Search results: Found 2

Listing 1 - 2 of 2
Sort by
Frontiers in Brain Based Therapeutic Interventions and Biomarker Research in Child and Adolescent Psychiatry

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199549 Year: Pages: 107 DOI: 10.3389/978-2-88919-954-9 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Psychiatry
Added to DOAB on : 2016-01-19 14:05:46
License:

Loading...
Export citation

Choose an application

Abstract

Developmental neuroscience research is on the cusp of unprecedented advances in the understanding of how variations in brain structure and function within neural circuits confer risk for symptoms of childhood psychiatric disorders. Novel dimensional approaches to illness classification, the availability of non-invasive, diverse and increasingly sophisticated methods to measure brain structure and function in humans in vivo, and advances in genetics, animal model and multimodal research now place brain-based biomarkers within reach in the field of psychiatry. These advances hold great promise for moving neuroscience research into the clinical realm. One exciting new area of translational research in child and adolescent psychiatry, is in the use of a variety of neuroscience research tools to track brain response to clinical intervention. Examples of this include: using longitudinal neuroimaging techniques to track changes in white matter microstructure following a training intervention for children with poor reading skills, or using functional imaging to compare brain activity before and after children with bipolar disorder begin taking psychotropic medication treatment. Brain stimulation is another cutting-edge research area where brain response to therapeutic intervention can be closely tracked with electroencephalography or other brain imaging modalities. Research using neuroscience tools to track brain response to clinical interventions is beginning to yield novel insights into the etiopathogenesis of psychiatric illness, and is providing preliminary feedback around how therapeutic interventions work in the brain to bring about symptom improvement. Using these novel approaches, neuroscience research may soon move into the clinical realm to target early pathophysiology, and tailor treatments to both individuals and specific neurodevelopmental trajectories, in an effort to alter the course of development and mitigate risk for a lifetime of morbidity and ineffective treatments. Excitement and progress in these areas must be tempered with safety and ethical considerations for these vulnerable populations. This research topic focuses on efforts to use neuroscience research tools to identify brain-based biomarkers of therapeutic response in child and adolescent psychiatry.

Psychomotor symptomatology in psychiatric illnesses

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197255 Year: Pages: 137 DOI: 10.3389/978-2-88919-725-5 Language: English
Publisher: Frontiers Media SA
Subject: Psychiatry --- Medicine (General)
Added to DOAB on : 2016-04-07 11:22:02
License:

Loading...
Export citation

Choose an application

Abstract

Psychomotor symptoms are those symptoms that are characterized by deficits in the initiation, execution and monitoring of movements, such as psychomotor slowing, catatonia, neurological soft signs (NSS), reduction in motor activity or extrapyramidal symptoms (EPS). These symptoms have not always received the attention they deserve although they can be observed in a wide range of psychiatric illnesses, including mood disorders, psychotic disorders, anxiety disorders, pervasive developmental disorders and personality disorders. Nevertheless, these symptoms seem to have prognostic value on clinical and functional outcome in several pathologies. In the late 19th century, the founding fathers of modern psychiatry (including Kahlbaum, Wernicke, Kraepelin and Bleuler) had a strong focus on psychomotor abnormalities in their description and definitions of psychiatric illnesses and systematically recognized these as core features of several psychiatric pathologies. Nevertheless, emphasis on these symptoms has reduced substantially since the emergence of psychopharmacology, given the association between antipsychotics or antidepressants and medication-induced motor deficits. This has resulted in the general idea that most if not all psychomotor deficits were merely side effects of their treatment rather than intrinsic features of the illness. Yet, the last two decades a renewed interest in these deficits can be observed and has yielded an exponential growth of research into these psychomotor symptoms in several psychiatric illnesses. This recent evolution is also reflected in the increased appreciation of these symptoms in the DSM-5. As a result of this increased focus, new insights into the clinical and demographical presentation, the etiology, the course, the prognostic value as well as treatment aspects of psychomotor symptomatology in different illnesses has emerged. Still, many new questions arise from these findings. This research topic is comprised of all types of contributions (original research, reviews, and opinion piece) with a focus on psychomotor symptomatology in a psychiatric illness, especially research focusing on one or more of the following topics: the clinical presentation of the psychomotor syndrome; the course through the illness; the diagnostical specificity of the syndrome; the underlying neurobiological or neuropsychological processes; new assessment techniques; pharmacological or non-pharmacological treatment strategies.

Listing 1 - 2 of 2
Sort by
Narrow your search

Publisher

Frontiers Media SA (2)


License

CC by (2)


Language

english (2)


Year
From To Submit

2016 (1)

2015 (1)