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Weißbuch Multiple Sklerose: Versorgungssituation in Deutschland

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ISBN: 9783662492031 9783662492048 Year: Pages: 145 DOI: 10.1007/978-3-662-49204-8 Language: German
Publisher: Springer
Subject: Neurology --- Biotechnology --- Therapeutics
Added to DOAB on : 2017-01-24 17:34:34
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Die Multiple Sklerose (MS) ist die häufigste entzündlich degenerative Erkrankung des zentralen Nervensystems im jungen Erwachsenenalter. Die Erkrankung ist bis heute nicht heilbar. In den vergangenen Jahren hat sich eine Vielzahl neuer therapeutischer Optionen aufgetan.Dieses Weißbuch hat das Ziel, aktuelles Wissen über die Erkrankung MS und ihrer Versorgung in Deutschland sachlich und umfassend darzustellen. Es beinhaltetInformationen zum Krankheitsbild, zur Epidemiologie und zu seiner gesundheitsökonomischen Relevanz.Aktuelle Entwicklungen und Behandlungsempfehlungen sind der realen Inanspruchnahme und den vorhandenen Angebotskapazitäten diagnostischer und therapeutischer Möglichkeiten gegenübergestellt.Die relevanten Akteure des Versorgungsgeschehens und wichtige Prozesse der Versorgungsgestaltung werden beschrieben.Namhafte medizinische Experten und Vertreter der gesetzlichen Krankenkasse haben das Weißbuch als Autoren begleitet. Mit seiner umfassenden Darstellung des Themas liefert das Buch wichtige Anstöße zum Verständnis der Erkrankung sowie für die zukünftige Gestaltung der Versorgung von Menschen mit MS. Es richtet sich an Gestalter und Vertreter des Versorgungsgeschehens aus Krankenkassen, Politik, Medizin, Gesundheitswissenschaften sowie an Patientenvertreter und Medienvertreter.

Keywords

Neurology --- Biotechnology

The Gene Ontology Handbook

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Book Series: Methods in Molecular Biology ISSN: 1064-3745 ISBN: 9781493937417 9781493937431 Year: Pages: 305 DOI: 10.1007/978-1-4939-3743-1 Language: English
Publisher: Springer
Subject: Biology
Added to DOAB on : 2017-02-24 12:38:17
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This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.

Education and Ethics in the Life Sciences: Strengthening the Prohibition of Biological Weapons

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Book Series: Practical Ethics and Public Policy Monograph ISBN: 9781921666391 Year: Pages: 222 DOI: 10.26530/OAPEN_459095 Language: English
Publisher: ANU Press
Subject: Education --- Philosophy
Added to DOAB on : 2012-06-14 11:46:24
License: ANU Press

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At the start of the twenty-first century, warnings have been raised in some quarters about how – by intent or by mishap – advances in biotechnology and related fields could aid the spread of disease. Science academics, medical organisations, governments, security analysts, and others are among those that have sought to raise concern. Education and Ethics in the Life Sciences examines a variety of attempts to bring greater awareness to security concerns associated with the life sciences. It identifies lessons from practical initiatives across a wide range of national contexts as well as more general reflections about education and ethics. The eighteen contributors bring together perspectives from a diverse range of fields – including politics, virology, sociology, ethics, security studies, microbiology, and medicine – as well as their experiences in universities, think tanks and government.&#xD;&#xD;In offering their assessment about what must be done and by whom, each chapter addresses a host of challenging practical and conceptual questions. Education and Ethics in the Life Sciences will be of interest to those planning and undertaking training activities in other areas. In asking how education and ethics are being made to matter in an emerging area of social unease, it will also be of interest to those with more general concerns about professional conduct.

Keywords

biotechnology --- prevention --- ethics --- education

Weißbuch Gelenkersatz: Versorgungssituation bei endoprothetischen Hüft- und Knieoperationen in Deutschland

Authors: ---
ISBN: 9783662529041 9783662532607 Year: Pages: 142 DOI: 10.1007/978-3-662-53260-7 Language: German
Publisher: Springer
Subject: Medicine (General)
Added to DOAB on : 2017-02-14 10:01:32
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Dieses Weißbuch beschreibt die Versorgungssituation bei endoprothetischen Hüft- und Knieoperationen in Deutschland. Gelenkersatzoperationen im Bereich der Hüfte und des Knies zählen zu den häufigen Operationen, die zumeist wegen eines altersbedingten Gelenkverschleißes, der Arthrose oder bei Schenkelhalsfrakturen, notwendig sind. Angesichts des demografischen Wandels werden die Ansprüche an die Versorgung der Betroffenen und die Verfahren steigen.

Keywords

orthopedics --- surgery --- medicine --- biotechnology

Strategien biotechnischer Innovation. Analysen, Konzepte und empirische Befunde

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ISBN: 9783937816340 Year: Pages: 167 DOI: 10.15460/HUP.63 Language: German
Publisher: Hamburg University Press
Subject: Agriculture (General)
Added to DOAB on : 2019-01-15 13:33:23

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Over the past decade, efforts been have intensified to establish a viable location for modern biotechnologies in the Hamburg region. The growing intensity of Hamburg's biotechnological support can be seen as a reflection on the drastic slump of newly founded biotechnology companies that took place in previous years. Numerous companies disappeared from the scene after a short period of time despite good concepts and good technologies. Against this background the lecture series "Strategies of Biotechnological Innovation" was held in the winter semester 2004/2005 at the Research Center for Biotechnology, Society and Environment (BIOGUM) of the University of Hamburg. Its aim was to examine the possibilities, problems and limitations of innovation management from different perspectives. The texts of this volume are based on lectures given by the contributors in the context of this lecture series.

Science and Technology Governance and Ethics: A Global Perspective from Europe, India and China

Authors: --- --- ---
ISBN: 9783319146928 9783319146935 Year: Volume: 1 Pages: 173 DOI: 10.1007/978-3-319-14693-5 Language: English
Publisher: Springer
Subject: Chemical Engineering --- Business and Management --- Philosophy --- Manufactures
Added to DOAB on : 2015-07-24 16:44:14
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This book analyzes the possibilities for effective global governance of science in Europe, India and China. Authors from the three regions join forces to explore how ethical concerns over new technologies can be incorporated into global science and technology policies. The first chapter introduces the topic, offering a global perspective on embedding ethics in science and technology policy. Chapter Two compares the institutionalization of ethical debates in science, technology and innovation policy in three important regions: Europe, India and China. The third chapter explores public perceptions of science and technology in these same three regions. Chapter Four discusses public engagement in the governance of science and technology, and Chapter Five reviews science and technology governance and European values. The sixth chapter describes and analyzes values demonstrated in the constitution of the People’s Republic of China. Chapter Seven describes emerging evidence from India on the uses of science and technology for socio-economic development, and the quest for inclusive growth. In Chapter Eight, the authors propose a comparative framework for studying global ethics in science and technology. The following three chapters offer case studies and analysis of three emerging industries in India, China and Europe: new food technologies, nanotechnology and synthetic biology. Chapter 12 gathers all these threads for a comprehensive discussion on incorporating ethics into science and technology policy. The analysis is undertaken against the backdrop of different value systems and varying levels of public perception of risks and benefits. The book introduces a common analytical framework for the comparative discussion of ethics at the international level. The authors offer policy recommendations for effective collaboration among the three regions, to promote responsible governance in science and technology and a common analytical perspective in ethics.

Enzymes from Extreme Environments

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198306 Year: Pages: 103 DOI: 10.3389/978-2-88919-830-6 Language: English
Publisher: Frontiers Media SA
Subject: Biotechnology --- General and Civil Engineering
Added to DOAB on : 2016-01-19 14:05:46
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Enzymes are nature’s biocatalysts empowered with high catalytic power and remarkable substrate specificity. Enzymes perform a wide range of functions throughout nature, and guide the biochemistry of life with great precision. The majority of enzymes perform under conditions considered normal for mesophilic, neutrophilic, terrestrial microorganisms. However, the Earth’s biosphere contains several regions that are extreme in comparison, such as hypersaline lakes and pools, hydrothermal vents, cold oceans, dry deserts and areas exposed to intensive radiation. These areas are inhabited by a large number of extremophilic microorganisms which produce enzymes capable of functioning in unusual conditions. There is an increasing biotechnological and industrial demand for enzymes stable and functioning in harsh conditions, and over the past decade screening for, isolation and production of enzymes with unique and extreme properties has become one of the foremost areas of biotechnology research. The development of advanced molecular biology tools has facilitated the quest for production of enzymes with optimized and extreme features. These tools include large-scale screening for potential genes using metagenomics, engineering of enzymes using computational techniques and site-directed mutagenesis and molecular evolution techniques. The goal of this Research Topic is to present reports on latest advances in enzymes from all types of extreme environments. Contributions dealing with isolation of enzymes from extremophilic microorganisms or directly from natural environments, screening for and expression of enzymes with extreme properties using metagenomic approaches are welcome. In addition, contributions dealing with all forms of biocatalyst production and improvement are welcome, such as fermentation technology, protein engineering, directed evolution, rational design, and immobilization techniques.

Synthetic biology applications in industrial microbiology

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193424 Year: Pages: 129 DOI: 10.3389/978-2-88919-342-4 Language: English
Publisher: Frontiers Media SA
Subject: Environmental Sciences --- Biotechnology --- General and Civil Engineering --- Microbiology --- Science (General)
Added to DOAB on : 2016-03-10 08:14:32
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Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.

Low-Cost Methods for Molecular Characterization of Mutant Plants: Tissue Desiccation, DNA Extraction and Mutation Discovery: Protocols

Authors: --- --- --- --- et al.
ISBN: 9783319162584 9783319162591 Year: Pages: 35 DOI: 10.1007/978-3-319-16259-1 Language: English
Publisher: Springer
Subject: Biotechnology --- Plant Sciences --- Manufactures --- Chemical Engineering --- Pharmacy and materia medica
Added to DOAB on : 2016-04-12 17:07:01
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Open Access provided with a grant from the International Atomic Energy Agency.This book offers low-cost and rapid molecular assays for the characterization of mutant plant germplasm. Detailed protocols are provided for the desiccation of plant tissues; the extraction of high-quality DNA for downstream applications; the extraction of single-strand-specific nucleases for single nucleotide polymorphism; and small insertion/deletion discovery using standard agarose gel electrophoresis. The methods described can be applied in any laboratory equipped for basic molecular biology and do away with the need for expensive freezers and toxic organic compounds. With the appropriate validation of sample quality and longevity, they can provide sufficient DNA for a variety of molecular applications, such as marker studies and TILLING, at approximately one tenth of the cost per sample when compared to commercial kits.

Biotechnologies for Plant Mutation Breeding: Protocols

Authors: --- --- ---
ISBN: 9783319450193 9783319450216 Year: Pages: 340 DOI: 10.1007/978-3-319-45021-6 Language: English
Publisher: Springer
Subject: Manufactures --- Chemical Engineering --- Biotechnology --- Therapeutics
Added to DOAB on : 2017-03-08 13:33:36
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This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular characterization of mutant plants that are suitable for laboratories in developing countries. The collection of protocols equips users with the techniques they need in order to start a program on mutation breeding or functional genomics using both forward and reverse-genetic approaches. Methods are provided for seed and vegetatively propagated crops (e.g. banana, barley, cassava, jatropha, rice) and can be adapted for use in other species.

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