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Kommunikationstechnische Optimierung eines energieautarken funkbasierten Sensorkonzepts

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ISBN: 9783966270069 9783966270076 9783966270045 9783966270052 Year: Pages: 94 DOI: 10.33968/9783966270069-00 Language: German
Publisher: HTWK Leipzig - OA-Hochschulverlag
Subject: Agriculture (General)
Added to DOAB on : 2019-10-21 11:21:20
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In this bachelor thesis, an existing wireless sensor concept was examined with regard to software optimization possibilities. First, the application possibilities of such sensor systems in the existing maintenance strategies were described. Subsequently, an analysis of the previous sensor concept was carried out, on the basis of which an alternative concept to communication optimisation was realised with the existing hardware. By replacing the previously used application protocol HTTP with the lightweight MQTT, an alternative sensor concept was created. In addition, a measurement concept was developed to determine the transmission time, which allows a comparison with the existing sensor concept. It was thus possible to evaluate the extent to which the objective had been achieved.

Analyse von Kundenaktivitäten und der Bereitstellungsqualität von Büchern aus Kundensicht

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ISBN: 9783966270106 9783966210113 9783966270083 9783966270090 9783966270113 Year: Pages: 160 DOI: 10.33968/9783966270106-00 Language: German
Publisher: HTWK Leipzig - OA-Hochschulverlag
Subject: Media and communication
Added to DOAB on : 2019-12-20 11:21:02
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"This master thesis explores service characteristics that are relevant for book readers when they evaluate a service as well as starting points for providers when they plan to optimize their services from a customer’s point of view.
In the first part ways of accessing books (buying, borrowing, rent) and the reading behavior of Germans will be described. Then the concept “quality of provision” of books will be discussed which distinguishes five quality dimensions of a service: diversity of content and arranging of books, basic technology (printed book or digital environment), temporal and spatial access, costs of access and ease of use.
By using secondary material for each dimension individual quality characteristics will be identified. Next the theoretical background of the activity theory and a special way of thinking, the customer-dominant-logic, from the Nordic school will be explained briefly. Based on this a set of consumer activities related to books will be presented and some activities that are relevant for the work will be described in more detail by means of secondary material (reading books, choosing books, organizing books and information). Further customization and personalization will be proposed as strategies for individualization of services and their function for consumers will be explained. The secondary data used in the work comes from empirical data out of consumer surveys in libraries and bookshops, nationally representative surveys and from results of academic research from different fields. In the final part of this thesis an own data collection will be conducted by using a content analysis of consumer comments of two e-book rental apps (n = 1,245 comments). The analysis should clarify, if the quality characteristics, the book-related activities and the strategies for individualization described before can be found in everyday reality of consumers. After that the results of the content analysis will be presented. Finally the major findings will be summarized and connected to the research questions."

Stadt als Schule

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ISBN: 9783966270144 9783966270120 Year: Pages: 68 DOI: 10.33968/9783966270144-00 Language: German
Publisher: HTWK Leipzig - OA-Hochschulverlag
Subject: Architecture
Added to DOAB on : 2019-10-21 11:21:20
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When a fire department called "Ostwache" in the eastern part of Leipzig closed down, it left their old building behind vacant. Soon after a neighbourhood initiative sought to use the space to establish a community center for the surrounding neighbourhood. At the same time, the municipal government was planning a new school on the same lot. This thesis presents a solution for this conflict. By bringing together architectural, urban planning and pedagogical perspectives, while aiming for synergies. Following the model of Freinet pedagogy, a community school was planned with a new building at the site of the old fire station and the community center is to be located in the existing building of the old Ostwache. Through a common courtyard, shared work and sports facilities and a shared lunch, the school opens up to the city and its neighborhood to the school. This is how city works as school and a school works as city.

Research of Pathogenesis and Novel Therapeutics in Arthritis

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ISBN: 9783038970651 / 9783038970668 Year: Pages: 366 DOI: 10.3390/books978-3-03897-066-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-06-26 08:44:06
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Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.

Keywords

biosimilars --- Th9 lymphocytes --- rheumatoid arthritis --- infliximab --- rheumatoid arthritis --- bone erosion --- osteoblasts --- next-generation sequencing --- bioinformatics --- microRNA --- messenger RNA --- osteoarthritis --- cell signaling --- IL1? --- WNT --- antagonists --- computational modeling --- nitric oxide --- clodronate --- gene expression --- osteoarthritis --- progenitor cells --- SOX9 --- spondyloarthropathies --- inflammation --- mesenchymal stem cells --- visfatin --- IL-6 --- TNF-? --- osteoarthritis --- miR-199a-5p --- Epstein-Barr virus --- glycoprotein 42 --- rheumatoid arthritis --- shared epitope --- triptolide --- rheumatoid arthritis --- basic research --- clinical translation --- osteoarthritis (OA) --- articular cartilage --- molecular pathology --- therapeutics --- rheumatoid arthritis --- antibodies --- collagen --- glycosylation --- disease pathways --- therapy --- experimental arthritis --- TNF? --- etanercept --- infliximab --- adalimumab --- certolizumab pegol --- golimumab --- rheumatoid arthritis --- therapeutic antibody --- structure --- fraxinellone --- collagen-induced arthritis --- rheumatoid arthritis --- inflammatory arthritis --- osteoclastogenesis --- sclareol --- rheumatoid arthritis --- synovial cell --- collagen --- mice --- cytokines --- Th17 --- MAPK --- arthritis --- osteoarthritis --- rheumatoid arthritis --- small-molecule inhibitor --- chondrocytes --- tumor necrosis factor-alpha --- inflammation --- rheumatoid arthritis --- osteoarthritis --- angiogenesis --- cytokines --- chemokines --- early osteoarthritis --- articular cartilage --- proliferation --- fibroblast growth factor 2 --- mitogen activated protein kinase --- transforming growth factor ? --- SMA- and MAD-related protein --- interleukin --- nuclear factor kappa B --- miRNA --- adjuvant arthritis --- arthritis --- biomarkers --- celastrol --- inflammation --- microRNA --- miRNA --- rat --- rheumatoid arthritis --- Traditional Chinese medicine --- tripterine --- triterpenoid --- spinal fusion --- biological --- osteoblast --- osteoclast --- bisphosphonate --- parathyroid hormone --- bone morphogenetic protein --- receptor activator of nuclear factor ?B --- stem cell --- drug delivery system --- anticitrullinated peptide antibodies --- antirheumatic drug --- autoimmune --- disease-modifying --- immunology --- pathology --- rheumatoid factor --- rheumatoid arthritis --- osteoarthritis --- adipokines --- obesity --- rheumatoid arthritis --- osteoarthritis --- anti-arthritis --- biomarkers

Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts

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ISBN: 9783039213634 / 9783039213641 Year: Pages: 376 DOI: 10.3390/books978-3-03921-364-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Public Health
Added to DOAB on : 2019-12-09 11:49:15
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Several species of Dinophysis produce one or two groups of lipophilic toxins: okadaic acid (OA) and its derivatives; or the dinophysistoxins (DTXs) (also known as diarrhetic shellfish poisons or DSP toxins) and pectenotoxins (PTXs). DSP toxins are potent inhibitors of protein phosphatases, causing gastrointestinal intoxication in consumers of contaminated seafood. Forty years after the identification of Dinophysis as the causative agent of DSP in Japan, contamination of filter feeding shellfish exposed to Dinophysis blooms is recognized as a problem worldwide. DSP events affect public health and cause considerable losses to the shellfish industry. Costly monitoring programs are implemented in regions with relevant shellfish production to prevent these socioeconomic impacts. Harvest closures are enforced whenever toxin levels exceed regulatory limits (RLs). Dinophysis species are kleptoplastidic dinoflagellates; they feed on ciliates (Mesodinium genus) that have previously acquired plastids from cryptophycean (genera Teleaulax, Plagioselmis, and Geminigera) nanoflagellates. The interactions of Dinophysis with different prey regulate their growth and toxin production. When Dinophysis cells are ingested by shellfish, their toxins are partially biotransformed and bioaccumulated, rendering the shellfish unsuitable for human consumption. DSP toxins may also affect shellfish metabolism. This book covers diverse aspects of the abovementioned topics—from the laboratory culture of Dinophysis and the kinetics of uptake, transformation, and depuration of DSP toxins in shellfish to Dinophysis population dynamics, the monitoring and regulation of DSP toxins, and their impact on the shellfish industry in some of the aquaculture regions that are traditionally most affected, namely, northeastern Japan, western Europe, southern Chile, and New Zealand.

Keywords

harmful algal bloom --- Diarrheic Shellfish Poisoning --- okadaic acid --- toxin accumulation --- toxin vectors --- trophic transfer --- Brazil --- diarrhetic shellfish toxins (DST) --- Mytilus galloprovincialis --- DST accumulation --- DST esterification --- suspended particulate matter (SPM) --- harmful algal blooms --- okadaic acid --- Argopecten irradians --- transcriptomic response --- deep sequencing --- pectenotoxins --- surf clam --- accumulation --- biotransformation --- depuration --- diarrhetic shellfish toxins --- accumulation --- dinophysistoxin --- Japanese scallop --- dinophysis --- LC/MS/MS --- statistical analysis --- Dinophysis --- HAB monitoring --- DSP toxins --- aquaculture --- shellfish toxicity --- human health --- time-series --- seasonality --- Scotland --- DSP toxins --- bivalves --- mussel --- resistance --- RNA-Seq --- qPCR --- metabolism --- defense --- immunity --- DSP toxins --- pectenotoxins --- Dinophysis acuminata --- Mesodinium rubrum --- bacterial community --- high throughput sequencing --- diarrhetic shellfish toxins --- Dinophysis --- wild harvest --- bivalve shellfish --- pipis (Plebidonax deltoides) --- Sydney rock oyster (Saccostrea glomerata) --- okadaic acid --- pectenotoxins --- Dinophysis toxins --- accumulation --- digestion --- biotransformation --- compartmentalization --- depuration --- kinetics --- Dinophysis --- diarrhetic shellfish poisoning --- marine toxins --- pectenotoxin --- okadaic acid --- dinophysistoxin --- okadaic acid --- pectenotoxins --- Dinophysis --- D. acuminata-complex --- D. caudata --- Argopecten purpuratus --- Dinophysis --- Mesodinium --- cryptophytes --- predator-prey preferences --- Diarrhetic Shellfish Toxins (DST) --- pectenotoxins (PTXs) --- mixotrophic cultures --- mass culture conditions --- Dinophysis acuminata --- Protoceratium reticulatum --- Reloncaví Fjord --- OMI analysis --- WitOMI analysis --- Mesodinium cf. rubrum --- El Niño Southern Oscillation --- Southern Annual Mode --- Dinophysis acuta --- Dinophysis acuminata --- DSP --- physical–biological interactions --- niche partitioning --- climatic anomaly --- Dinophysis acuminata --- Mesodinium rubrum --- lysate --- organic matter --- diarrhetic shellfish poisoning --- okadaic acid --- dinophysistoxin --- pectenotoxins --- dinophysis --- DSP --- toxins --- OA --- DTX-2 --- PTXs --- Dinophysis acuminata --- dinophysistoxins --- pectenotoxins --- Port Underwood --- New Zealand --- Dinophysis --- Diarrhetic shellfish toxins --- marine biotoxins --- blooms --- n/a

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