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Isolation and Structure Elucidation of Bioactive Compounds (Dedicated to the memory of the late Professor Charles D. Hufford)

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ISBN: 9783038977803 9783038977810 Year: Pages: 276 DOI: 10.3390/books978-3-03897-781-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-04-25 16:37:17
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Abstract

We are very pleased to introduce the Book Version of our Special Issue in Molecules dedicated to the memory of the late Professor Dr. Charles D. Hufford. The issue has been a huge success, with 22 full-length peer-reviewed papers and a tribute by Professor Alice M.Clark. Authors, reviewers, and collaborators from many countries across the worldhave contributed to this endeavour, and we are truly grateful to all. This Special Issue isrepresentative of the broad impact that “Charlie” had on the field of bioactive naturalproducts. This Special Issue comprises papers from Professor Hufford’s former students,colleagues, and collaborators throughout the world who have utilized a wide array ofstate-of-the-art techniques to examine diverse natural sources to isolate and identify avariety of natural products with a wide spectrum of biological activities, including somenew microbial transformations and insights into bioactive molecules. Many new bioactive compounds are described and reported here for the first time. Bioactivities reportedinclude cytotoxicity, antimicrobial activity, anti-inflammatory activity, antileishmanialactivity, antitrypanosomal activity, antimalarial activity, analgesic activity, and beneficialliver activities, just to name a few. This Special Issue will undoubtedly have a lasting impact on the field of bioactive natural products, as exemplified by the career of Dr. Hufford.Lastly, without the timely and outstanding contributions from all of you, this Special Issue would not have been possible. We thank you all very much for your contributions and your time devoted to this Special Issue in memory of a special person. Finally, we express ourgratitude and thanks to the journal Molecules and their excellent team of expert reviewers for giving us the support and opportunity to make this Special Issue a huge success!

Keywords

fusidic acid --- Cunninghamella echinulata --- C-26-oxidation --- C-27-oxidation --- Morus alba L. --- aldose reductase inhibitor --- neuroprotective agent --- natural products --- Mitracarpus scaber Zucc. --- pentalogin --- anti-inflammatory --- MS/MS --- Il-8 --- Crinum amabile --- augustine N-oxide --- buphanisine N-oxide --- biological activities --- Cryptococcus neoformans --- cryptococcosis --- HepG2 --- Prosopis glandulosa --- prosopilosidine --- amphotericin B --- fluconazole --- resveratrol --- dietary supplement --- gastro-resistant --- microparticles --- obesity --- HPLC --- Jatropha pelargoniifolia --- alkaloids --- flavonoids --- coumarinolignans --- diterpenes --- anti-inflammatory --- analgesic --- antipyretic --- Cochlospermum vitifolium --- Cochlospermaceae --- flavonoids --- lignans --- aromatic compounds --- carotenoids --- sterols --- liver activity --- Arthrinium sp. --- chromone --- polyketide --- antioxidant activity --- Rubiaceae --- jenipapo --- HPLC-ESI-IT-MS/MS --- flavonoids glycosides --- Baccharis --- antimalarial activity --- antitrypanosomal activity --- insecticidal activity --- GC/MS --- DNA barcoding --- microscopy --- antibacterial --- channel catfish --- columnaris disease --- Flavobacterium columnare --- stilbenes --- muscadine --- pyranoanthocyanin --- anti-leishmanial activity --- Leishmania donovani --- maleimides --- cytotoxicity --- SAR --- phlorogluciniol --- acylphloroglucinol --- anti-inflammatory --- iNOS --- NF-?B --- endophytic fungi --- sesterterpene --- cytotoxic activity --- pancreatic cancer --- Stevia rebaudiana --- diterpene glycosides --- rebaudioside A isomers --- 13(S)-hydroxyatisenoic acid derivative --- iso-stevioside X-ray structure --- Litsea cubeba --- cytotoxicity --- isolation and elucidation --- lignans --- antimicrobial resistance --- multi-drug resistant (MDR) --- methicillin resistant Staphylococcus aureus (MRSA) --- Zingiber monatnum --- terpenes --- (E)-8(17),12-labdadiene-15,16-dial --- zerumbol --- microbial transformation --- hop prenylflavanone --- isoxanthohumol --- cardiomyogenesis --- factor VII --- factor X --- inflammation --- thrombosis --- vasculogenesis --- herbal medicine --- n/a --- Nemania --- Xylariaceae --- Torreya taxifolia --- plant pathogenic and endophytic fungi --- cytochalasins --- malaria --- cytotoxicity --- phytotoxicity --- acacetin 7-methyl ether --- acacetin --- monoamine oxidase-A --- monoamine oxidase-B --- molecular docking --- molecular dynamics --- neurological disorder --- Turnera diffusa

Systematics and Phylogeny of Weevils

Authors: --- ---
ISBN: 9783038976561 9783038976578 Year: Pages: 474 DOI: 10.3390/books978-3-03897-657-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-04-25 16:37:17
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Abstract

This Special Issue on the Systematics and Phylogeny of Weevils presents 31 new research papers on one of the most diverse and successful groups of animals on Earth, the beetle superfamily Curculionoidea. It was in part inspired to commemorate the extraordinary life and scientific achievements of Guillermo (“Willy”) Kuschel (1918–2017), who shaped this field of science over the last century like no other weevil systematist. The papers in this memorial issue span weevil faunas from all over the globe, including South and Central America, Africa, Europe and the Near East, South-East Asia, New Guinea, Australia and New Zealand. They include major advances on the phylogeny and classification of the “broad-nosed” weevils (Entiminae), on the weevils associated with American cycads and on the unique extinct weevil fauna preserved in the 100-million-year-old Burmese amber, when weevils started to diversify alongside the oldest angiosperm plants. They comprise a tribute to Willy Kuschel, the proceedings of a weevil symposium held in his honor in 2016 in Orlando, Florida, 24 systematic studies (including seven phylogenetic analyses) and five other contributions on the diversity, biology, distribution, evolution and fossil history of weevils. In the papers collated in this volume, 30 new genera and 92 new species of weevils are described and a new family of extinct weevils is recognized.

Keywords

constraint analysis --- AU test --- SH test --- KH test --- mitochondrial genomes --- Curculionoidea --- Curculionidae --- Cossoninae --- Rhyncolini --- Rhyncolina --- taxonomy --- new species --- mature larva --- morphology --- host plant --- Cape Verde --- biogeography --- microclimate --- species competition --- taxonomy --- South Africa --- Namibia --- weevils --- new taxa --- spermatheca --- Mimaulus --- Spartecerus --- spatio-temporal diffusion --- specialist weevils --- parasitic plants --- co-dispersal through space and time --- stable populations --- Coleoptera --- Curculionidae --- Curculioninae --- Acentrusini --- phylogeny --- Coleoptera --- Curculionidae --- Brachycerinae --- Tanysphyrini --- Afroryzophilus --- new species --- Afrotropical region --- Belidae --- Oxycoryninae --- Erotylidae --- Pharaxonothinae --- cycad pollination --- Alien --- invasive --- exotic --- biodiversity --- Patagonia --- Pinus radiata --- Eucalyptus --- taxonomy --- weevil --- new species --- Araucariaceae --- Hoop Pine --- Klinki Pine --- Australia --- Papuan region --- Neotropical region --- broad-nosed weevils --- Naupactini --- Pantomorus-Naupactus complex --- phylogeny --- COI --- combined evidence --- 1K Weevils Project --- biogeography --- classification --- Curculionidae --- Curculionoidea --- fossils --- Guillermo Kuschel --- morphology --- molecular phylogenetics --- DNA barcoding --- phylogeny --- phytophagy --- weevils --- Dichotrachelini --- systematics --- morphology --- evolution --- mt-Cox1 --- Cryptoplini --- taxonomy --- weevils --- tectal aedeagus --- Kuschelorhynchus --- Macadamia --- Syzygium --- Australia --- New Guinea --- Curculionidae --- biological control --- target host --- non-target host --- taxonomy --- phylogeny --- Sclerocardius --- Sclerocardiini --- taxonomy --- systematics --- elytro-tergal stridulation --- taxonomy --- identification --- diagnostics --- pollination --- flightlessness --- Curculionoidea --- weevil --- hygrophilous --- aquatic --- semi-aquatic --- riparian --- key --- Israel --- Curculionidae --- Anchonini --- Molytinae --- Aethiopacorep africanus --- neotype --- Titilayo --- Titilayo barclayi --- Titilayo garnerae --- Titilayo geiseri --- Titilayo takanoi --- Titilayo perrinae --- Titilayo saotomense --- Titilayo turneri --- taxonomy --- distribution --- taxonomy --- weevil --- new species --- Australia --- Papuan region --- Araceae --- biodiversity --- ecology --- faunal inventories --- mimicry --- phenology --- Brachycerinae --- Tanysphyrini --- Afroryzophilus --- new species --- Afrotropical region --- Cossoninae --- Rhyncolini --- Rhyncolina --- taxonomy --- new species --- Aciphylla --- Chatham Islands --- integrative taxonomy --- Poor Knights Islands --- weevils --- Urodontinae --- Urodontidius --- genitalia --- larva --- life history --- galling habit --- silk production --- taxonomy --- South Africa --- Namibia --- weevils --- new taxa --- Broad-nosed weevils --- Entiminae --- tribal relationships --- combined evidence --- ribosomal markers --- structural alignment --- mitochondrial COI --- adults --- larvae --- biography --- obituary --- weevils --- systematics --- publications --- Borneo --- tropical forest canopies --- fogging --- diversity --- forest disturbance --- weevil fauna --- longhorned beetle (Cerambycidae) --- new species --- Curculionoidea --- Mesophyletidae --- Cretaceous --- taxonomy --- morphology --- CT scanning --- amber preparation --- angiosperm associations --- weevil larvae --- palm weevils --- invasive species --- comparative morphology --- homonym --- taxonomy --- Curculionoidea --- Mesophyletidae --- Cretaceous

Systematics and Phylogeny of Weevils

Authors: --- ---
ISBN: 9783038976684 9783038976691 Year: Pages: 458 DOI: 10.3390/books978-3-03897-669-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-04-25 16:37:17
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Abstract

This Special Issue on the Systematics and Phylogeny of Weevils presents 31 new research papers on one of the most diverse and successful groups of animals on Earth, the beetle superfamily Curculionoidea. It was in part inspired to commemorate the extraordinary life and scientific achievements of Guillermo (“Willy”) Kuschel (1918–2017), who shaped this field of science over the last century like no other weevil systematist. The papers in this memorial issue span weevil faunas from all over the globe, including South and Central America, Africa, Europe and the Near East, South-East Asia, New Guinea, Australia and New Zealand. They include major advances on the phylogeny and classification of the “broad-nosed” weevils (Entiminae), on the weevils associated with American cycads and on the unique extinct weevil fauna preserved in the 100-million-year-old Burmese amber, when weevils started to diversify alongside the oldest angiosperm plants. They comprise a tribute to Willy Kuschel, the proceedings of a weevil symposium held in his honor in 2016 in Orlando, Florida, 24 systematic studies (including seven phylogenetic analyses) and five other contributions on the diversity, biology, distribution, evolution and fossil history of weevils. In the papers collated in this volume, 30 new genera and 92 new species of weevils are described and a new family of extinct weevils is recognized.

Keywords

constraint analysis --- AU test --- SH test --- KH test --- mitochondrial genomes --- Curculionoidea --- Curculionidae --- Cossoninae --- Rhyncolini --- Rhyncolina --- taxonomy --- new species --- mature larva --- morphology --- host plant --- Cape Verde --- biogeography --- microclimate --- species competition --- taxonomy --- South Africa --- Namibia --- weevils --- new taxa --- spermatheca --- Mimaulus --- Spartecerus --- spatio-temporal diffusion --- specialist weevils --- parasitic plants --- co-dispersal through space and time --- stable populations --- Coleoptera --- Curculionidae --- Curculioninae --- Acentrusini --- phylogeny --- Coleoptera --- Curculionidae --- Brachycerinae --- Tanysphyrini --- Afroryzophilus --- new species --- Afrotropical region --- Belidae --- Oxycoryninae --- Erotylidae --- Pharaxonothinae --- cycad pollination --- Alien --- invasive --- exotic --- biodiversity --- Patagonia --- Pinus radiata --- Eucalyptus --- taxonomy --- weevil --- new species --- Araucariaceae --- Hoop Pine --- Klinki Pine --- Australia --- Papuan region --- Neotropical region --- broad-nosed weevils --- Naupactini --- Pantomorus-Naupactus complex --- phylogeny --- COI --- combined evidence --- 1K Weevils Project --- biogeography --- classification --- Curculionidae --- Curculionoidea --- fossils --- Guillermo Kuschel --- morphology --- molecular phylogenetics --- DNA barcoding --- phylogeny --- phytophagy --- weevils --- Dichotrachelini --- systematics --- morphology --- evolution --- mt-Cox1 --- Cryptoplini --- taxonomy --- weevils --- tectal aedeagus --- Kuschelorhynchus --- Macadamia --- Syzygium --- Australia --- New Guinea --- Curculionidae --- biological control --- target host --- non-target host --- taxonomy --- phylogeny --- Sclerocardius --- Sclerocardiini --- taxonomy --- systematics --- elytro-tergal stridulation --- taxonomy --- identification --- diagnostics --- pollination --- flightlessness --- Curculionoidea --- weevil --- hygrophilous --- aquatic --- semi-aquatic --- riparian --- key --- Israel --- Curculionidae --- Anchonini --- Molytinae --- Aethiopacorep africanus --- neotype --- Titilayo --- Titilayo barclayi --- Titilayo garnerae --- Titilayo geiseri --- Titilayo takanoi --- Titilayo perrinae --- Titilayo saotomense --- Titilayo turneri --- taxonomy --- distribution --- taxonomy --- weevil --- new species --- Australia --- Papuan region --- Araceae --- biodiversity --- ecology --- faunal inventories --- mimicry --- phenology --- Brachycerinae --- Tanysphyrini --- Afroryzophilus --- new species --- Afrotropical region --- Cossoninae --- Rhyncolini --- Rhyncolina --- taxonomy --- new species --- Aciphylla --- Chatham Islands --- integrative taxonomy --- Poor Knights Islands --- weevils --- Urodontinae --- Urodontidius --- genitalia --- larva --- life history --- galling habit --- silk production --- taxonomy --- South Africa --- Namibia --- weevils --- new taxa --- Broad-nosed weevils --- Entiminae --- tribal relationships --- combined evidence --- ribosomal markers --- structural alignment --- mitochondrial COI --- adults --- larvae --- biography --- obituary --- weevils --- systematics --- publications --- Borneo --- tropical forest canopies --- fogging --- diversity --- forest disturbance --- weevil fauna --- longhorned beetle (Cerambycidae) --- new species --- Curculionoidea --- Mesophyletidae --- Cretaceous --- taxonomy --- morphology --- CT scanning --- amber preparation --- angiosperm associations --- weevil larvae --- palm weevils --- invasive species --- comparative morphology --- homonym --- taxonomy --- Curculionoidea --- Mesophyletidae --- Cretaceous

Molecular Computing and Bioinformatics

Authors: --- ---
ISBN: 9783039211951 / 9783039211968 Year: Pages: 390 DOI: 10.3390/books978-3-03921-196-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Biotechnology
Added to DOAB on : 2019-08-28 11:21:27
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Abstract

This text will provide the most recent knowledge and advances in the area of molecular computing and bioinformatics. Molecular computing and bioinformatics have a close relationship, paying attention to the same object but working towards different orientations. The articles will range from topics such as DNA computing and membrane computing to specific biomedical applications, including drug R&D and disease analysis.

Keywords

prostate cancer --- Mycoplasma hominis --- endoplasmic reticulum --- systems biology --- protein targeting --- biomedical text mining --- big data --- Tianhe-2 --- parallel computing --- load balancing --- bacterial computing --- bacteria and plasmid system --- Turing universality --- recursively enumerable function --- miRNA biogenesis --- structural patterns --- DCL1 --- protein–protein interaction (PPI) --- clustering --- protein complex --- penalized matrix decomposition --- avian influenza virus --- interspecies transmission --- amino acid mutation --- machine learning --- Bayesian causal model --- causal direction learning --- K2 --- brain storm optimization --- line graph --- Cartesian product graph --- join graph --- atom-bond connectivity index --- geometric arithmetic index --- P-glycoprotein --- efflux ratio --- in silico --- machine learning --- hierarchical support vector regression --- absorption --- distribution --- metabolism --- excretion --- toxicity --- image encryption --- chaotic map --- DNA coding --- Hamming distance --- Stenotrophomonas maltophilia --- iron acquisition systems --- iron-depleted --- RAST server --- NanoString Technologies --- siderophores --- gene fusion data --- gene susceptibility prioritization --- evaluating driver partner --- gene networks --- drug-target interaction prediction --- machine learning --- drug discovery --- microRNA --- environmental factor --- structure information --- similarity network --- bioinformatics --- identification of Chinese herbal medicines --- biochip technology --- DNA barcoding technology --- DNA strand displacement --- cascade --- 8-bit adder/subtractor --- domain label --- Alzheimer’s disease --- gene coding protein --- sequence information --- support vector machine --- classification --- adverse drug reaction prediction --- heterogeneous information network embedding --- stacking denoising auto-encoder --- meta-path-based proximity --- Panax ginseng --- oligopeptide transporter --- flowering plant --- phylogeny --- transcription factor --- multiple interaction networks --- function prediction --- multinetwork integration --- low-dimensional representation --- dihydrouridine --- nucleotide physicochemical property --- pseudo dinucleotide composition --- RNA secondary structure --- ensemble classifier --- diabetes mellitus --- hypoxia-inducible factor-1? --- angiogenesis --- bone formation --- osteogenesis --- protein transduction domain --- membrane computing --- edge detection --- enzymatic numerical P system --- resolution free --- molecular computing --- molecular learning --- DNA computing --- self-organizing systems --- pattern classification --- machine learning --- laccase --- Brassica napus --- lignification --- stress --- molecular computing --- bioinformatics --- machine learning --- protein --- DNA --- RNA --- drug --- bio-inspired

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