will lead to fruitful new research directions, but how do (or should?) these clinical findings inform basic research? Following new information from these techniques, we may begin to develop a fresh understanding of human disease states which will inform novel treatment possibilities. However, we need an operational framework with which to interpret these new findings. Therefore, the purpose of this Research Topic is to integrate what we know of dopamine, the prefrontal cortex and flexible behavior into a clear framework, which will illuminate clear, testable directions for future research.

Satellite Altimetry for Earth Sciences

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ISBN: 9783038976806 / 9783038976813 Year: Pages: 484 DOI: 10.3390/books978-3-03897-681-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Physics (General) --- Geophysics and Geomagnetism
Added to DOAB on : 2019-08-28 11:21:27
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Satellite altimetry is a radar technique for measuring the topography of the Earth’s surface. It was initially designed for measuring the ocean’s topography, with reference to an ellipsoid, and for the determination of the marine geoid. Satellite altimetry has provided extremely valuable information on ocean science (e.g., circulation surface geostrophic currents, eddy structures, wave heights, and the propagation of oceanic Kelvin and Rossby waves). With more than 25 years of observations, it is also becoming vital to climate research, providing accurate measurements of sea level variations from regional to global scales. Altimetry has also demonstrated a strong potential for geophysical, cryospheric, and hydrological research and is now commonly used for the monitoring of Arctic and Antarctic ice sheet topography and of terrestrial surface water levels. This book aims to present reviews and recent advances of general interest in the use of radar altimetry in Earth sciences. Manuscripts are related to any aspect of radar altimetry technique or geophysical applications. We also encourage manuscripts resulting from the application of new altimetric technology (SAR, SARin, and Ka band) and improvements expected from missions to be launched in the near future (i.e., SWOT).

Keywords

satellite altimetry --- Envisat --- SARAL --- unsupervised classification --- K-medoids --- Greenland Sea --- Fram Strait --- upper layer thickness --- satellite altimeter --- two-layer ocean model --- South China Sea --- coastal altimetry --- sea surface height --- Jason-2 --- waveform retracking --- satellite altimetry --- inland water --- CryosSat-2 SAR --- Mekong Basin --- water level time series --- classification --- stack data --- altimetry --- Ka-band --- data processing --- calibration --- validation --- altimetry --- SAR --- calibration --- validation --- sea surface height --- coastal altimetry --- validation --- tide gauge --- altimetry --- Ka-band --- oceanography --- hydrology --- ice --- geodesy --- Jason-2 --- Hong Kong coast --- retracking --- X-TRACK --- ALES --- PISTACH --- radar altimetry --- coastal altimetry --- sea surface height --- topography of the intertidal zone --- ERS-2 --- ENVISAT --- SARAL --- CryoSat-2 --- altimetry --- water level --- discharge --- Sentinel-3 --- satellite altimetry --- microwave radiometer --- wet tropospheric correction --- wet path delay --- sensor calibration --- HY-2A --- waveform retracking --- range precision --- marine gravity --- radar altimetry --- waveform --- dielectric permittivity --- soil moisture --- satellite altimetry --- SWOT --- western Mediterranean Sea --- fine scale --- SWOT simulator --- ROMS model --- filtering --- storm surge --- satellite altimetry --- calibration --- numerical modelling --- FVCOM --- ocean tides --- coastal altimetry --- ALES retracker --- ocean geostrophy --- water volume transport --- satellite geodesy --- space gravity --- altimetry --- Argo --- Southern Ocean --- ACC --- lake level --- lake volume --- evaporation --- streamflow --- Gravity Recovery and Climate Experiment (GRACE) --- altimetry --- Landsat --- Aral Sea --- altimetry --- water levels --- validation --- Inner Niger Delta --- altimetry --- orbit decay --- drifting orbit --- geodetic orbit --- leads --- satellite altimetry --- CryoSat-2 --- classification --- peakiness --- polar ocean

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