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Novel Approaches for the Delivery of Anti-HIV Drugs

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ISBN: 9783039219001 / 9783039219018 Year: Pages: 208 DOI: 10.3390/books978-3-03921-901-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General)
Added to DOAB on : 2020-06-09 16:38:57
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HIV/AIDS continues to be one of the most challenging individual and public health concerns of the present day. According to the UNAIDS, nearly 38 million individuals were living with the infection by the end of 2018, while 1.7 million new cases occurred during that same year. In spite of the numerous advances in the development and delivery of antiretroviral agents, both for treatment and prevention, several challenges remain. This book includes original research and review articles on innovative strategies and approaches for the formulation and delivery of anti-HIV drugs, including genetic material and other biopharmaceuticals. Different local and systemic delivery strategies are addressed based on different technologies intended for oral, transdermal, subcutaneous, vaginal, or rectal administration. Authored by eminent scientists in academia and nonprofit organizations involved in the development of antiretroviral drug products, this collection provides useful information for all those involved in HIV/AIDS treatment and prevention.

Keywords

Anti-HIV Drugs --- HIV --- AIDS

Community Nutrition for Developing Countries (a co-publication with UNISA Press)

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ISBN: 9781927356111 9781927356128 9781927356135 9781771990165 Year: Pages: 510 DOI: 10.15215/aupress/9781927356111.01 Language: English
Publisher: Athabasca University Press
Subject: Nutrition and Food Sciences
Added to DOAB on : 2016-08-10 22:45:50
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Nutrition textbooks used by universities and colleges in developing countries have very often been written by scholars who live and work in North America or the United Kingdom. And while the research and information they present is sound, the nutrition-related health challenges with which developing countries must grapple differ considerably from those found in highly industrialized Western nations. The primary aim of Community Nutrition for Developing Countries is to provide a book that meets the needs of nutritionists and other health professionals living and working in developing countries. Written by both scholars and practitioners, the volume draws on their wealth of knowledge, experience, and understanding of nutrition in developing countries to provide nutrition professionals with all the information they require. Each chapter addresses a specific nutrition challenge currently faced by developing countries such as food security, food safety, disease prevention, maternal health, and effective nutrition policy. In addition, the volume serves as an invaluable resource for those developing and implementing nutrition education programmes. With an emphasis on nutritional education as a means to prevent disease and effectively manage health disorders, it is the hope of the nearly three dozen contributors to this work that it will enhance the health and well-being of low-income populations throughout the world.

On Being Human : Where Medicine, Ethics and Spirituality Converge

Authors: --- ---
ISBN: 9791036513862 DOI: 10.4000/books.pum.14901 Language: English
Publisher: Presses de l’Université de Montréal
Subject: Philosophy
Added to DOAB on : 2019-12-06 13:15:44
License: OpenEdition Licence for Books

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At first glance, Western humanism, Japanese Buddhism and modern science have so little in common that the very idea of seeking common ground through dialogue seems overly idealistic. Only a man the calibre of Daisaku Ikeda could bring such a project to fruition. Firmly setting aside cliché and facile answers, he broaches the grand questions that face today's society: cancer, AIDS, death with dignity, in vitro fertilization, biomedical ethics… The responses offered by René Simard, molecular biologist and geneticist, and Guy Bourgeault, bioethicist, are insightful and compelling. Their discussions cut through linguistic and cultural barriers to present a vision of the potential – an the inherent challenges – of being human.

Keywords

medical ethics --- bioethics --- AIDS --- cancer --- sickness --- right to die

Film and the Chinese Medical Humanities

Authors: --- ---
ISBN: 9781138580299 Year: Pages: 266 Language: English
Publisher: Taylor & Francis Grant: Wellcome Trust
Subject: Medicine (General) --- Media and communication --- Performing Arts --- Sociology
Added to DOAB on : 2020-05-26 07:02:39
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Film and the Chinese Medical Humanities is the first book to reflect on the power of film in representing medical and health discourse in China in both the past and the present, as well as in shaping its future. Drawing on both feature and documentary films from mainland China, the chapters each engage with the field of medicine through the visual arts. They cover themes such as the history of doctors and their concepts of disease and therapies, understanding the patient experience of illness and death, and establishing empathy and compassion in medical practice, as well as the HIV/AIDs epidemic during the 1980s and 90s and changing attitudes towards disability. Inherently interdisciplinary in nature, the contributors therefore provide different perspectives from the fields of history, psychiatry, film studies, anthropology, linguistics, public health and occupational therapy, as they relate to China and people who identify as Chinese. Their combined approaches are united by a passion for improving the cross-cultural understanding of the body and ultimately healthcare itself.

Civic Insecurity: Law, Order and HIV in Papua New Guinea

Authors: ---
Book Series: Studies in State and Society in the Pacific ISBN: 9781921666612 Year: Pages: 338 DOI: 10.26530/OAPEN_458878 Language: English
Publisher: ANU Press
Subject: Law --- Political Science
Added to DOAB on : 2012-06-14 11:46:24
License: ANU Press

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Papua New Guinea has a complex ‘law and order’ problem and an entrenched epidemic of HIV. This book explores their interaction. It also probes their joint challenges and opportunities—most fundamentally for civic security, a condition that could offersome immunity to both. This book is a valuable and timely contribution to a limited but growing body of scholarship in the social and structural contexts of HIV epidemiology in Papua New Guinea. The volume offers a unique collection of interdisciplinary insights on the connections between law and order and the HIV epidemic and is presented in a manner accessible to a wide audience, scholars and lay people alike… Significantly, this is the first volume to critically examine the complex and inexorable links between HIV, gender, violence, and security within a theoretical framework thv at illuminates the challenges of the epidemic for PNG’s future cohesion and stability as a young nation…The importance of this courageous book cannot be overstated. While it communicates an urgent and potent message about the need for immediate action … it offers insightful reflections on the processes and possibilities of social transformation that undoubtedly will have enduring scholarly and practical value. Dr Katherine Lepani, Social Foundations of Medicine, The Australian National University.

Movement, Knowledge, Emotion

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ISBN: 9781921862397 Year: Pages: 205 DOI: 10.26530/OAPEN_459377 Language: English
Publisher: ANU Press
Subject: Public Health --- Political Science
Added to DOAB on : 2012-06-14 11:46:25
License: ANU Press

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This book is about community activism around HIV/AIDS in Australia. It looks at the role that the gay community played in the social, medical and political response to the virus. Drawing conclusions about the cultural impact of social movements, the author argues that AIDS activism contributed to improving social attitudes towards gay men and lesbians in Australia, while also challenging some entrenched cultural patterns of the Australian medical system, allowing greater scope for non-medical intervention into the domain of health and illness. The book documents an important chapter in the history of public health in Australia and explores how HIV/AIDS came to be a defining issue in the history of gay and lesbian rights in Australia.

Immunomodulatory Effects of Drugs for Treatment of Immune-Related Diseases

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889452880 Year: Pages: 108 DOI: 10.3389/978-2-88945-288-0 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Allergy and Immunology
Added to DOAB on : 2018-02-27 16:16:44
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More than 90% of diseases possess immunological abnormalities. Disorders such as inflammation, hypersensitivity, autoimmunity and immunodeficiency are simple examples of how the immune system misinterprets its surroundings and goes awry. Multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel diseases, among many others are manifestations of immune cells attacking normal tissues. On the other hand, damping the immune system leads to diseases such as cancer, AIDS, and severe combined immunodeficiency. The last ten years witnessed an explosion in developing drugs that target the immune system. Several novel monoclonal antibodies have been approved for treatment of various diseases confirming that personalized medicine approach is robust in combating diseases. Hence, the future holds great promise for using personalized and targeted medicine rather than generalized medications that, in most circumstances, proven to be ineffective and characteristically exert side effects. Approaches such as generating novel adjuvants that can stimulate the immune system without harmful side effects, targeting inflammatory cytokines and chemokines, harnessing and activating innate immune cells such as natural killer cells or dendritic cells, are examples of future approaches to treat autoimmune diseases, AIDS, and various forms of cancer resulting from chronic inflammation. More recently, targeting immune checkpoint molecules have shown therapeutic response against lung cancer and melanoma. Identifying molecules involved in autophagy is another example of how personalized medicine might help treat patients with refractory asthma and autoimmune diseases. This topic introduces the reader to these novel approaches of manipulating the immune system and developing targeted therapeutic strategies for treatment of various diseases.

Virgil, Aeneid 11 (Pallas & Camilla), 1–224, 498–521, 532–96, 648–89, 725–835. Latin Text, Study Aids with Vocabulary, and Commentary

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ISBN: 9781783746002 9781783746026 Year: Pages: 596 DOI: 10.11647/OBP.0158 Language: English
Publisher: Open Book Publishers
Subject: Languages and Literatures
Added to DOAB on : 2019-01-28 13:47:15
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A dead boy (Pallas) and the death of a girl (Camilla) loom over the opening and the closing part of the eleventh book of the Aeneid. Following the savage slaughter in Aeneid 10, the book opens in a mournful mood as the warring parties revisit yesterday’s killing fields to attend to their dead. One casualty in particular commands attention: Aeneas’ protégé Pallas, killed and despoiled by Turnus in the previous book. His death plunges his father Evander and his surrogate father Aeneas into heart-rending despair – and helps set up the foundational act of sacrificial brutality that caps the poem, when Aeneas seeks to avenge Pallas by slaying Turnus in wrathful fury. Turnus’ departure from the living is prefigured by that of his ally Camilla, a maiden schooled in the martial arts, who sets the mold for warrior princesses such as Xena and Wonder Woman. In the final third of Aeneid 11, she wreaks havoc not just on the battlefield but on gender stereotypes and the conventions of the epic genre, before she too succumbs to a premature death. In the portions of the book selected for discussion here, Virgil offers some of his most emotive (and disturbing) meditations on the tragic nature of human existence – but also knows how to lighten the mood with a bit of drag.This course book offers the original Latin text, vocabulary aids, study questions, and an extensive commentary. Designed to stretch and stimulate readers, Ingo Gildenhard’s volume will be of particular interest to students of Latin studying for A-Level or on undergraduate courses. It extends beyond detailed linguistic analysis to encourage critical engagement with Virgil’s poetry and the most recent scholarly thought.King's College, Cambridge, has generously contributed to this publication.

Cicero, Philippic 2, 44–50, 78–92, 100–119: Latin Text, Study Aids with Vocabulary, and Commentary

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Book Series: Classics Textbooks ISSN: 20542437 20542445 ISBN: 9781783745890 9781783745913 Year: Volume: 1 Pages: 488 DOI: https://doi.org/10.11647/OBP.0156 Language: English
Publisher: Open Book Publishers
Subject: Languages and Literatures
Added to DOAB on : 2018-09-01 16:05:31
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Cicero composed his incendiary Philippics only a few months after Rome was rocked by the brutal assassination of Julius Caesar. In the tumultuous aftermath of Caesar’s death, Cicero and Mark Antony found themselves on opposing sides of an increasingly bitter and dangerous battle for control. Philippic 2 was a weapon in that war.Conceived as Cicero’s response to a verbal attack from Antony in the Senate, Philippic 2 is a rhetorical firework that ranges from abusive references to Antony’s supposedly sordid sex life to a sustained critique of what Cicero saw as Antony’s tyrannical ambitions. Vituperatively brilliant and politically committed, it is both a carefully crafted literary artefact and an explosive example of crisis rhetoric. It ultimately led to Cicero’s own gruesome death.This course book offers a portion of the original Latin text, vocabulary aids, study questions, and an extensive commentary. Designed to stretch and stimulate readers, Ingo Gildenhard’s volume will be of particular interest to students of Latin studying for A-Level or on undergraduate courses. It extends beyond detailed linguistic analysis to encourage critical engagement with Cicero, his oratory, the politics of late-republican Rome, and the transhistorical import of Cicero’s politics of verbal (and physical) violence.

Empirical Analysis of Determinants, Distribution and Dynamics of Poverty

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Book Series: Goettinger Studien zur Entwicklungsoekonomik / Goettingen Studies in Development Economics ISBN: 9783631573983 Year: Pages: 204 DOI: 10.3726/b13880 Language: English
Publisher: Peter Lang International Academic Publishing Group
Subject: Economics --- Political Science
Added to DOAB on : 2019-01-15 13:32:27
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Poverty and inequality persist in many dimensions in the developing world. In order to understand the determinants of poverty and its distribution between and within countries, it is necessary to know its dimensions and the channels through which poverty and inequality affect human well-being. This book analyzes the spatial disparities of the outcomes and determinants of poverty, the interdependencies of dimensions of poverty, the distribution of progress in human development over the population and the dynamics of poverty risk over time. The study takes into account the global spread of poverty. Based on cross-country comparisons of countries from Africa, Latin America, and South Asia, this study does not only consider on average outcomes and determinants of different indicators of human well-being, but also examines their distribution between and within countries.

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