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The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models

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ISBN: 9783319157917 9783319161044 Year: Pages: 338 DOI: 10.1007/978-3-319-16104-4 Language: English
Publisher: Springer Nature
Subject: Pharmacy and materia medica --- Physiology --- Microbiology --- Manufactures --- Biotechnology
Added to DOAB on : 2016-04-12 16:35:01
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'Infogest' (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (including food scientists, gut physiologists and nutritionists). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.

A Time for Metabolism and Hormones

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Book Series: Research and Perspectives in Endocrine Interactions ISSN: 1861-2253 ISBN: 9783319270685 9783319270692 Year: Pages: 132 DOI: 10.1007/978-3-319-27069-2 Language: English
Publisher: Springer Nature
Subject: Internal medicine
Added to DOAB on : 2016-12-20 11:46:51
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Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

High Density Lipoproteins: From Biological Understanding to Clinical Exploitation

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Book Series: Handbook of Experimental Pharmacology ISSN: 01712004 ISBN: 9783319096643 9783319096650 Year: Volume: 224 Pages: 694 DOI: 10.1007/978-3-319-09665-0 Language: English
Publisher: Springer Nature
Subject: Manufactures --- Electrical and Nuclear Engineering --- Chemical Technology --- Business and Management --- Biotechnology --- Therapeutics --- Medicine (General)
Added to DOAB on : 2015-07-20 15:18:00
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n this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation.The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.

Low-Dose Radiation Effects on Animals and Ecosystems

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ISBN: 9789811382185 Year: Pages: 264 DOI: 10.1007/978-981-13-8218-5 Language: English
Publisher: Springer Nature
Subject: Medicine (General) --- Mathematics --- Zoology --- Environmental Sciences
Added to DOAB on : 2020-02-04 11:21:23
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This open access book summarizes the latest scientific findings regarding the biological effects of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in 2011. Various cases of changes in animals and organisms have been reported since the FNPP accident. However, it is often unknown whether they are actually due to radiation, since the dose or dose-rate are not necessarily associated with the changes observed. This book brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem. Since the biological impact of radiation is influenced by various factors, it is difficult to scientifically define the effects of low-dose/low-dose-rate radiation. However, the detailed research data presented can be combined with the latest scientific and technological advances, such as artificial intelligence, to provide new insights in the future. This book is a unique and valuable resource for researchers, professionals and anyone interested in the impact of exposure to radiation or contamination with radioactive materials.

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