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Introduction to Swiss Law

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Book Series: sui generis ISBN: 9783941159242 9783941159242 Year: Pages: 452 DOI: 10.24921/2018.94115924 Language: English
Publisher: Carl Grossmann Verlag
Subject: Law
Added to DOAB on : 2018-09-11 11:01:04
License: Carl Grossmann Verlag

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What are the origins of direct democracy in Switzerland? How does the Swiss judiciary function? What are the principles of Swiss civil, contract and administrative law? What is the role of public service broadcasting in the political decision making process? What are the leading cases in tax law? What forms of euthanasia are legal in Switzerland? In this introduction 13 legal scholars of the University of Zürich Law Faculty try to answer these questions and give the reader an overview of Swiss public, private and criminal law. As the first comprehensive introduction to Swiss law in English, it is addressed to both lawyers from abroad and incoming students.&#xD;

System transferability of public hospital facility management between Germany and Iran

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Book Series: Karlsruher Reihe Bauwirtschaft, Immobilien und Facility Management / Institut für Technologie und Management im Baubetrieb, Universität Karlsruhe (TH) ISSN: 18675867 ISBN: 9783866443952 Year: Volume: 4 Pages: XV, 385 p. DOI: 10.5445/KSP/1000012005 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: General and Civil Engineering
Added to DOAB on : 2019-07-30 20:02:01
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The subject of this PhD-thesis is the transferability of Facility Management (FM) by using the example of hospitals in Germany and Iran. The intention is to determine the status and significance of facility management in the project countries, to analyse similarities, semblances and differences in order to develop a system transferability model.

The role of the immune system in the pathogenesis of diabetic complications

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193523 Year: Pages: 95 DOI: 10.3389/978-2-88919-352-3 Language: English
Publisher: Frontiers Media SA
Subject: Nutrition and Food Sciences --- Neurology --- Science (General) --- Public Health --- Internal medicine --- Medicine (General)
Added to DOAB on : 2016-03-10 08:14:32
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The main causes of morbidity and mortality in diabetes are macrovasular and microvascular complications, including atherosclerosis, nephropathy, and retinopathy. As the definition of atherosclerosis as a chronic, smoldering, inflammatory disease has gained general acceptance, the attention of researchers has focused on the triggers of chronic vascular inflammation. The oxidation and other forms of modification of lipids and lipoproteins have emerged as a major pathogenic factor in atherosclerosis, with a significant interaction with the immune system. Modified lipoproteins by themselves are proinflammatory through the activation of the innate immune system as a consequence of the interaction with scavenger receptors and/or toll-like receptors expressed by a variety of cell types, including phagocytic cells and dendritic cells. A variety of modified forms of LDL (mLDL), including oxidized, malondialdehyde-modified, and Advanced Glycation End-product-modified LDL induce autoimmune responses in humans. Those modifications seem enhanced in diabetes, and the progression of atherosclerosis is accelerated in diabetic patients. The immune response to all forms of mLDL results in both activation of T cells in the arterial wall and in an autoimmune response characterized by the formation of IgG antibodies. Both arms of the immune response are believed to play a role in vascular inflammation. While the cell response is likely to activate resident macrophages, the humoral immune response results in the production of IgG antibodies that bind to specific epitopes in modified forms of LDL, generate immune complexes both intra- and extravascularly, and those complexes are able to activate the classical pathway of the complement system as well as phagocytic cells via Fc? receptors. In vitro studies suggest that the pro-inflammatory activity of immune complexes containing mLDL is several-fold higher than that of the modified LDL molecules by themselves. Clinical studies have provided significant support to the pathogenic role of immune complexes containing modified LDL in the development of atherosclerotic complications in patients with both type 1 and type 2 diabetes. At the same time, there is increasing evidence that the formation of immune complexes containing modified forms of LDL may also be involved in the pathogenesis of diabetic nephropathy and retinopathy. These are areas in which more research is needed to fully understand the pathogenic mechanisms activated by those immune complexes. Of interest is the fact that animal models have suggested the possibility of modifying the adaptive humoral immune response in ways that would result in slowing down, and perhaps prevent, the atherosclerotic process. This possibility is sufficiently alluring as to justify increased research efforts, both in animal models (including diabetic animals) and translational clinical studies. The manipulation of the T regulatory population is another area of potential translational impact, which has hardly been explored. Indeed at this point of time, what seems to be a high priority is an increased and open interchange of information among investigators, trying to reach a better general understanding and integration of knowledge generated from a variety of approaches and perspectives. This Research Topic provided an optimal platform for this open interchange of information. We encouraged interested scientists to submit mini-reviews, methods papers, review articles, perspectives and original research articles covering this topic in all its diversity to facilitate the communication of perspectives and new information between scientists interested in understanding the multiple implications of the involvement of the immune system in the pathogenesis of diabetic complications.

Alternanz - die EU-Konzeption für die Berufsausbildung. Erfahrungslernen Hand in Hand mit Abschnitten systematischer Ausbildung dargestellt unter Einbeziehung von Ergebnissen aus Ländervergleichen

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Book Series: Reihe Materialien zur Berufs- und Arbeitspaedagogik ISBN: 3937300155 Year: Volume: 12 Pages: XVI, 202 p. DOI: 10.5445/KSP/1452004 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Sociology
Added to DOAB on : 2019-07-30 20:01:57

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Der Rat der EU hatte im Jahre 1979 nach breitem Konsens Leitlinien zur alternierenden Ausbildung verabschiedet. Danach ist der regelmäßige Wechsel zwischen Erfahrungslernen in der Ernstsituation des Betriebs und Abschnitten systematischer Ausbildung in Ausbildungszentren oder Schulen Grundprinzip beruflicher Qualifizierung auf allen Ebenen. Allgemeine und berufliche Bildung - im betriebsgebundenem System und berufsqualifizierenden Vollzeitschulen - sind in ein Gesamtsystem zu integrieren, das die fortlaufende Anpassung an die technologische und wirtschaftliche Entwicklung ermöglicht.Deutschland hat bisher diesen Modernisierungsprozess noch nicht eingeleitet. Der vorliegende Band zeigt Wege auf, die das deutsche Berufsbildungssystem aus seinem Rückstand herausführen können.

Interactions between the mammalian main and accessory olfactory systems

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889192564 Year: Pages: 155 DOI: 10.3389/978-2-88919-256-4 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2015-11-16 15:44:59
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The functional cross-talk and structural interaction between the main and accessory olfactory bulb is a central problem in mammalian sensory neurobiology. The early supposition that volatile substances and pheromones, most of them hydrosoluble molecules, are exclusively sensed and decoded by the main (MOS) and accessory olfactory systems (AOS), respectively, needs to be revised. In fact, a large number of structural and functional evidences accumulated during the last few decades, suggests that rather than separated entities, the MOS and AOS act synergically, bringing about physiological and behavioural responses. The goal of the present Research Topic will be to gather original research studies and revision papers, performed by the most authoritative research groups that have recently contributed to the broad area of sensory neurobiology. Special attention should be given to contributions addressed to the MOB and AOB cross-talk, involving current neuroanatomical techniques.

Software-Infrastruktur. Von analytischer Perspektive zu konstruktiver Orientierung

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ISBN: 9783980898553 Year: Pages: 320 DOI: 10.15460/HUP.7 Language: German
Publisher: Hamburg University Press
Subject: Computer Science
Added to DOAB on : 2019-01-15 13:33:24

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The term "infrastructure" is used here for information systems. Software applications are related to other software and consist of software of different origins. In their networking, software is under the limited influence of different actors. Nowadays, software development is mainly concerned with further development, parameterization and configuration. Software infrastructure development must therefore deal with existing software and be carried out in complex contexts, taking into account a sharply increased number of interests and opportunities for interaction. Interference is recognized as a particular problem in infrastructure development. The proposed interference management addresses this. The core point of the extended evolutionary software development process is the continuous development of the relevant components and actors of the infrastructure against the background of our own development project, taking into account the various interests.

Il Governo del Sistema Integrato Città-Trasporti-Energia

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Book Series: Smart City, Urban Planning for a Sustainable Future ISSN: 2611-6103 ISBN: 9788868870133 Year: Volume: 3 Pages: 151 DOI: 10.6093/978-88-6887-013-3 Language: Italian
Publisher: FedOA - Federico II University Press
Subject: Architecture
Added to DOAB on : 2018-06-12 15:48:09
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heories about the origins and developments of modern cities seem to agree, without exception, to a point: the city is the place of maximum concentration of exchange. Activities, in fact, are located into urban and metropolitan agglomerations to minimize the resources needed to meet the growing need for relationships and exchanges with other activities. In recent years, the concentration and specialization of these activities have led to an extraordinary increase in intensity and quality of exchange needs, with the obvious consequence of congestion in most metropolitan areas with predictable consequences on the sustainability of urban areas, on the quality of life of its inhabitants and on the energy consumption associated with the growing demand for mobility. As a result, in recent years, several authors have argued for greater integration between urban planning policies, mobility management and energy efficiency. In this context, this volume aims to provide a contribution in this direction and presents the results of a research project aimed at the development of an integrated city-mobility-energy governance model.In particular, the first part of this work give an overview of the complex relationships between mobility, energy consumption and built environment through a meta-analysis of the recent literature. Specifically, in this section, the two main sources of energy consumption in urban areas (energy consumption in the residential sector and energy consumption of transport) are considered. These sectors represent, according to the latest estimates, respectively 32% and 35% of the final energy consumption. The section introduces several characteristics of the built environment such as density, functional mix or accessibility and described as such factors affect energy consumption in the transport and residential sectors. Understanding these relationships is of crucial importance for the development of a coordinated mix of actions aimed at reducing energy consumption in urban areas. Subsequently, the main models present in the literature for estimating residential energy consumption and urban transport energy consumption are presented, paying particular attention to the strengths and weaknesses of each model, the complexity and the related technical and operational aspects related to the implementation of such models.In the second part of this work, the focus is on the techniques for the representation and classification of energy consumption in urban areas through an application to the case study of Naples. Particularly, this section places particular emphasis on the new opportunities offered by the Geographic Information Systems (GIS) and by the increasing availability of new data sources. The work integrates the use of "traditional" data sources such as census surveys, new data sources (in particular open and large data) with spatial analyzes developed ad hoc to provide exhaustive knowledge of energy consumption patterns within the city of Naples. The proposed methodology is validated by comparing the results obtained with the previously available data for the study area and by the implementation of spatial statistical analyzes in a GIS environment. The proposed methodology is a useful tool for public decision-makers and policy makers aimed at defining integrated government strategies for the reducing and optimizing of public and private energy consumption. In particular, the methodology described in this work is useful for classifying and representing energy consumption on an urban scale, for the identification of critical areas in terms of consumption, and for ex post evaluation of interventions on the urban system.

Optimierung der Betriebsführung mobiler Arbeitsmaschinen : Ansatz für ein Gesamtmaschinenmanagement mobiler Arbeitsmaschinen

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Book Series: Karlsruher Schriftenreihe Fahrzeugsystemtechnik / Institut für Fahrzeugsystemtechnik ISSN: 18696058 ISBN: 9783866445369 Year: Volume: 3 Pages: XII, 125 p. DOI: 10.5445/KSP/1000019044 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:58
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Zunächst wird ein praxisorientiertes Dieselmotormodell für den Einsatz in der Systemsimulation entwickelt. Es bildet die Interaktion zwischen Motorsteuergerät und Triebwerk sowie ihre Auswirkungen auf das transiente Drehzahl- und Verbrauchsverhalten ab.Anschließend wird für die Gesamtmaschine ein Optimierungsansatz entwickelt, dessen Kern in der Berücksichtigung des dynamischen Komponentenverhaltens zur Identifikation der wirkungsgradoptimalen Betriebsführung für einen Lastzyklus liegt.

Investigating the human brainstem with structural and functional MRI

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889192472 Year: Pages: 92 DOI: 10.3389/978-2-88919-247-2 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2015-11-16 15:44:59
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The brainstem is one of the least understood parts of the human brain despite its prime importance for the maintenance of basic vital functions. Owing to its role as a relay station between spinal cord, cerebellum and neocortex, the brainstem contains vital nodes of all functional systems in the central nervous system, including the visual, auditory, gustatory, vestibular, somatic and visceral senses, and the somatomotor as well as autonomic nervous systems. While the brainstem has been extensively studied in animals using invasive methods, human studies remain scarce. Magnetic resonance imaging (MRI) as a non-invasive and widely available method is one possibility to access the brainstem in humans and measure its structure as well as function. The close vicinity of the brainstem to large arteries and ventricles and the small size of the anatomical structures, however, place high demands on imaging as well as data analysis methods. Nevertheless, the field of brainstem-(f)MRI has significantly advanced in the past few years, largely due to the development of several new tools that facilitate studying this critical part of the human brain. Within this scope, the goal of this Research Topic is to compile work representing the state of the art in functional and structural MRI of the human brainstem.

Nachhaltigkeitsindikatoren und Partizipation

Authors: --- --- --- --- et al.
ISBN: 9783980822305 Year: Pages: 142 DOI: 10.15460/HUP.45 Language: German
Publisher: Hamburg University Press
Subject: Economics
Added to DOAB on : 2019-01-15 13:33:23

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The workshop documentation was developed as part of the inter-university project "Participatory development of indicators of sustainability. A contribution to a process-oriented sustainability strategy ". It was carried out at the beginning of March 2000 to April 2001 by scientists from the University of Hamburg, the Hamburg University of Economics and Politics (Hochschule für Wirtschaft und Politik, HWP), the University of the Federal Armed Forces Hamburg (Universität der Bundeswehr) and the Wuppertal Institute for Climate, Environment and Energy (Wuppertal Institut für Klima, Umwelt, Energie). The workshop documented here took place on March 23, 2001 at the University of the German Armed Forces. The project team presented its work results to an audience from science and practice for discussion. Participants included representatives from companies, government departments at state and municipal level, educational institutions, consulting companies, statistical offices and associations, universities and research institutions from social, engineering and natural sciences disciplines. They came from Hamburg, Schleswig-Holstein, Lower Saxony and Baden-Württemberg. The documentation contains the lectures of four project participants, in which central results of the project are presented, and corrections by external scientists and experts. A summary of the discussion follows.

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