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High-Resolution Neuroimaging - Basic Physical Principles and Clinical Applications

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ISBN: 9789535138655 9789535138662 9789535140450 Year: Pages: 174 DOI: 10.5772/intechopen.68268 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 07:51:51

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Dr. Ahmet Mesrur Halefoğlu mostly deals with research fields in body imaging and neuroradiology with multidetector computed tomography and high-resolution magnetic resonance imaging. He has served as postdoctoral research fellow at Johns Hopkins Hospital. Currently, he is working as an associate professor of radiology in Istanbul, Turkey. He has more than 50 high-impact-factor publications and has written 3 book chapters. He is a member of Turkish Society of Radiology and European Society of Radiology. During the recent years, there have been major breakthroughs in MRI due to developments in scanner technology and pulse sequencing. These important achievements have led to remarkable improvements in neuroimaging and advanced techniques, including diffusion imaging, diffusion tensor imaging, perfusion imaging, magnetic resonance spectroscopy, and functional MRI. These advanced neuroimaging techniques have enabled us to achieve invaluable insights into tissue microstructure, microvasculature, metabolism, and brain connectivity.

GABA And Glutamate - New Developments In Neurotransmission Research

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ISBN: 9789535138211 9789535138228 9789535140696 Year: Pages: 138 DOI: 10.5772/intechopen.68762 Language: English
Publisher: IntechOpen
Subject: Internal medicine
Added to DOAB on : 2019-10-03 07:51:51

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This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.

Alzheimer's Disease - The 21st Century Challenge

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ISBN: 9781789234626 9781789234633 Year: Pages: 162 DOI: 10.5772/intechopen.71628 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 07:51:51

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Alzheimer's disease was discovered over 100 years ago and still belongs to incurable neurological diseases; its pharmacotherapy is considered to be ineffective. This book presents contemporary views on the genetic, biochemical, and immunological determinants of this disease. This book also concerns the issue of Alzheimer's disease prevention through lifestyle and physical activity. Moreover, it describes the therapies used in Alzheimer's disease to slow the progression of the disease and delay its onset. Subsequently, the authors discuss experimental and clinical trials used now and in the near future. We hope that this book will help the readers to understand the complex mechanism leading to the development of Alzheimer's disease and indicate effective ways to prevent this disorder.

Prefrontal Cortex

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ISBN: 9781789239034 9781789239041 Year: Pages: 132 DOI: 10.5772/intechopen.73226 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 07:51:52

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The prefrontal cortex reaches its greatest development in the human brain, making up nearly one third of the neocortex. Due to its remarkable evolution, the prefrontal cortex plays an important role in higher integrative functions such as information processing, thinking, understanding, attention, behavior, motivation, emotions, working memory, and analysis. This book brings together theoretical and technical research advances on the prefrontal cortex, from the basic explanations of the neuronal architecture of the prefrontal cortex and its anatomy, presenting it as a morphological substrate for many psychological conditions, through normal and altered connectivity and its manifestation in different behavior and identification of organizational levels inside the prefrontal cortex through different neuroimaging methods. It also provides an interdisciplinary view of the prefrontal cortex and its issues and discovers the main role of this part of brain in psychosocial, economic, and cultural adaptation.

Cognitive and Computational Neuroscience - Principles, Algorithms and Applications

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ISBN: 9781789231885 9781789231892 Year: Pages: 104 DOI: 10.5772/intechopen.68377 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 09:47:13

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The book ""Cognitive and Computational Neuroscience - Principles, Algorithms and Applications"" will answer the following question and statements: System-level neural modeling: what and why? We know a lot about the brain! Need to integrate data: molecular/cellular/system levels. Complexity: need to abstract away higher-order principles. Models are tools to develop explicit theories, constrained by multiple levels (neural and behavioral). Key: models (should) make novel testable predictions on both neural and behavioral levels. Models are useful tools for guiding experiments. The hope is that the information provided in this book will trigger new researches that will help to connect basic neuroscience to clinical medicine.

Update on Dementia

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ISBN: 9789535126546 9789535126553 9789535141785 Year: Pages: 558 DOI: 10.5772/61983 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 07:51:49

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The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma and discrimination should be promoted. The common efforts and the final aim will have to be the progress of a ''dementia-constructive'' world, where people with dementia can take advantage of equal opportunities.

Mechanisms of Neuroinflammation

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ISBN: 9789535134510 9789535134527 Year: Pages: 318 DOI: 10.5772/66067 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 07:51:50

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""Mechanisms of Neuroinflammation"" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.

The Amygdala - A Discrete Multitasking Manager

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ISBN: 9789535109082 9789535142621 Year: Pages: 420 DOI: 10.5772/2973 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 09:47:09

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Among the components of the limbic system, the amygdala is a fascinating structure that is involved in the processes of liking and disliking and in the ways our emotions drive our actions and affect the strength of our memories. Combined with new conceptual breakthroughs, the very latest data obtained by leading world experts in amygdala function that are reviewed in this book have helped to understand how the amygdala contribute to these processes and also to a variety of neurological and neuropsychiatric pathologies. Of course, due to the rate of research advancement, all the chapters presented here correspond to precise questions addressed by experts using highly specific techniques. Therefore, each chapter should be viewed as pieces of a puzzle that represent all the different research areas that have to be taken into consideration in discussing the role of the amygdala in emotion and memory. Although the primary goal of this book is to inform experts and newcomers of some of the latest data in the field of brain structures involved in mechanisms underlying emotional learning and memory, we hope it will also help to stimulate discussion on the functional role of the amygdala and connected brain structures in these mechanisms.

Serotonin - A Chemical Messenger Between All Types of Living Cells

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ISBN: 9789535133612 9789535133629 Year: Pages: 316 DOI: 10.5772/65233 Language: English
Publisher: IntechOpen
Subject: Biochemistry --- Neurology
Added to DOAB on : 2019-10-03 07:51:50

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Serotonin - A Chemical Messenger Between All Types of Living Cells is a very interesting book on the most ancient neurotransmitter, hormone and trophic factor serotonin or 5-hydroxytryptamine (5-HT). This unique chemical is present in all living cells including plants and animals. This book will take us through a serene journey of the evolutionary history of serotonin and its role from man to mollusk. There are many interesting chapters incorporated in this book, including novel approaches for detecting minor metabolites of serotonin in human plasma, production and function of serotonin in cardiac cells, immuno-thrombotic effects of serotonin in platelets to the identification and localization of serotonin in the nervous system and gonad of bivalve mollusks.

Recent Advances in Cannabinoid Research

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ISBN: 9781838801519 9781838801526 9781838806415 Year: Pages: 230 DOI: 10.5772/intechopen.73801 Language: English
Publisher: IntechOpen
Subject: Biochemistry --- Neurology
Added to DOAB on : 2019-10-03 07:51:53

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Scientific interest in cannabinoid research is currently experiencing a significant increase because of changing attitudes toward Cannabis and the evolving awareness of its pharmaceutical benefits. Coincidently, numerous jurisdictions are moving toward legalizing Cannabis and Cannabis-derived products, which reflects a larger global movement to understand Cannabis and its bioactive chemicals for their potential biomedical uses, harms, and economic value. Research activities are surging to fill important knowledge gaps in the field of cannabinoids as they continue to be identified. The purpose of this book is to summarize some leading areas of research in the cannabinoid field where knowledge gaps are actively being addressed. The research described herein spans basic biological and clinical research.

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