Search results: Found 2

Listing 1 - 2 of 2
Sort by
Neurophysiology in Alzheimer's Disease and Dementia

Author:
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199303 Year: Pages: 106 DOI: 10.3389/978-2-88919-930-3 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2016-01-19 14:05:46
License:

Loading...
Export citation

Choose an application

Abstract

Alzheimer's disease (AD) and dementia are the most common neurodegenerative disorder. Since the number of individuals with AD and dementia is expected to increase considerably in the near future, reliable treatment and diagnosis are critical. EEG and neurophysiological technique could be used as a cost-effective screening tool for early detection and diagnosis in the Mild Cognitive Impairment (MCI) stage. The aim in neurophysiology research is to develop signal processing methods that improve the specificity for diagnosing dementia; we wish to discover signal features that not only significantly differ in AD patients, but also allow us to reliably separate AD patients and control subjects. This approach is valuable for clinical purposes (as diagnostic tool for dementia), and it also more fundamentally contributes to a better understanding of brain dynamics of MCI patients. Finally, the development of neurophysiological biomarker could be useful in monitoring pharmacological treatments. The main focus of this special issue will be on the most recent developments and ideas in the field of EEG and neurophysiology which will enable us to extract features that improve the specificity for diagnosing AD and dementia.

The CA3 region of the hippocampus: how is it? what is it for? how does it do it?

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889196319 Year: Pages: 165 DOI: 10.3389/978-2-88919-631-9 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2016-08-16 10:34:25
License:

Loading...
Export citation

Choose an application

Abstract

The aim of this special topic is to bring together experts on the cellular and molecular mechanisms regulating the wiring properties of the CA3 hippocampal microcircuit in both physiological and pathological conditions, synaptic plasticity, behavior and cognition.We will particularly emphasize the dual glutamatergic and GABAergic phenotype of MF-CA3 synapses at early developmental stages and the steps that regulate the integration of newly generated neurons into the adult dentate gyrus-CA3 circuit.

Listing 1 - 2 of 2
Sort by
Narrow your search

Publisher

Frontiers Media SA (2)


License

CC by (2)


Language

english (2)


Year
From To Submit

2016 (1)

2015 (1)

-->