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Anticancer Drugs

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ISBN: 9783039215867 9783039215874 Year: Pages: 214 DOI: 10.3390/books978-3-03921-587-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:15
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The past decades have seen major developments in the understanding of the cellular and molecular biology of cancer. Significant progress has been achieved regarding long-term survival for the patients of many cancers with the use of tamoxifen for treatment of breast cancer, treatment of chronic myeloid leukaemia with imatinib, and the success of biological drugs. The transition from cytotoxic chemotherapy to targeted cancer drug discovery and development has resulted in an increasing selection of tools available to oncologists. In this Special Issue of Pharmaceuticals, we highlight the opportunities and challenges in the discovery and design of innovative cancer therapies, novel small-molecule cancer drugs and antibody–drug conjugates, with articles covering a variety of anticancer therapies and potential relevant disease states and applications. Significant efforts are being made to develop and improve cancer treatments and to translate basic research findings into clinical use, resulting in improvements in survival rates and quality of life for cancer patients. We demonstrate the possibilities and scope for future research in these areas and also highlight the challenges faced by scientists in the area of anticancer drug development leading to improved targeted treatments and better survival rates for cancer patients.

Advances in Experimental and Computational Rheology

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ISBN: 9783039213337 9783039213344 Year: Pages: 224 DOI: 10.3390/books978-3-03921-334-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General)
Added to DOAB on : 2019-12-09 16:10:12
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Rheology, defined as the science of deformation and flow of matter, is a multidisciplinary scientific field, covering both fundamental and applied approaches. The study of rheology includes both experimental and computational methods, which are not mutually exclusive. Its practical importance embraces many processes, from daily life, like preparing mayonnaise or spread an ointment or shampooing, to industrial processes like polymer processing and oil extraction, among several others. Practical applications include also formulations and product development. This Special Issue aims to present the latest advances in the fields of experimental and computational rheology applied to the most diverse classes of materials (foods, cosmetics, pharmaceuticals, polymers and biopolymers, multiphasic systems and composites) and processes. This Special Issue will comprise, not only original research papers, but also review articles.

Remote Sensing of Precipitation: Volume 1

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ISBN: 9783039212859 9783039212866 Year: Pages: 480 DOI: 10.3390/books978-3-03921-286-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Environmental Engineering
Added to DOAB on : 2019-08-28 11:21:27
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Precipitation is a well-recognized pillar in global water and energy balances. An accurate and timely understanding of its characteristics at the global, regional, and local scales is indispensable for a clearer understanding of the mechanisms underlying the Earth’s atmosphere–ocean complex system. Precipitation is one of the elements that is documented to be greatly affected by climate change. In its various forms, precipitation comprises a primary source of freshwater, which is vital for the sustainability of almost all human activities. Its socio-economic significance is fundamental in managing this natural resource effectively, in applications ranging from irrigation to industrial and household usage. Remote sensing of precipitation is pursued through a broad spectrum of continuously enriched and upgraded instrumentation, embracing sensors which can be ground-based (e.g., weather radars), satellite-borne (e.g., passive or active space-borne sensors), underwater (e.g., hydrophones), aerial, or ship-borne.

Keywords

GPM --- IMERG --- satellite precipitation adjustment --- numerical weather prediction --- heavy precipitation --- flood-inducing storm --- complex terrain --- precipitation --- geostationary microwave sensors --- polar systems --- synoptic weather types --- drop size distribution (DSD) --- microstructure of rain --- disdrometer --- radar reflectivity–rain rate relationship --- CHIRPS --- CMORPH --- TMPA --- MSWEP --- statistical evaluation --- VIC model --- hydrological simulation --- precipitation --- satellite --- GPM --- TRMM --- CFSR --- PERSIANN --- MSWEP --- streamflow simulation --- lumped models --- Peninsular Spain --- GPM IMERG v5 --- TRMM 3B42 v7 --- precipitation --- evaluation --- Huaihe River basin --- precipitation --- radar --- radiometer --- T-Matrix --- microwave scattering --- quantitative precipitation estimates --- validation --- PERSIANN-CCS --- meteorological radar --- satellite rainfall estimates --- satellite precipitation retrieval --- neural networks --- GPM --- GMI --- remote sensing --- hurricane Harvey --- GPM satellite --- IMERG --- tropical storm rainfall --- gridded radar precipitation --- precipitation --- satellites --- climate models --- regional climate models --- X-band radar --- dual-polarization --- precipitation --- complex terrain --- runoff simulations --- snowfall detection --- snow water path retrieval --- supercooled droplets detection --- GPM Microwave Imager --- Satellite Precipitation Estimates --- GPM --- TRMM --- IMERG --- GSMaP --- TMPA --- CMORPH --- assessment --- Pakistan --- heavy rainfall prediction --- satellite radiance --- data assimilation --- RMAPS --- harmonie model --- radar data assimilation --- pre-processing --- mesoscale precipitation patterns --- GNSS meteorology --- GPS --- Zenith Tropospheric Delay --- precipitable water vapor --- SEID --- single frequency GNSS --- Precise Point Positioning --- low-cost receivers --- goGPS --- GPM --- IMERG --- TRMM --- precipitation --- Cyprus --- satellite precipitation product --- Tianshan Mountains --- GPM --- TRMM --- CMORPH --- heavy precipitation --- rainfall retrieval techniques --- forecast model --- Red–Thai Binh River Basin --- TMPA 3B42V7 --- TMPA 3B42RT --- rainfall --- bias correction --- linear-scaling approach --- climatology --- topography --- precipitation --- remote sensing --- CloudSat --- CMIP --- high latitude --- mineral dust --- wet deposition --- cloud scavenging --- dust washout process --- Saharan dust transportation --- precipitation rate --- precipitating hydrometeor --- hydrometeor classification --- cloud radar --- Ka-band --- thunderstorm --- thundercloud --- vertical air velocity --- terminal velocity --- Milešovka observatory --- rain gauges --- radar --- quality indexes --- satellite rainfall retrievals --- validation --- surface rain intensity --- kriging with external drift --- PEMW --- MSG --- SEVIRI --- downscaling --- tropical cyclone --- rain rate --- precipitation --- remote sensing --- radiometer --- retrieval algorithm --- GPM --- DPR --- validation network --- volume matching --- reflectivity --- rainfall rate --- TRMM-era TMPA --- GPM-era IMERG --- satellite rainfall estimate --- Mainland China --- satellite precipitation --- Global Precipitation Measurement (GPM) --- IMERG --- TRMM-TMPA --- Ensemble Precipitation (EP) algorithm --- topographical and seasonal evaluation --- daily rainfall estimations --- TRMM 3B42 v7 --- rain gauges --- Amazon Basin --- regional rainfall regimes --- regional rainfall sub-regimes --- TRMM 3B42 V7 --- CMORPH_CRT --- PERSIANN_CDR --- GR models --- hydrological simulation --- Red River Basin --- satellite precipitation --- Tibetan Plateau --- GPM --- IMERG --- GSMaP --- precipitation --- weather --- radar --- GPM --- RADOLAN --- QPE --- TRMM --- TMPA --- 3B42 --- validation --- rainfall --- telemetric rain gauge --- Lai Nullah --- Pakistan --- XPOL radar --- GPM/IMERG --- WRF-Hydro --- CHAOS --- hydrometeorology --- flash flood --- Mandra --- typhoon --- IMERG --- GSMaP --- Southern China --- precipitation --- satellite remote sensing --- error analysis --- triple collocation --- precipitation --- TRMM --- GPM --- IMERG --- weather radar --- precipitable water vapor --- precipitation retrieval --- rain rate --- QPE

Remote Sensing of Precipitation: Volume 2

Author:
ISBN: 9783039212873 9783039212880 Year: Pages: 318 DOI: 10.3390/books978-3-03921-288-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Environmental Engineering
Added to DOAB on : 2019-08-28 11:21:27
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Abstract

Precipitation is a well-recognized pillar in global water and energy balances. An accurate and timely understanding of its characteristics at the global, regional, and local scales is indispensable for a clearer understanding of the mechanisms underlying the Earth’s atmosphere–ocean complex system. Precipitation is one of the elements that is documented to be greatly affected by climate change. In its various forms, precipitation comprises a primary source of freshwater, which is vital for the sustainability of almost all human activities. Its socio-economic significance is fundamental in managing this natural resource effectively, in applications ranging from irrigation to industrial and household usage. Remote sensing of precipitation is pursued through a broad spectrum of continuously enriched and upgraded instrumentation, embracing sensors which can be ground-based (e.g., weather radars), satellite-borne (e.g., passive or active space-borne sensors), underwater (e.g., hydrophones), aerial, or ship-borne.

Keywords

GPM --- IMERG --- satellite precipitation adjustment --- numerical weather prediction --- heavy precipitation --- flood-inducing storm --- complex terrain --- precipitation --- geostationary microwave sensors --- polar systems --- synoptic weather types --- drop size distribution (DSD) --- microstructure of rain --- disdrometer --- radar reflectivity–rain rate relationship --- CHIRPS --- CMORPH --- TMPA --- MSWEP --- statistical evaluation --- VIC model --- hydrological simulation --- precipitation --- satellite --- GPM --- TRMM --- CFSR --- PERSIANN --- MSWEP --- streamflow simulation --- lumped models --- Peninsular Spain --- GPM IMERG v5 --- TRMM 3B42 v7 --- precipitation --- evaluation --- Huaihe River basin --- precipitation --- radar --- radiometer --- T-Matrix --- microwave scattering --- quantitative precipitation estimates --- validation --- PERSIANN-CCS --- meteorological radar --- satellite rainfall estimates --- satellite precipitation retrieval --- neural networks --- GPM --- GMI --- remote sensing --- hurricane Harvey --- GPM satellite --- IMERG --- tropical storm rainfall --- gridded radar precipitation --- precipitation --- satellites --- climate models --- regional climate models --- X-band radar --- dual-polarization --- precipitation --- complex terrain --- runoff simulations --- snowfall detection --- snow water path retrieval --- supercooled droplets detection --- GPM Microwave Imager --- Satellite Precipitation Estimates --- GPM --- TRMM --- IMERG --- GSMaP --- TMPA --- CMORPH --- assessment --- Pakistan --- heavy rainfall prediction --- satellite radiance --- data assimilation --- RMAPS --- harmonie model --- radar data assimilation --- pre-processing --- mesoscale precipitation patterns --- GNSS meteorology --- GPS --- Zenith Tropospheric Delay --- precipitable water vapor --- SEID --- single frequency GNSS --- Precise Point Positioning --- low-cost receivers --- goGPS --- GPM --- IMERG --- TRMM --- precipitation --- Cyprus --- satellite precipitation product --- Tianshan Mountains --- GPM --- TRMM --- CMORPH --- heavy precipitation --- rainfall retrieval techniques --- forecast model --- Red–Thai Binh River Basin --- TMPA 3B42V7 --- TMPA 3B42RT --- rainfall --- bias correction --- linear-scaling approach --- climatology --- topography --- precipitation --- remote sensing --- CloudSat --- CMIP --- high latitude --- mineral dust --- wet deposition --- cloud scavenging --- dust washout process --- Saharan dust transportation --- precipitation rate --- precipitating hydrometeor --- hydrometeor classification --- cloud radar --- Ka-band --- thunderstorm --- thundercloud --- vertical air velocity --- terminal velocity --- Milešovka observatory --- rain gauges --- radar --- quality indexes --- satellite rainfall retrievals --- validation --- surface rain intensity --- kriging with external drift --- PEMW --- MSG --- SEVIRI --- downscaling --- tropical cyclone --- rain rate --- precipitation --- remote sensing --- radiometer --- retrieval algorithm --- GPM --- DPR --- validation network --- volume matching --- reflectivity --- rainfall rate --- TRMM-era TMPA --- GPM-era IMERG --- satellite rainfall estimate --- Mainland China --- satellite precipitation --- Global Precipitation Measurement (GPM) --- IMERG --- TRMM-TMPA --- Ensemble Precipitation (EP) algorithm --- topographical and seasonal evaluation --- daily rainfall estimations --- TRMM 3B42 v7 --- rain gauges --- Amazon Basin --- regional rainfall regimes --- regional rainfall sub-regimes --- TRMM 3B42 V7 --- CMORPH_CRT --- PERSIANN_CDR --- GR models --- hydrological simulation --- Red River Basin --- satellite precipitation --- Tibetan Plateau --- GPM --- IMERG --- GSMaP --- precipitation --- weather --- radar --- GPM --- RADOLAN --- QPE --- TRMM --- TMPA --- 3B42 --- validation --- rainfall --- telemetric rain gauge --- Lai Nullah --- Pakistan --- XPOL radar --- GPM/IMERG --- WRF-Hydro --- CHAOS --- hydrometeorology --- flash flood --- Mandra --- typhoon --- IMERG --- GSMaP --- Southern China --- precipitation --- satellite remote sensing --- error analysis --- triple collocation --- precipitation --- TRMM --- GPM --- IMERG --- weather radar --- precipitable water vapor --- precipitation retrieval --- rain rate --- QPE

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MDPI - Multidisciplinary Digital Publishing Institute (4)


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CC by-nc-nd (4)


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english (4)


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2019 (4)