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Discussions of Unusual Topics in Fibromyalgia

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ISBN: 9789535138990 9789535139003 9789535140146 Year: Pages: 108 DOI: 10.5772/66578 Language: English
Publisher: IntechOpen
Subject: Internal medicine --- Allergy and Immunology --- Microbiology
Added to DOAB on : 2019-10-03 07:51:51

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This book is a compilation of chapters, of which two chapters review the treatment strategies for fibromyalgia syndrome (FMS), and one chapter describes the role of mitochondrial dysfunction and related pathology in the FMS pathogenesis and reviews the appropriate treatment moieties. This book chapter reviews the phenotypic changes that alter the diagnostic criteria and disease activity measures when FMS is comorbid in three potentially painful selected rheumatic diseases. The introductory preface takes the form of an editorial in which I challenge the concept that inflammation, measured as cytokine activity, plays a prominent role in the FMS pathogenesis. All of these chapters and the Preface are authoritative and accomplished discussions that provide novel perspectives on rarely addressed FMS topics.

Newest Updates in Rheumatology

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Book Series: Rheumatology ISSN: 26319233 ISBN: 9781789843798 9781789843804 Year: Volume: 1 Pages: 130 DOI: 10.5772/intechopen.72557 Language: English
Publisher: IntechOpen
Subject: Internal medicine --- Allergy and Immunology --- Microbiology
Added to DOAB on : 2019-10-03 07:51:52

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This book is a comprehensive guide to rheumatology and includes all possible topics. The book is ideal for all those interested in the field of rheumatology, including students, scientists, and postdocs.

Acute Phase Proteins - Regulation and Functions of Acute Phase Proteins

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ISBN: 9789533072524 Year: Pages: 382 DOI: 10.5772/756 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:48

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The two volumes of Acute Phase Proteins book consist of chapters that give a large panel of fundamental and applied knowledge on one of the major elements of the inflammatory process during the acute phase response, i.e., the acute phase proteins expression and functions that regulate homeostasis. We have organized this book in two volumes - the first volume, mainly containing chapters on structure, biology and functions of APP, the second volume discussing different uses of APP as diagnostic tools in human and veterinary medicine.

Acute Phase Proteins as Early Non-Specific Biomarkers of Human and Veterinary Diseases

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ISBN: 9789533078731 Year: Pages: 422 DOI: 10.5772/1045 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:48

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The two volumes of Acute Phase Proteins book consist of chapters that give a large panel of fundamental and applied knowledge on one of the major elements of the inflammatory process during the acute phase response, i.e., the acute phase proteins expression and functions that regulate homeostasis. We have organized this book in two volumes - the first volume, mainly containing chapters on structure, biology and functions of APP, the second volume discussing different uses of APP as diagnostic tools in human and veterinary medicine.

New Developments in the Pathogenesis of Rheumatoid Arthritis

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ISBN: 9789535129691 9789535129707 Year: Pages: 164 DOI: 10.5772/63175 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:49

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The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-6, and also T cells and B cells, reinforced the pathogenetic role of the respective factors. ACPAs, induced by cigarette smoking and periodontitis in individuals with HLA-DRB1 shared epitope, appear to be autoantigens that initiate the inflammatory immune response in RA. MicroRNAs, part of epigenetic mechanisms, which also include DNA methylation, and histone modification, as well as microbiota, the composition of microbes in body cavities, also appear to influence arthritis and are discussed in this book.

Lupus

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ISBN: 9789535131793 9789535131809 Year: Pages: 230 DOI: 10.5772/65819 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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Lupus is a new book that will serve as perfect update to lupus for all those who are studying/working at different levels starting from graduate students up to senior investigators. This book provides a comprehensive guide to the latest issues and new developments in the field of lupus. The contents are based on different authors extensive research experience in lupus whether for basic or clinical specialties. Divided into four sections, each one covers the basic concept that will be equally valuable both for the expert and for those who are beginners in this field.

A Comprehensive Review of Urticaria and Angioedema

Authors: ---
ISBN: 9789535131670 9789535131687 Year: Pages: 250 DOI: 10.5772/65526 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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This book contains the latest advances and scientific knowledge from the leading experts in urticaria and angioedema. The book consists of 15 chapters in which urticaria classification, urticaria etiopathogenesis, urticaria clinics, urticarial syndromes, angioedemas, diagnosis, pathogenesis and pathophysiology of urticaria, and treatment options are discussed. This book also emphasizes on the various laboratory tests necessary for urticarias. One chapter of the book is devoted to comorbidities in chronic spontaneous urticaria. Another chapter is related with pathophysiology and treatment of hereditary angioedema. We are grateful to all the contributors and leading experts for their valuable chapters, which provide an in-depth view of all aspects of the content, backed with the most current literature in the field. We hope that this book will provide interesting knowledge and serve as a comprehensive guide to many physicians dealing with urticaria and angioedemas in their clinical practice.

Behcet's Disease

Authors: ---
ISBN: 9789535132257 9789535132264 Year: Pages: 220 DOI: 10.5772/65884 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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Behcet's disease is a multisystem inflammatory disease with unknown etiology and has a unique geographic distribution. It is characterized by recurrent oral aphthous lesions, recurrent uveitis, skin lesions, and genital ulcerations. However, it may involve the eye, joints, and cardiovascular, gastrointestinal, and neurological systems at varying degrees as well as the skin and mucous membranes. The disease may manifest itself in a wide spectrum of symptoms ranging from mild symptoms to life-threatening symptoms or severe symptoms that may create permanent sequelae. Knowing the nature of the disease will make it easier to diagnose and manage the disease. This book was written by expert authors, and detailed epidemiology, etiopathogenesis, mucocutaneous findings, and systemic involvement of Behcet's disease are presented to readers.

Nonsteroidal Anti-Inflammatory Drugs

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ISBN: 9789535134435 9789535134442 Year: Pages: 162 DOI: 10.5772/65816 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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This book intends to provide the reader with a comprehensive overview about the state of the art regarding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in physical and rehabilitation medicine and the study of the pharmacodynamics of existing and newly introduced NSAIDs in the management of pain and inflammation. It will also elaborate and refine already known knowledge on the mechanism(s) of nonsteroidal anti-inflammatory agents. This book may provide additional knowledge about the design and development of new drug delivery systems loaded with NSAIDs potentially useful in the treatment of chronic inflammatory-based diseases following circadian cycle, uses of NSAIDs as a source of medicinal plants, and the adverse effects and drug interactions of the nonsteroidal anti-inflammatory drugs.

Systemic Sclerosis

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ISBN: 9789535135470 9789535135487 Year: Pages: 216 DOI: 10.5772/63286 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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Systemic sclerosis is a rare autoimmune disease characterized by immunological alterations, small vessel vasculopathy, and skin and other organ fibrosis. Despite progress in the knowledge of pathogenic steps and therapeutic options, when compared with other rheumatic conditions, it shows the lowest life expectancy rate. Early diagnosis is important as early treatment could lead to better outcomes. Great progress has been made in the treatment of specific symptoms; however, there are still no disease-modifying drugs that are able to control the overall disease activity satisfactorily. This book covers the latest knowledge in systemic sclerosis from pathophysiology to clinical presentation and management. Hopefully, this book will be a useful resource to students, residents, rheumatologists, dermatologist, and anyone interested in this fascinating disease.

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