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Terrestrial plants are sessile organisms that, differently from animals, can not move in searching of the nutrients and water they need. Instead, they have to change continuously their physiology and morphology to adapt to the environmental changes. When plants suffer from a nutrient deficiency, they develop physiological and morphological responses (mainly in their roots) aimed to facilitate the acquisition and mobilization of such a nutrient. Physiological responses include some ones like acidification of the rizhosphere and release of chelating agents into the medium; and morphological responses include others, like changes in root architecture and development of root hairs. The regulation of these responses is not totally known but in the last years different plant hormones and signaling substances, such as auxin, ethylene, cytokinins and nitric oxide, have been involved in their control. Besides hormones, oxidative stress has also been related with most of the nutrient deficiencies. The relationship of ethylene with the regulation of responses to nutrient deficiencies came from the nineties, when some works presented data suggesting its involvement in the regulation of responses to Fe and P deficiency. In the last years, the role of ethylene has been extended to many other nutrient deficiencies, such as K deficiency, Mg deficiency, S deficiency, N deficiency, and others. In most of the cases, it has been found that ethylene production, as well as the expression of ethylene synthesis genes, increases under these nutrient deficiencies. Furthermore, it has also been found that ethylene controls the expression of genes related to responses to different deficiencies. The involvement of ethylene in so many deficiencies suggests that it should act in conjunction with other signals that would confer nutrient-specificity to the distinct nutrient responses. These other signals could be plant hormones (auxin, cytokinins, etc) as well as other substances (nitric oxide, microRNAs, peptides, glutathione, etc), either originated in the roots or coming from the shoots through the phloem. The role of ethylene in the mineral nutrition of plants is even more complex that the one related to its role in the responses to nutrient deficiencies. Ethylene has also been implicated in the N2 fixation of legume plants; in salt tolerance responses; and in responses to heavy metals, such as Cd toxicity. All these processes are related to ion uptake and, consequently, are related to plant mineral nutrition. We consider a good opportunity to review all this information in a coordinated way. This Research Topic will provide an overview about the role of the plant hormone ethylene on the regulation of physiological and morphological responses to different nutrient deficiencies. In addition, it will cover other aspects of ethylene related to plant nutrition such as its role on salinity, N2 fixation and tolerance to heavy metals.
Boron --- ethylene --- heavy metals --- Iron --- Nitrogen --- nodulation --- Phosphate --- Potassium --- Salinity --- Sulfur
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Obesity and its co-morbidities, including atherosclerosis, insulin resistance and diabetes, are a world-wide epidemic. Inflammatory immune responses in metabolic tissues have emerged as a universal feature of these metabolic disorders. While initial work highlighted the contribution of macrophages to tissue inflammation and insulin resistance, recent studies demonstrate that cells of the adaptive immune compartment, including T and B lymphocytes and dendritic cells also participate in obesity-induced pathogenesis of these conditions. However, the molecular and cellular pathways by which the innate and adaptive branches of immunity control tissue and systemic metabolism remain poorly understood. To engage in growth and activation, cells need to increase their biomass and replicate their genome. This process presents a substantial bioenergetic challenge: growing and activated cells must increase ATP production and acquire or synthesize raw materials, including lipids, proteins and nucleic acids. To do so, they actively reprogram their intracellular metabolism from catabolic mitochondrial oxidative phosphorylation to glycolysis and other anabolic pathways. This metabolic reprogramming is under the control of specific signal transduction pathways whose underlying molecular mechanisms and relevance to physiology and disease are subject of considerable current interest and under intense study. Recent reports have elucidated the physiological role of metabolic reprogramming in macrophage and T cell activation and differentiation, B- and dendritic cell biology, as well as in the crosstalk of immune cells with endothelial and stem cells. It is also becoming increasingly evident that alterations of metabolic pathways play a major role in the pathogenesis of chronic inflammatory disorders. Due to the scientific distance between immunologists and experts in metabolism (e.g., clinicians and biochemists), however, there has been limited cross-talk between these communities. This collection of articles aims at promoting such cross-talk and accelerating discoveries in the emerging field of immunometabolism.
Glycolysis --- Pentose Phosphate Pathway --- TCA cycle --- fatty acid oxidation --- Inflammation --- Obesity --- metabolic syndrome --- Immunometabolism --- lymphocyte --- macrophage
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This book focus principally on ions-releasing and other smart dental materials for application in preventive and restorative dentistry, as well as in endodontics in the form of adhesives, resin-based composites, pastes, varnishes, liners and dental cements. Special attention has been given to bioactive materials developed to induce cells differentiation/stimulation, hard tissue formation and exert antimicrobial actions. New innovations are necessary to continue to help reinforcing existing technologies and to introduce new paradigms for treating dental disease and restoring teeth seriously compromised by caries lesions via biomimetic and more biological operative approaches. Dental bioactive materials is arguably the latest research area in dentistry and thus the amount of new research is overwhelming. However, in this day and age of evidence based practice it important for this new information to be distilled into a practical and understandable format.
orthodontic resin --- photocatalyst TiO2 --- antibacterial --- cariogenic --- early colonizer --- hydrophilic properties --- irradiation --- calcium silicate cements --- pulpal response --- mineralization --- calcific barrier --- inflammation --- odontoblastic layer --- resin cements --- shrinkage stress --- water sorption --- hydroscopic expansion --- photoelastic investigation --- antibacterial --- calcium --- doxycycline --- nanoparticles --- zinc --- dental composites --- antibacterial properties --- silver --- mechanical properties --- degree of conversion --- sorption --- solubility --- color stability --- mechanical properties --- nanotubes --- resin composite --- Streptococcus mutans --- triclosan --- bleaching products --- diffusion --- cytotoxicity --- dental pulp --- stem cells --- nanoporous silica --- glass-ionomer cement --- calcium --- preclinical biosafety --- bone substitute --- mesenchymal stem cells --- ?-tricalcium phosphate --- tissue engineering --- dental sealant --- resin sealant --- calcium phosphate nanoparticles --- long-term ion release --- remineralization --- ion recharge --- dentin --- desmineralization --- microtensile bond strength --- adhesion --- bioactive --- cycling mechanical stress --- dentine --- longevity --- resin-modified glass ionomer cements --- polyacrylic acid treatment --- bone regeneration --- ?-tricalcium phosphate --- calcium sulfate --- bone substitutes --- animal study --- n/a --- adhesion --- cycling mechanical stress --- dentine --- longevity --- glass-ionomer cements --- universal adhesives
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Reactions at mineral surfaces are central to all geochemical processes. As minerals comprise the rocks of the Earth, the processes occurring at the mineral–aqueous fluid interface control the evolution of the rocks and hence the structure of the crust of the Earth during processes such as metamorphism, metasomatism, and weathering. In recent years focus has been concentrated on mineral surface reactions made possible through the development of advanced analytical methods such as atomic force microscopy (AFM), advanced electron microscopies (SEM and TEM), phase shift interferometry, confocal Raman spectroscopy, and advanced synchrotron-based applications, to enable mineral surfaces to be imaged and analyzed at the nanoscale. Experiments are increasingly complemented by molecular simulations to confirm or predict the results of these studies. This has enabled new and exciting possibilities to elucidate the mechanisms that govern mineral–fluid reactions. In this Special Issue, “Mineral Surface Reactions at the Nanoscale”, we present 12 contributions that highlight the role and importance of mineral surfaces in varying fields of research.
Raman spectroscopy --- mineralogy --- replacement reaction --- isotopes --- additives --- biomineralisation --- classical nucleation theory --- interfaces --- liquid precursors --- minerals --- mesocrystals --- non-classical nucleation --- pre-nucleation clusters --- polymorphs --- interfacial precipitation --- phosphate --- hematite --- goethite --- dissolution-precipitation --- citrate --- carbonation --- wollastonite --- catalysts --- carbonic anhydrase --- MOFs --- carbon capture and storage --- albite --- amorphous --- analcime --- dissolution–precipitation --- hydrothermal experiments --- metasomatism --- nepheline --- sodalite --- calcite --- surface --- kinetics --- rate spectra --- retreat velocity --- dissolution --- bioaragonite --- apatite --- microstructure --- dissolution-reprecipitation --- mineral replacement --- brushite --- mineral growth --- calcium phosphate --- adsorption --- simulation --- metadynamics --- dissolution–precipitation --- toxic metals --- brucite --- mineral–water interface --- ferrihydrite --- recrystallization --- REEs --- stabilization --- Fe atom exchange --- leaching --- cyanide --- pyrite --- polarization microscopy --- XPS --- surface --- re-adsorption --- gold–(silver) tellurides --- natural porous gold --- interface-coupled dissolution–reprecipitation --- hydrothermal method --- calaverite --- krennerite --- sylvanite --- n/a
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Advanced Glasses, Composites and Ceramics for High-Growth Industries (CoACH) was a European Training Network (ETN) project (http://www.coach-etn.eu/) funded by the Horizon 2020 program. CoACH involved multiple actors in the innovation ecosystem for advanced materials, composed of five universities and ten enterprises in seven different European countries. The project studied the next generation of materials that could bring innovation in the healthcare, construction, and energy sectors, among others, from new bioactive glasses for bone implants to eco-friendly cements and new environmentally friendly thermoelectrics for energy conversion. The novel materials developed in the CoACH project pave the way for innovative products, improved cost competitiveness, and positive environmental impact. The present Special Issue contains 14 papers resulting from the CoACH project, showcasing the breadth of materials and processes developed during the project.
graphitization --- wood-derived biocarbon --- thermal conductivity --- Thermoelectrics --- GeTe --- Al-doping --- Ba-doping --- loss of band convergence --- lowered zT --- geopolymer composite --- wastes incorporation --- cellulose fibers --- cellulose modification --- solid-liquid interdiffusion (SLID) bonding --- transient-liquid phase bonding (TLPB) --- skutterudite --- high-temperature thermoelectric material --- joining --- glass recycling --- alkali activation --- gel casting --- glass foams --- phosphate glass --- oxyfluoride phosphate glass --- Er2O3-doped particles --- direct particle doping --- Er3+ luminescence property --- glass–ceramic --- shear strength --- elastic modulus --- SOFC --- SOEC --- SOC --- mechanical strength --- flexural biaxial test --- ball-on-3-balls test --- fractography --- residual stresses --- evanescent wave optical fiber sensors --- diffusion --- glass fiber-reinforced polymers --- testing and aging --- Zinc --- silver-doped mesoporous glass --- chitosan --- PCL --- Vicryl Plus suture --- dip coating --- polydopamine --- silver --- antibacterial --- biocompatibility --- bioactive glass-ceramic --- coatings --- Thermoelectrics --- oxidation resistance --- hybrid-coating --- alkali activation --- inorganic gel casting --- glass–ceramic foams --- waste glass --- fly ash --- PMCs --- GFRPs --- seawater exposure --- diffusion --- ageing --- accelerated testing --- gravimetric --- DMA
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Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
fisheries management --- muscle texture --- Scyliorhinus canicula --- sharks --- stress --- African catfish (Clarias gariepinus) --- growth --- feed efficiency --- elevated phosphate concentrations --- welfare --- Danio rerio --- fractal analysis --- nociception --- pain --- stereotypical behaviour --- Danio rerio --- structural complexity --- aggression --- territorial --- boldness --- fertilisation success --- aggressive interaction --- social stress --- fighting ability --- social rank --- social communication --- aquaculture --- Amyloodinium ocellatum --- age --- physiological response --- hematology --- histopathology --- welfare --- fish welfare --- ethology --- FishEthoBase --- risk analysis --- welfare scores --- welfare criteria --- framework --- animal behavior --- fish welfare --- positive welfare --- welfare enhancement --- negative and positive affect --- motivation --- n/a
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The peroxiredoxin family was discovered approximately 30 years ago and is now recognized as one of the most important families of enzymes related to antioxidant defense and cellular signaling. Peroxiredoxin 6 shares the basic enzymatic functions that characterize this family, but also exhibits several unique and crucial activities. These include the ability to reduce phospholipid hydroperoxides, phospholipase A2 activity, and an acyl transferase activity that is important in phospholipid remodeling. This book describes the available models for investigating the unique functions of PRDX6 and its role in normal physiological function, as well its roles in the pathophysiology of diseases including cancer, diseases of the eye, and male fertility.
glutathione peroxidase --- phospholipase A2 --- inflammation --- lipid peroxidation --- NADPH (nicotinamide adenine dinucleotide phosphate) oxidase --- phospholipid hydroperoxide --- spermatozoa --- oxidative stress --- reactive oxygen species --- fertilization --- sperm capacitation --- Prdx6 --- cornea --- Fuchs’ endothelial corneal dystrophy --- lipid peroxidation --- mitochondrial membrane potential --- peroxiredoxin 6 --- surfactant protein A --- phospholipase A2 --- drug delivery --- liposomes --- substrate binding --- sulfinic acid --- Prdx6 structure --- mass spectroscopic analysis --- peroxiredoxin 6 --- ionizing radiation --- radioprotection --- antioxidant activity --- peroxidatic cysteine --- thioredoxin fold --- sulfonic/sulfinic acid --- phospholipase A2 activity --- reactive oxygen species --- Peroxiredoxin --- Prdx6 --- PLA2 activity --- 1-Cys Prdx --- phospholipase A2 --- glutathione peroxidase --- reactive oxygen species --- redox balance --- endothelium --- inflammation --- diabetes --- peroxidase --- phospholipase A2 --- lipid peroxidation --- phospholipid hydroperoxide --- knockout mouse --- knock-in mouse --- membrane repair --- n/a
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Kinetics and reactor modeling for heterogeneous catalytic reactions are prominent tools for investigating and understanding catalyst functionalities at nanoscale and the related rates of complex reaction networks. This book illustrates some examples related to the transformation of simple to more complex feedstocks, including different types of reactor designs, i.e., steady-state, transient plug flow reactors, and TAP reactors for which there is sometimes a strong gap in the operating conditions from ultra-high-vacuum to high-pressure conditions. In conjunction, new methodologies have emerged, giving rise to more robust microkinetics models. As exemplified, they include the kinetics and the dynamics of the reactors and span a large range of length and time scales. The objective of this Special Issue is to provide contributions that can illustrate recent advances and novel methodologies for elucidating the kinetics of heterogeneous reactions and the necessary multiscale approach for optimizing the reactor design. This book is dedicated to postgraduate and scientific researchers, and experts in heterogeneous catalysis. It may also serve as a source of original information for the elaboration of lessons on catalysis for Master students.
2,3-Butanediol dehydration --- 1,3-Butadiene --- Methyl Ethyl Ketone --- amorphous calcium phosphate --- reactor modeling --- pilot-scale fixed-bed reactor --- gas-phase oxidation --- HNO3 --- hierarchical graphite felts --- selective oxidation --- H2S --- heats of adsorption --- FTIR spectroscopy --- AEIR method --- Temkin model --- kinetics --- kinetic model --- microkinetics --- cracking --- methanol-to-olefins (MTO) --- zeolite --- ZSM-5 --- ZSM-23 --- SAPO-18 --- SAPO-34 --- transient kinetics --- TAP reactor --- temporal analysis of products --- ammonia decomposition --- internal effectiveness factor --- effective diffusion coefficient --- N2O --- catalytic decomposition --- cobalt mixed oxide --- alkali metal --- promoter --- power-law --- Langmuir–Hinshelwood --- kinetic modeling --- Pd/?-Al2O3 --- catalytic combustion --- automation --- digitalization --- mechanism analysis --- rhodium --- methane --- n/a
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Photoactivity represents the ability of a material, generally speaking a semiconductor, to become active when interacting with light. It can be declined in many ways, and several functionalities arising from this behavior of materials can be exploited, all leading to positive repercussions on our environment. There are several classes of effects of photoactivity, all of which have been deeply investigated in the last few decades, allowing to develop more and more efficient materials and devices. All of them share a common point, that is, the interaction of a material with light, although many different materials are taken into account depending on the effect desired—from elemental semiconductors like silicon, to more complex compounds like CdTe or GaAs, to metal oxides like TiO2 and ZnO. Given the broadness of the field, a huge number of works fall within this topic, and new areas of discovery are constantly explored. The special issue “Novel Photoactive Materials” has been proposed as a means to present recent developments in the field, and for this reason the articles included touch different aspects of photoactivity, from photocatalysis to photovoltaics to light emitting materials.
organometal --- crystallinity --- surfactant --- confocal microscope --- nanostructured materials --- titanium dioxide --- anodizing --- photocatalysis --- toluene --- rhodamine B --- hydrothermal synthesis --- silver phosphate --- degradation --- low power white-light LED irradiation --- broadband spectra --- photocatalysis --- Fe/N-TiO2 --- sol-gel --- hydrothermal --- photocatalytic --- visible-light --- electron transport material --- titanium oxide --- charge dynamics --- metal-halides perovskites --- advanced oxidation processes --- bio-based substances --- hybrid nanomaterials --- magnetic materials --- photo Fenton --- caffeine --- perovskite solar cell --- DFT calculations --- mechanical property --- CH3 --- titanium(IV) oxo-clusters --- photoactivity --- band gap modification --- photoluminescence --- DFT calculations --- composite materials --- ZnO --- photo-oxidation --- 4-chlorophenol --- CuxO-ZnO catalyst --- photodeposition --- TiO2 nanoparticles --- alkylalkoxysilane --- stone protection --- water-repellency --- photocatalysis --- UV ageing --- artificial rain --- photo-oxidative degradation --- durability --- photocatalysis --- photovoltaics --- organic light emitting diodes (OLEDs) --- TiO2 --- ZnO --- density functional theory (DFT)
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This Special Issue of Minerals presents recent, select studies that highlight advances in the fields of hydro- and biohydrometallurgy. It aims to attract the interest of readers and especially of young scientists and students in this fascinating scientific discipline.
nitrate --- chalcopyrite --- chloride --- leaching --- seawater --- leaching --- primary sulfide copper --- chalcopyrite --- chloride --- limonitic laterites --- column leaching --- sulphuric acid --- sodium sulfite --- manganese nodules --- leaching --- secondary mining --- slag --- low-grade saprolitic laterite --- counter-current leaching --- pregnant leach solution --- purification --- iron reduction --- reductive mineral dissolution --- Acidithiobacillus --- laterites --- phosphate mineral --- REE --- galvanic effect --- pyrite–arsenopyrite galvanic pair --- electrochemical --- frontier orbital methods --- agglomeration --- curing --- copper sulfide --- chalcopyrite --- pretreatment --- nitrate --- chloride --- iodide-oxidizing bacteria --- bioleaching --- gold --- iodide --- iodine --- triiodide --- gold diiodide --- secondary products --- reducing agent --- waste reuse --- acid media --- municipal solid waste incineration --- bottom ash --- heap leaching --- bioleaching --- metal extraction --- acid leaching --- white metal --- ferric ion --- chloride ion --- bioleaching --- phosphorus --- fluorapatite --- uranium --- leaching --- manganese nodules --- optimization of parameters --- tailings --- laterite --- nickel --- leaching --- jarosite --- precipitation --- n/a
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