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Anhand der Entwicklung eines automatisierten Systems für die bidirektionale Kapillarelektrophorese (CE) im Chipformat wird der Einsatz der hauptsächlich in der Laboranalytik eingesetzten Chip-CE für den Bereich der kontinuierlichen Prozessanalytik gezeigt. Die Nutzung der Chip-CE sowie die simultane Analys von Kat- und Anionen führen zu einer deutlichen Verringerung herkömmlicher Analysezeiten. Die abschließende Messung gasförmiger und flüssiger Proben zeigt die Leistungsfähigkeit des Systems.

Lab-on-Chip, Kapillarelektrophorese, Mikrofluidik, Ionenanalyse, Prozessanalytik

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Microfluidics has developed rapidly over the past three decades. Relentless diagnostic, medical and chemical applications have been demonstrated in various applications, plateforms and tools. Have microfluidics realized its full potential? Or is it only a leveraging academic tool? In this Special Issue, we focus on both insights and advancements in microfluidics. We invite emerging investigators and pioneers to contribute commentaries, perspectives and insightful reviews on related topics. The various insights from esteemed colleagues will be collated. We will also discuss technological breakthrough of original works in both short communications and full papers. The main idea is to stimulate the community and to provide an unique collection of insightful papers. We will also cover various topics ranging from 3D printing, paper-based microfludics to conventional polymer-based microfluidics which contributes to the technological advancements.

Insights, Advancement, Perspective, Microfluidics, Lab on a chip, Development

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Diese Arbeit befasst sich mit neuen Aspekten der Nutzung der Klasse der organischen Halbleiterbauelemente. Es wird dabei insbesondere die Integration organischer Bauelemente in mikrooptische Systeme untersucht. Dabei stehen sowohl das Design, die Herstellung und die Charakterisierung als auch die Anwendung dieser Bauelemente in der Datenübertragung und Sensorik im Vordergrund.

OLED, OPD, PMMA, Lab-on-a-chip, Optical Interconnect

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The Prototype Laboratory initiated and maintained by the Chair of Product Development at the Faculty of Architecture, TU Delft, has set an example in architectural education for hands-on ‘learning-by-making’ for students. According to the authors of this book, in the current curriculums time spent on practical work is not rewarded and students are educated in an abstract concept of architecture, not getting a proper feeling for materialization. A semester of designing, engineering, producing and building a prototype with their own hands after their own design often gives students a boost in their education. The Delft Prototype laboratory was the base of around 1,000 students, now professionals. Some architect’s offices make prototypes regularly as their designs are quite experimental and require more insight for the designing architect, before the realization of his building. Prototypes of technical components are often developed parallel to the building process.The Prototype Laboratory at the Faculty of Architecture was supervised for almost 18 years by Peter van Swieten. He describes his experiences in this book, in collaboration with the initiator, professor Mick Eekhout. Marcel Bilow took over the Bucky Lab, as it is called, from 2012 onwards.

Prototype Laboratory --- TU Delft --- product development --- Bucky Lab --- design and build

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Biosensors are devices that utilize biological recognition elements to selectively detect and analyze specific biological and chemical analyte substances. In this work a technology platform for label-free optical biosensors based on surface-functionalized photonic crystal slabs is proposed. Using this technology platform, low-cost solutions for three biotechnical questions are presented.

photonic crystal, biosensor, lab-on-a-chip, contrast enhancement, affinity kinetics