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"This new book analyses the strategies, usages and wider implications of crowdsourcing and crowdfunding platforms in the culture and communication industries that are reshaping economic, organizational and social logics. Platforms are the object of considerable hype with a growing global presence. Relying on individual contributions coordinated by social media to finance cultural production (and carry out promotional tasks) is a significant shift, especially when supported by morphing public policies, supposedly enhancing cultural diversity and accessibility. The aim of this book is to propose a critical analysis of these phenomena by questioning what follows from decisions to outsource modes of creation and funding to consumers. Drawing on research carried out within the ‘Collab’ programme backed by the French National Research Agency, the book considers how platforms are used to organize cultural labour and/or to control usages, following a logic of suggestion rather than overt injunction. Four key areas are considered: the history of crowdfunding as a system; whose interests crowdfunding may serve; the implications for digital labour and lastly crowdfunding’s interface with globalization and contemporary capitalism. The book concludes with an assessment of claims that crowdfunding can democratize culture."

crowdsourcing --- culture --- crowdfunding --- participation --- platforms --- arts

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This book consolidates experiences from across Europe on the design, development, implementation and evolution of inter-organisational information infrastructures for healthcare. It provides insights with practical relevance for those involved or interested in the planning and implementation of such infrastructures and includes 11 empirical cases on the introduction of core infrastructural arrangements in different national settings: six cases investigate the use of e-prescriptions and five the public platforms for patient-oriented eHealth services. Both are linked to different types of aims.E-prescription initiatives are usually seen as opportunities to improve healthcare delivery by systematic change (controlling medication costs, improving patient safety and providing rich information for policy making and performance management). Public platforms for patient-oriented eHealth services are seen as opportunities for change and innovation, aiming to strengthen the patients’ role and facilitate a shift from provider-centered healthcare towards patient-centeredness. For both types of initiatives, there is a requirement to mix novelty with pre-existing infrastructural components. The cases are analysed by leading experts in health information systems through a common theoretical framework, exploring the role of the pre-existing sociotechnical basis, i.e. the installed base, and how it fundamentally impacts the evolution of information infrastructures. The book advances an “installed base sensitivity” in decision-making both at the policy/strategy level and at the concrete eHealth design level and shows how practitioners and policy-makers can address the complexity of infrastructures that facilitate information flows across organisational boundaries.

e-prescription --- information systems design --- infrastructure --- public --- patient- oriented web platforms

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Remixers recombine copyright-protected audiovisual material and distribute it via hosting platforms. To what extent does copyright law allow remixing and what is the impact of platforms' policies and filtering mechanisms for user uploads? Henrike Maier employs a comparative legal approach and focuses on the role of creative users' fundamental rights to investigate these questions.

Law --- Copyright --- Audiovisual material --- Hosting Platforms --- Copyright law --- Remixing --- Filtering mechanisms --- Uploadfilter --- Content Filters --- Fair Use --- User generated content --- Mashup --- Comparative Law

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Fernsehen --- TV --- Mediendiskurs --- Grimme-Preis --- Qualität --- Bewertung --- Film --- Grimme Online Award --- Netz --- Internet --- Radio --- Deutscher Radiopreis --- Digitalisierung --- Auszeichnung --- Plattformen --- Unterhaltung --- Medien --- Medientheorie --- Computerspiele --- Mediensoziologie --- Medienwissenschaft --- Television --- Tv --- Media Discourse --- Grimme-preis --- Quality --- Rating --- Web --- Broadcast --- German Radio Award --- Digitalization --- Award --- Platforms --- Entertainment --- Media --- Media Theory --- Computer Games --- Sociology of Media --- Media Studies

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Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging zoonotic coronavirus. First identified in 2012, MERS-CoV has caused over 2460 infections and a fatality rate of about 35% in humans. Similar to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV likely originated from bats; however, different from SARS-CoV, which potentially utilized palm civets as its intermediate hosts, MERS-CoV likely transmits to humans through dromedary camels. Animal models, such as humanized mice and nonhuman primates, have been developed for studying MERS-CoV infection. Currently, there are no vaccines and therapeutics approved for the prevention and treatment of MERS-CoV infection, although a number of them have been developed preclinically or tested clinically. This book covers one editorial and 16 articles (including seven review articles and nine original research papers) written by researchers working in the field of MERS-CoV. It describes the following three main aspects: (1) MERS-CoV epidemiology, transmission, and pathogenesis; (2) current progress on MERS-CoV animal models, vaccines, and therapeutics; and (3) challenges and future prospects for MERS-CoV research. Overall, this book will help researchers in the MERS-CoV field to further advance their work on the virus. It also has important implications for other coronaviruses as well as viruses outside the coronavirus family with pandemic potentials.

mouse model --- hDPP4 --- MERS-CoV --- pseudotyped virus --- authentic virus --- Middle East Respiratory Syndrome Virus --- MERS-CoV --- neutralizing monoclonal antibodies --- MERS-CoV --- MERS-CoV nucleocapsid protein --- murine CD8+ T cell epitope --- MVA vaccine --- MERS-CoV --- mechanism of action --- small-molecule inhibitor --- Drivers --- MERS-CoV --- Qatar --- MERS-CoV --- RBD --- mutation --- peptide --- neutralizing antibody --- combination --- MERS-CoV --- inflammation --- pyroptosis --- complement --- MERS-CoV --- fusion inhibitor --- peptide --- cell–cell fusion --- HKU4 --- coronaviruses --- SARS-CoV --- MERS-CoV --- spike proteins --- animal model --- prevention and treatment --- Coronavirus --- MERS-CoV --- spike protein --- receptor-binding domain --- vaccines --- therapeutics --- lipidomics --- UHPLC–MS --- HCoV-229E --- MERS-CoV --- Middle East respiratory syndrome coronavirus --- severe acute respiratory syndrome coronavirus --- coronavirus spike glycoprotein --- vaccine platforms --- correlates of immunity --- animal models --- Coronavirus --- MERS-CoV --- receptor-binding domain --- therapeutic antibodies --- nanobodies --- cross-neutralization --- MERS-CoV --- camels --- vaccines --- One Health --- MERS-CoV --- transmission --- pathogenesis --- host factors --- DPP4 --- MERS-coronavirus --- transmission --- rabbits --- n/a