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Advances in Prevention of Foodborne Pathogens of Public Health Concern during Manufacturing

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ISBN: 9783039219322 / 9783039219339 Year: Pages: 168 DOI: 10.3390/books978-3-03921-933-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-12-09 11:49:16
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Abstract

According to a report from the U.S. Centers for Disease Control and Prevention (CDC), achieving safe and healthier foods was one of the top ten achievements of public health in the 20th century. However, considerable persisting challenges currently exist in developed nations and developing economies for further assuring the safety and security of the food supplies. According to CDC estimates, as many as 3000 American adults, as an example, and based on a recent epidemiological estimate of the World Health Organization, around 420,000 individuals around the globe, lose their lives annually due to foodborne diseases. This emphasizes the need for innovative and emerging interventions, for further prevention or mitigation of the risk of foodborne microbial pathogens during food processing and manufacturing. The current publication discusses recent advancements and progress in the elimination and decontamination of microbial pathogens during various stages of manufacturing and production. Special emphasis is placed on hurdle validation studies, investigating decontamination of non-typhoidal Salmonella enterica serovars, various serogroups of Shiga toxin-producing Escherichia coli, public health-significant serotypes of Listeria monocytogenes, and pathogenic species of Cronobacter.

Biotechnological Applications of Phage and Phage-Derived Proteins

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ISBN: 9783039214419 / 9783039214426 Year: Pages: 236 DOI: 10.3390/books978-3-03921-442-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:15
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Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools have revealed innovative phage features and enabled new processes that can be further exploited for biotechnological applications in a wide variety of fields. The high-quality original articles and reviews presented in this Special Issue demonstrate the incredible potential of phages and their derived proteins in a wide range of biotechnological applications for human benefit. Considering the emergence of amazing new available bioengineering tools and the high abundance of phages and the multitude of phage proteins yet to be discovered and studied, we believe that the upcoming years will present us with many more fascinating and new previously unimagined phage-based biotechnological applications.

Keywords

gene expression regulation --- molecular probe --- macromolecular interactions --- phage-host interaction --- bacteriophage --- endolysin --- Clostridium perfringens --- alpha-sheet --- cancerous tumors --- capsid dynamics --- drug delivery vehicles --- native gel electrophoresis --- neurodegenerative disease --- pathogenic viruses --- phage display --- landscape phage --- major coat protein --- nanomedicine --- diagnostics --- biosensors --- M13 bacteriophage --- biofilm --- porous structure --- filters --- self-assembly --- T7phage library --- sarcoidosis --- tuberculosis --- microarray --- immunoscreening --- R-type pyocin --- bacteriocin --- contractile injection systems --- Pseudomonas aeruginosa --- X-ray crystallography --- receptor-binding protein --- Shigella flexneri --- bacteriophage --- tailspike proteins --- O-antigen --- serotyping --- microtiter plate assay --- fluorescence sensor --- bacteriophages --- encapsulation --- niosomes --- transfersomes --- liposomes --- Staphylococcus aureus --- phage --- Enterococcus faecalis --- Streptococcus agalactiae --- culture enrichment --- bacteriophage --- diagnostics --- Listeria monocytogenes --- endolysin --- magnetic separation --- reporter phage --- endolysin --- Pal --- Cpl-1 --- safety --- toxicity --- immune response --- Streptococcus pneumoniae --- self-assembly --- nanotubular structures --- tail sheath protein --- bacteriophage vB_EcoM_FV3 --- Appelmans --- bacteriophage evolution --- bacteriophage recombination --- phage therapy --- Pseudomonas aeruginosa --- antibiotic resistance --- bacteriophages --- Myoviridae --- bacteriophage-derived lytic enzyme --- enzybiotics --- endolysin --- in vitro activity --- ESKAPE --- n/a

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