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Diseases of the Abdomen and Pelvis 2018-2021: Diagnostic Imaging - IDKD Book

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Book Series: IDKD Springer Series ISSN: 2523-7829 ISBN: 9783319750187 9783319750194 Year: Pages: 264 DOI: https://doi.org/10.1007/978-3-319-75019-4 Language: English
Publisher: Springer Nature Grant: Foundation for the Advancement of Education in Medical Radiology
Subject: Internal medicine
Added to DOAB on : 2018-06-22 17:34:01
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Abstract

This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

Keywords

Gastrointestinal disease --- PET/CT --- Radiology --- X-ray --- IDKD --- Davos

Atherosclerosis and Vascular Imaging

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ISBN: 9783038424352 9783038424345 Year: Pages: VIII, 164 DOI: 10.3390/books978-3-03842-435-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2017-06-27 09:23:42
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Cardiovascular disease is the main cause of death in the West, and vascular disease is the most common cardiovascular clinical problem. The disease results in serious morbidity and mortality, and carries economic cost implications. While conventional risk factors are well established, and their biomarkers regularly monitored, patients may continue to suffer subclinical active disease, even in the absence of risk factors, until they present with sudden cardiac death or stroke. Early disease detection using direct imaging has shown to be more accurate in identifying vulnerable patients and unstable plaques than conventional risk factors. This IJMS issue deals with the current opinion concerning the state-of-the-art imaging technologies available for clinical applications and their unique value over the sole use of conventional risk factor analysis, in identifying vulnerable patients, recommending aggressive treatments, prognosticating, and in assessing related nutritional and environmental issues.

Atherosclerosis and Vascular Imaging 2016

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ISBN: 9783038424321 9783038424338 Year: Pages: VIII, 182 DOI: 10.3390/books978-3-03842-433-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2017-06-27 09:38:14
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Cardiovascular disease is the main cause of death in the West, and vascular disease is the most common cardiovascular clinical problem. The disease results in serious morbidity and mortality, and carries economic cost implications. While conventional risk factors are well established, and their biomarkers regularly monitored, patients may continue to suffer subclinical active disease, even in the absence of risk factors, until they present with sudden cardiac death or stroke. Early disease detection using direct imaging has shown to be more accurate in identifying vulnerable patients and unstable plaques than conventional risk factors. This IJMS Special Issue deals with the current opinion concerning the state-of-the-art imaging technologies available for clinical applications, and their unique value over the sole use of conventional risk factor analysis, in identifying vulnerable patients, recommending aggressive treatments, prognosticating, and in assessing related nutritional and environmental issues. This Special Issue is the continuation of our 2015 Special Issue “Atherosclerosis and Vascular Imaging”

Anticancer Drugs

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ISBN: 9783039215867 9783039215874 Year: Pages: 214 DOI: 10.3390/books978-3-03921-587-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:15
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The past decades have seen major developments in the understanding of the cellular and molecular biology of cancer. Significant progress has been achieved regarding long-term survival for the patients of many cancers with the use of tamoxifen for treatment of breast cancer, treatment of chronic myeloid leukaemia with imatinib, and the success of biological drugs. The transition from cytotoxic chemotherapy to targeted cancer drug discovery and development has resulted in an increasing selection of tools available to oncologists. In this Special Issue of Pharmaceuticals, we highlight the opportunities and challenges in the discovery and design of innovative cancer therapies, novel small-molecule cancer drugs and antibody–drug conjugates, with articles covering a variety of anticancer therapies and potential relevant disease states and applications. Significant efforts are being made to develop and improve cancer treatments and to translate basic research findings into clinical use, resulting in improvements in survival rates and quality of life for cancer patients. We demonstrate the possibilities and scope for future research in these areas and also highlight the challenges faced by scientists in the area of anticancer drug development leading to improved targeted treatments and better survival rates for cancer patients.

Targets, Tracers and Translation – Novel Radiopharmaceuticals Boost Nuclear Medicine

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ISBN: 9783039213139 9783039213146 Year: Pages: 214 DOI: 10.3390/books978-3-03921-314-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-12-09 11:49:15
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This is the fourth Special Issue in Pharmaceuticals within the last six years dealing with aspects of radiopharmaceutical sciences. It demonstrates the significant interest and increasing relevance to ameliorate nuclear medicine imaging with PET or SPECT, and also radiotherapeutical procedures.Numerous targets and mechanisms have been identified and have been under investigation over the previous years, covering many fields of medical and clinical research. This development is well illustrated by the articles in the present issue, including 13 original research papers and one review, covering a broad range of actual research topics in the field of radiopharmaceutical sciences.

Keywords

breast cancer --- 68Ga --- GRPR --- NPY(Y1)R --- peptide heterodimers --- PET/CT imaging --- sentinel lymph node --- dextran --- mannose --- 99mTc-radiopharmaceuticals --- glutamate --- metabotropic glutamate receptor subtype 5 --- [18F]PSS232 --- ketamine --- ceftriaxone --- positron emission tomography --- allosteric modulator --- MMPEP --- ABP688 --- pretargeting --- Fusarinine C --- rituximab --- click chemistry --- multimerization --- PET --- gallium-68 --- carbonic anhydrase IX --- girentuximab --- renal cell carcinomas --- 177Lu-radiopharmaceuticals --- radioimmunotherapy --- neuroinflammation --- microglia --- carbon-11 --- radiochemistry --- positron emission tomography --- hypoxia --- radiosensitizer --- benzotriazine-1,4-dioxide (BTDO), benzotriazine-1-monoxide (BTMO), tirapazamine (TPZ), SR 4317 --- radioiodination --- tropomyosin receptor kinase --- positron emission tomography --- neurodegeneration --- oncogenic fusions --- [11C]meta-hydroxyephedrine --- radiosynthesis --- separation --- apparent molar activity --- cholecystokinin-2 receptor --- minigastrin --- molecular imaging --- radiometals --- technetium-99m --- hydrazinonicotinic acid (HYNIC) --- PSMA-617 --- salivary gland uptake --- prostate cancer --- endoradiotherapy --- Chloramine T --- electrophilic radioiodination --- iodine-131 --- Iodo-Gen® --- oxidizing agent --- ?-CIT. --- tumor hypoxia --- PET --- small animal imaging --- azomycin nucleosides --- [18F]FMISO --- bombesin --- gastrin-releasing peptide --- gastrin-releasing peptide receptor --- tumor targeting --- 99mTc-radioligand --- metabolic stability --- neprilysin-inhibition --- phosphoramidon --- n/a --- n/a

Pheochromocytoma (PHEO) and Paraganglioma (PGL)

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ISBN: 9783039216543 9783039216550 Year: Pages: 380 DOI: 10.3390/books978-3-03921-655-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2019-12-09 11:49:16
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This book outlines some new advances in genetics, clinical evaluation, localization, therapy (newly including immunotherapy) of pheochromocytoma and paraganglioma including their metastatic counterparts. Well-known and experienced clinicians and scientists contributed to this book to include some novel approaches to these tumors. This book will serve to various health care professionals from different subspecialties, but mainly oncologists, endocrinologists, endocrine surgeons, pediatricians, and radiologists. This book shows that the field of pheochromocytoma/paraganglioma is evolving and a significant progress has been made in last 5 years requiring that health care professionals and scientists will learns new information and implement it in their clinical practice or scientific work, respectively. This book should not be missed by anybody who is focusing on neuroendocrine tumors, their newest evaluation and treatment.

Keywords

pheochromocytoma --- paraganglioma --- adrenocortical carcinoma --- adrenal tumor --- pan-cancer analysis --- neural crest --- neuroendocrine --- paraganglioma --- head and neck --- radiotherapy --- 18F-FDOPA --- PET --- GTV --- SDHB --- SDHD --- mortality --- paraganglioma --- pheochromocytoma --- radiofrequency ablation --- cryoablation --- percutaneous ethanol injection --- neuroendocrine tumor --- minimally invasive procedure --- percutaneous ablation --- PASS --- GAPP --- histology --- meta-analysis --- paraganglioma --- pheochromocytoma --- carotid body --- angiogenesis --- mitochondria --- neural crest --- neurogenesis --- paraganglioma --- stem-like tumor cells --- vasculogenesis --- xenograft --- pheochromocytoma --- catecholamine --- global longitudinal strain --- speckle-tracking echocardiography --- subclinical systolic dysfunction --- pheochromocytoma --- paraganglioma --- neuroendocrine tumor --- targeted therapy --- therapy resistance --- FGF21 --- pheochromocytoma --- paraganglioma --- diabetes mellitus --- obesity --- energy metabolism --- calorimetry --- chromogranin A --- metanephrines --- pheochromocytoma --- paraganglioma --- hypoxia --- pseudohypoxia --- spheroids --- HIF --- EPAS1 --- catecholamine --- pheochromocytoma and paraganglioma --- phosphorylation tyrosine hydroxylase --- dog --- pheochromocytoma --- paraganglioma --- SDHB --- SDHD --- mutation --- chromosomal alteration --- comparative genomics --- pheochromocytoma --- paraganglioma --- metastatic --- immunotherapy --- innate immunity --- adaptive immunity --- toll-like receptor --- pathogen-associated molecular patterns --- neutrophil --- T cell --- pheochromocytoma --- paraganglioma --- hypertension --- blood pressure variability --- average real variability --- weighted standard deviation --- paraganglioma --- somatostatinoma --- polycythemia --- EPAS1 --- transgenic mice --- erythropoietin --- pheochromocytoma --- paraganglioma --- TCA cycle --- germline mutation --- metastatic OR malignant pheochromocytoma --- paraganglioma --- ectopic secretion --- lL-6 --- normetanephrines --- VHL --- NF1 --- EPAS1 --- hypoxia-inducible factor --- inflammation --- radiosensitization --- succinate dehydrogenase --- mouse pheochromocytoma cells --- immunohistochemistry --- fluorescence imaging --- pheochromocytoma --- paraganglioma --- next-generation sequencing --- sporadic --- hereditary --- CNV detection --- pheochromocytoma --- paraganglioma --- PET-CT --- 11C-hydroxy-ephedrine --- adrenal incidentaloma --- pheochromocytoma --- paraganglioma --- 177Lu-DOTATATE --- peptide receptor radiotherapy --- PRRT --- neuroendocrine tumor --- NET --- PCC --- PGL --- postoperative --- pheochromocytoma --- hypertension --- hypotension --- arrhythmia --- PPGL --- catecholamines --- adrenomedullary function --- n/a

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